This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
The U.S. FDA approved Atracurium Besylate on July 18, 1997. Atracurium Besylate belongs to the medication class known as muscle relaxants. It works by blocking the transmission of nerve signals to the muscles.
Mechanism of Action of undefined
Atracurium Besylate blocks the transmission of nerve signals to the muscles. When a nerve signal reaches a muscle, it releases a neurotransmitter called acetylcholine, which binds to receptors on the muscle cells, leading to muscle contraction. Atracurium works by competitively binding to these acetylcholine receptors, preventing acetylcholine from attaching and causing muscle contraction.
Uses of undefined
Atracurium Besylate is used in various medical settings, including surgeries, other medical procedures, and intensive care units. It is used specifically during general anesthesia to facilitate tracheal intubation (insertion of a tube into the windpipe) and to enable controlled ventilation.
undefined Drug administaration and Dosage available
Atracurium Besylate will be administered to you by a healthcare professional in a hospital setting. It is usually administered in a vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Warnings, Precautions and Side Effects of undefined
Warnings
Atracurium Besylate should not be consumed if you are allergic to Atracurium Besylate or any of its ingredients in the medication. Do not use this medicine if you are allergic to Atracurium Besylate or any of its ingredients. Before starting the treatment, notify your doctor if you have if you have a neuromuscular disease that affects your muscles or their nervous control, such as myasthenia gravis or Eaton-Lambert syndrome. Additionally, inform your doctor if you have a severe electrolyte disorder, widespread cancer (carcinomatosis), or sensitivity to histamine. This medicine is not recommended for neonates (children under one month old). If necessary, the dose should be significantly reduced for newborns or premature babies.
Precautions
Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding. Mention any history of allergy, asthma, or bronchospasm, as well as any burns or issues related to inadequate circulatory filling (hypovolemia). For further questions or concerns, consult your doctor.
Side Effects
The most common side effects of Atracurium Besylate are tachycardia (rapid heartbeat), temporary hypotension (low blood pressure), wheezing, bronchospasm (asthma-like symptoms), skin flushing, and urticaria (nettle rash).
Word Of Advice
Notify your doctor if you experience any serious side effects to avoid the risk of certain conditions. Before starting the treatment, inform your doctor about all the underlying medical conditions. Providing this information helps ensure the safe and effective use of Atracurium during medical procedures. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information. Keep out of sight and reach of pets and children. Do not freeze the medicine. Store below 2°C - 8°C. Always check the expiry date before consuming it.
Frequently Asked Question
References
- Mercury Pharmaceuticals Limited; Electronic medicines compendium (emc); [Revised on April 2020] [ Accessed on 27th July 2023], https://www.medicines.org.uk/emc/files/pil.2797.pdf
- Baxter Healthcare Corporation; US Food and Drug Administration; [Revised on June 2019] [Accessed on 27th July 2023], label (fda.gov)
- Drugs.com; [Revised on March 2023] [ Accessed on 27th July 2023], Atracurium Besylate Injection: Package Insert - Drugs.com
- Satyanarayana U, Chakrapani U, Biochemistry, Mineral metabolism, 4th edition, 2013, 404.
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you are eligible to receive this treatment.
