This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Melatonin belongs to the pharmacological class of hormones and synthetic substitute
Mechanism of Action of undefined
Melatonin's mechanism of action centers on its role in regulating the circadian rhythm, where it is produced in response to decreasing light levels, inducing drowsiness and signaling the body's readiness for sleep. It also influences body temperature hormone release, and possesses antioxidant properties. Its impact extends to various bodily systems through its receptors. Still, its primary function remains in synchronizing the sleep-wake cycle, making it a key factor in managing sleep-related issues.
Uses of undefined
Melatonin is commonly used to manage sleep-related issues and regulate the sleep-wake cycle. It is often employed to alleviate insomnia, improve sleep quality, and address disturbances caused by jet lag or shift work. This medication mimics the body's natural production of this hormone, helping individuals fall asleep faster and adjust their sleep patterns.
undefined Drug administaration and Dosage available
Melatonin is typically taken orally. It comes in various forms, including tablets, capsules, gummies, and liquid drops, all designed to be ingested by mouth. The exact route of administration will depend on the specific form of this medication you are using. It's important to follow the dosing instructions provided on the product's packaging or as your healthcare provider recommends.
Warnings, Precautions and Side Effects of undefined
Warnings
Improper dosing or timing of melatonin may disrupt the natural sleep-wake cycle or worsen sleep disorders. While rare, severe allergic reactions to this medication, such as skin rash or difficulty breathing, can occur. Prolonged or excessive use of this medication may lead to dependency or affect its natural production. Its effects on hormones may impact certain medical conditions, such as hormone-sensitive cancers. The production of this medication is influenced by light exposure. Excessive light exposure at night or taking this medication in a bright environment may affect its efficacy.
Precautions
Follow proper dosing and timing guidelines to avoid disruptions in the sleep-wake cycle. Consult a healthcare provider if you experience worsened sleep patterns or existing sleep disorders. Those with underlying health conditions like liver, kidney, or seizure disorders should seek medical guidance. Hormone-sensitive conditions, pregnancy, and breastfeeding require consultation with healthcare providers. Managing light exposure and individual variability is crucial, warranting medical attention if unexpected reactions arise.
Side Effects
Melatonin may lead to side effects such as daytime drowsiness, headaches, upset stomach, mood changes, and disruptions to the sleep-wake cycle. While these effects are generally mild and transient, rare allergic reactions with symptoms like skin rash, swelling, or difficulty breathing can occur. Its impact can vary among individuals, and serious side effects like lowered blood pressure or interactions with medications are possible. It is advisable to consult a healthcare provider before use, particularly if you have underlying health conditions or are taking other medications.
Word Of Advice
Consult a healthcare provider before use, especially if pregnant, breastfeeding, or with underlying health conditions; adhere to recommended dosages and timings, particularly for short-term use; be mindful of potential allergic reactions, drug interactions, and drowsiness when driving or operating machinery; avoid alcohol while taking melatonin; prioritize age-appropriate dosing for older adults, children, and adolescents; recognize individual sensitivity and adjust dosing if necessary; ensure proper evaluation of underlying sleep disorders before use; consult a healthcare provider if dealing with hormone-sensitive conditions, cancer, or other health concerns; be aware of potential withdrawal or dependency with long-term use; consider light sensitivity and promote a sleep-conducive environment; stay informed about potential interactions with other sleep aids or medications; tailor usage to your health profile and explore non-pharmacological sleep improvement strategies alongside this medication Always prioritize professional guidance for safe and effective use of this medication.
Frequently Asked Question
References
- Elena Benelli et al.; A Combined Therapy with Myo-Inositol and D-Chiro-Inositol Improves Endocrine Parameters and Insulin Resistance in PCOS Young Overweight Women; Published on 14/07/2016; Accessed on 11/08/2023; https://www.ncbi.nlm.nih.gov/pubmed/27493664
- Colonies Pharma Ltd, Electronic medicines compendium (EMC) , [Revised on05 Oct 2021] [ Accessed on 10th August 2023],https://www.medicines.org.uk/emc/product/10405/smpc#gref
Disclaimer
The drug information on this page is not a substitute for medical advice, it is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.