This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Curcumin, Piperine is approved for medical use to manage cellular damage, inflammation, and oxidative stress during cancer treatment.

Mechanism of Action of undefined

Curcumin + Piperine works synergistically to reduce inflammation and oxidative stress in the body by regulating various signaling pathways and gene expressions related to inflammation, also by inhibiting pro-inflammatory enzymes, and enhancing the absorption of other compounds.

Uses of undefined

Curcumin and piperine are the allies during cancer treatments (chemotherapy or radiation therapy) and help lower bad cholesterol. They aid in reducing inflammation and prevent cellular damage and oxidative stress during cancer.

undefined Drug administaration and Dosage available

Curcumin and piperine combination is administered as oral supplements under the physician's direction. Your doctor will decide the dose and duration of Curcumin and piperine based on the disease condition and other factors.

Warnings, Precautions and Side Effects of undefined

Warnings

Some people may be allergic to this tablet and experience hives, itching, or difficulty breathing. If you experience these symptoms after taking this drug, you should stop immediately and seek a medical emergency. This drug can stimulate the production of bile, which could be problematic for people with gallbladder disease or gallstones. If you previously had a history of gallbladder-related disease, speak immediately with your doctor before taking this tablet or any other supplements. In addition, if you are scheduled to undergo surgery or any invasive medical procedure, it is important to inform your doctor about all of the supplements and medications you are taking, including Curcumin, Piperine as they may need to be temporarily discontinued to prevent excessive bleeding during the procedure.

Precautions

There is limited data on the safety of this supplement during pregnancy or breastfeeding, so it is generally recommended to avoid them or speak with your doctor before taking them. Curcumin and piperine have been shown to have blood-thinning effects, which means it can reduce blood's ability to clot. It mainly interacts with medications that are also blood thinners, such as warfarin, aspirin, clopidogrel, and others. If you take any blood-thinning medications, speaking with your healthcare professional before starting the treatment is important. Your healthcare professional may need to adjust your medication dosage or monitor your blood clotting time more closely to prevent serious interactions or side effects.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. This tablet is generally safe and won't cause serious side effects. However, consult your physician for advice if you experience any uncommon side effects.

Word Of Advice

Consult your doctor if you are pregnant or planning for pregnancy during the treatment. It is not known if Curcumin and piperine pass into the breast milk. Hence, breastfeeding during this treatment is not recommended. Keep the curcumin and piperine out of reach of children and store it in a cool, dry place. Do not exceed the recommended dosage, as high doses of other natural compounds in this tablet may cause gastrointestinal discomfort. It is highly advised to avoid or limit alcohol consumption while taking this drug because alcohol consumption may interfere with the absorption and effectiveness of the supplements and may also increase the risk of gastrointestinal side effects.

Frequently Asked Question

References

  1. Mariia Zadorozhna et al; Piperine: role in prevention and progression of cancer; Molecular Biology Reports; Published on Oct 2019; Accessed on 08/07/2021; https://pubmed.ncbi.nlm.nih.gov/31273611/
  2. Sharma RA et al; Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer; Clinical Cancer Research; Published on July 2001; Accessed on 08/07/2021 https://pubmed.ncbi.nlm.nih.gov/11448902/

Disclaimer

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.