This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
The U.S. FDA approved insulin glargine in April 2000 for treating diabetes mellitus.
Mechanism of Action of undefined
Insulin glargine involves providing a slow and consistent release of insulin to mimic the basal insulin secretion in individuals with diabetes. This helps regulate blood glucose levels, prevents hyperglycemia, and reduces the risk of hypoglycemia, contributing to better management of diabetes.
Uses of undefined
Insulin glargine is used to treat both type 1 and 2 diabetes mellitus in adults and pediatric patients.
undefined Drug administaration and Dosage available
Insulin glargine is available as a 100IU/ml injection which is administered under the skin by your doctor. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Warnings, Precautions and Side Effects of undefined
Warnings
It is not recommended for diabetic ketoacidosis patients. Inform your doctor if you have a liver, kidney problem, obese(overweight), or acute illness, edema or sodium retention, eye problem, low blood pressure and allergic to Insulin glargine or any of its ingredients Elderly patients should be cautious while taking the medicine.
Precautions
Your doctor will advise you to monitor your blood pressure while under medication. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding.
Side Effects
The common side effects that are experienced while you are on the treatment with insulin glargine, hypoglycaemia (low blood sugar), weight gain, allergic reactions, skin thickening or pits at the injection site swelling.
Word Of Advice
It is advised to avoid drinking or limiting your consumption to avoid undesirable side effects. It may increase or decrease your blood sugar level, when you are under medication. Consult your doctor before driving or when to start driving while taking medicine, as it may after your driving ability, it is recommended to be cautious. Inform your doctor if you are allergic to sodium as this medicine may contain sodium as an ingredient.
Frequently Asked Question
References
- Sanofi-Aventis, Electronic Medicines Compendium (EMC), [Revised on Apr 2023] [Accessed on 10 Oct 2023], https://www.medicines.org.uk/emc/files/pil.13280.pdf
- Sanofi-Aventis, US Food and Drug Administration, FDA [Revised on July 2015] [Accessed on 10th Oc 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021081s072lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Endocrine pancreas and pharmacotherapy of diabetes mellitus and hypoglycemia,12th edition, 2011, 1250-1252.
- KD Tripathi, Essentials of Medical Pharmacology, Insulin, oral hypoglycemic drugs and glucagon, 7th edition, 2013, 259-270.
Disclaimer
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details consult your doctor about your medical condition to know if you are eligible to receive this treatment.
