This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Alendronic Acid + Vitamin D3 belongs to the family called vitamin D analogue, which is used to treat certain bone conditions, including osteoporosis. 

Mechanism of Action of undefined

Alendronic Acid + Vitamin D3 is used to treat certain bone conditions, including osteoporosis (thinning of the bone), in men and postmenopausal women. Alendronic Acid inhibits bone resorption by targeting osteoclasts, the cells responsible for breaking down bone tissue. It binds to hydroxyapatite crystals in bone, reducing their dissolution and preventing excessive bone loss. Vitamin D3, aids in calcium absorption, which is vital for bone mineralization and strength. Together, they work to maintain bone density and reduce the risk of fractures in osteoporosis patients.

Uses of undefined

Alendronic Acid + Vitamin D3 is used to treat certain bone conditions, including osteoporosis (thinning of the bone),  in men and postmenopausal women. Alendronic Acid inhibits bone resorption by targeting osteoclasts, the cells responsible for breaking down bone tissue. It binds to hydroxyapatite crystals in bone, reducing their dissolution and preventing excessive bone loss. Vitamin D3, aids in calcium absorption, which is vital for bone mineralization and strength. Together, they work to maintain bone density and reduce the risk of fractures in osteoporosis patients.

undefined Drug administaration and Dosage available

To take Alendronic Acid + Vitamin D3, shake the bottle, measure the correct dose with a dropper or measuring spoon, and consume it directly in your mouth or mix it with a small amount of liquid or food. Do not exceed the recommended dose unless advised by a healthcare professional. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Warnings, Precautions and Side Effects of undefined

Warnings

Do not consume Alendronic Acid + Vitamin D3 if you are allergic to Alendronic Acid + Vitamin D3 or any of its ingredients. Avoid consuming this medicine if you have high levels of vitamin D ( (hypervitaminosis D), or calcium (hypercalcemia) or high urine levels of calcium (hypercalciuria) in your blood and if you have kidney stones or have serious kidney problems. Inform your doctor if you are pregnant or planning to get pregnant, or think you are already breastfeeding. During pregnancy and breastfeeding, seeking advice from your doctor before taking this medicine is essential. Extra vitamin D should not be taken without your doctor's supervision, as it can harm your baby. 

Precautions

Before taking the Alendronic Acid + Vitamin D3. Before taking the medicine, inform your doctor if you are pregnant or planning to get pregnant or think you may be already pregnant, or if you are breastfeeding. Before taking Alendronic Acid + Vitamin D3, notify your doctor if you have kidney damage, are receiving treatment for heart disease, have sarcoidosis, or are already taking additional calcium or vitamin D doses. Your doctor will monitor the blood or blood calcium levels during the treatment. This medicine should be used cautiously in kidney patients. Before starting the treatment, inform your doctor about pre-existing kidney conditions. Notifying your doctor if you are pregnant and breastfeeding before taking this medicine. Extra vitamin D should not be taken without your doctor's supervision, as it can harm your baby. 

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Alendronic Acid + Vitamin D3 is generally safe to consume and is not associated with significant side effects. However, consult your dietician for advice if you experience any unfamiliar side effects.

Word Of Advice

Kidney patients should take Alendronic Acid + Vitamin D3 cautiously and inform their doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information. Keep out of sight and reach of pets and children. Do not freeze the medicine. Do not store above 30°C. Always check the expiry date before consuming it.

Frequently Asked Question

References

  1. GCreo Pharma Ltd., Electronic Medicines Compendium (EMC), [Revised on Jun 2017] [Accessed on 15th Sept 2023], https://www.medicines.org.uk/emc/files/pil.8638.pdf
  2. Organon Global Inc., [Revised on Jun 2021] [Accessed on 15th Sept 2023], https://www.organon.com/product/usa/pi_circulars/f/fosamax/fosamax_plus_d_mg.pdf
  3. Jill Jin, Vitamin D and Calcium Supplements for Preventing Fractures, JAMA, 2018, 319(15), 1630, https://jamanetwork.com/journals/jama/fullarticle/2678617
  4. KD Tripathi, Hormones and Drugs Affecting Calcium Balance, Essentials of Medical Pharmacology, 8th Edition, 2019, 360-372.
  5. Daniel D. Bickle, Agents that affect bone mineral homeostasis, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 772-791.

Disclaimer

The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.