Human rabbit anti-T cell immunoglobulin belongs to the therapeutic class of immunomodulators.

Human rabbit anti-T cell immunoglobulin treats severe acute graft-versus-host disease (GvHD) after allogeneic hematopoietic stem cell transplantation (HSCT).

Human rabbit anti-T cell immunoglobulin can be given by intravenous (IV) or intramuscular (IM) injection. The IV route is the most common route of administration. The doctor chooses the administration route based on the patient's individual needs and preferences.

 Human rabbit anti-T cell immunoglobulin can cause both common and serious side effects. Common side effects include fever, chills, nausea, vomiting, diarrhea, headache, muscle pain, fatigue, rash, and itching. Serious side effects include allergic reactions, low blood counts, infection, kidney problems, liver problems, pneumonitis, pulmonary edema, thrombosis, and death.

Human rabbit anti-T cell immunoglobulin can cause allergic reactions, low blood counts, infection, kidney problems, liver problems, pneumonitis, pulmonary edema, thrombosis, and death. It can deplete the body's white blood cells, red blood cells, and platelets. This can make people more susceptible to infection, anemia, and bleeding.

People with a history of allergic reactions to Human rabbit anti-T cell immunoglobulin or other monoclonal antibodies should not receive hrATG. People receiving it should be monitored for signs and symptoms of low blood counts, such as fever, chills, fatigue, shortness of breath, and easy bruising or bleeding. People receiving it should be monitored for signs and symptoms of infection, such as fever, chills, cough, shortness of breath, and urinary tract infection.

Talking to your doctor about these risks and benefits before taking Human rabbit anti-T cell immunoglobulin is important, as it can cause low blood counts, infection, kidney problems, liver problems, pneumonitis, pulmonary edema, thrombosis, and death. It can cause low blood counts, so it is important to have your blood counts monitored regularly. This will help your doctor to identify any problems early on and take steps to correct them.  It is important to take precautions against infection as it can weaken your immune system. This includes washing your hands frequently, avoiding people who are sick, and getting vaccinated against common infections. If you experience hives, itching, rash, shortness of breath, swelling of the face, tongue, or throat, and difficulty breathing, seek medical attention immediately.

1. Athina L. Yoham, Damian Casadesus, [Revised on 27th May 2021] [Accessed on 13th September 2023], https://www.ncbi.nlm.nih.gov/books/NBK557884/
2. CSL Behring GmbH, [Revised on Jun 2019] [Accessed on], https://www.medicines.org.uk/emc/files/pil.6791.pdf
3. CSL Behring (NZ) Ltd, [Revised on Jun 2021] [Accessed on  13th September 2023]https://www.medsafe.govt.nz/profs/Datasheet/r/RhDimmunoglobulinVFinj.pdf
4. Neovii Biotech GmbH, [Revised on Jun 2019] [Accessed on 13th September 2023], https://www.hpra.ie/img/uploaded/swedocuments/448358b2-4de2-44fb-b89b-bf36f9f87182.pdf

The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.