Uses of undefined

Thalidomide is used to treat moderate to severe leprosy in combination with dexamethasone and is indicated for treating patients with newly diagnosed multiple myeloma. It is also indicated as maintenance therapy for the prevention and suppression of the cutaneous manifestations of erythema nodosum leprosum (ENL) recurrence. Thalidomide is also sometimes used to treat certain skin conditions involving swelling and irritation.

undefined Drug administaration and Dosage available

Temozolomide is a prescription drug available as an oral capsule. The drug will be prescribed by the healthcare professional. Your physician will determine the medicine's dose, dosage form, and frequency. Take the capsule as a single dose at bedtime. Swallow the capsule whole with water. Avoid crushing or chewing the capsule. Wash your skin carefully with soap and water in case of contact with a broken capsule. 

Warnings, Precautions and Side Effects of undefined

Warnings

If thalidomide is taken during pregnancy, it can cause severe birth defects or embryo-fetal death. It should never be used if you are pregnant, suspecting to be pregnant, or trying for pregnancy. Even one capsule regardless of its strength, taken during pregnancy can cause severe harmful effects on the fetus. Inform your physician if you are pregnant during the treatment or planning to get pregnant.  Increased risk of deep vein thrombosis and pulmonary embolism in patients with multiple myeloma taking thalidomide with dexamethasone.

Precautions

This drug may reduce the effectiveness of oral contraceptives; using two reliable methods of contraception is necessary. The drug may cause allergic reactions; notify your doctor if you see any signs of rash, itchy skin, redness, Swelling of your lips or tongue, sudden cough, and low blood pressure.  Inform your physician if you have any kidney disease, liver disease, lung disease, blood/bleeding problems, or infection and about all the other prescribed, over-the-counter medicines, vitamins, nutritional supplements, or herbal medications you take. Avoid consuming alcohol while taking Thalidomide. Female patients with reproductive potential should take pregnancy tests frequently. Avoid consuming alcohol or operating heavy machinery after taking this medication. 

Side Effects

The common side effects of thalidomide are sleepiness, rashes, headache, dizziness, impotence, decreased energy or strength, pain, tenderness, low calcium, and blood count levels, swelling of hands and feet, constipation, numbness or tingling sensation, nausea, and reduced appetite, anxiety, depression, confusion and mood swings, fever, weight loss or weight gain, indigestion, vomiting, dry mouth, muscle cramps, blurred vision, ear problems, and kidney damage. Other serious effects include nerve damage, decreased blood pressure, low WBC count, slow heartbeat, serious allergic reactions, tumor lysis syndrome, sudden pain in the chest or difficulty breathing, pain and swelling in the legs, and bleeding or bruising without injury.

Word Of Advice

Women who are pregnant or suspect they may be pregnant should not use this medication. Hence, it is advised to use effective birth control for at least 4 weeks before beginning treatment, during treatment, and at least 4 weeks after stopping Thalidomide treatment. Handle this medication with disposable gloves since it may come into contact with the skin. It is advised to refrain from donating blood or sperm both during treatment and for seven days after treatment with this drug.

Frequently Asked Question

• Can children use Thalidomide?
• No, Thalidomide is not recommended for usage in children under 18.

• Can I drink alcohol while taking Thalidomide?
• Drinking alcohol while taking Thalidomide may cause sleepiness. Hence alcohol should be avoided with this medication.

• What is the best time to take Thalidomide? 
• It is best to take Thalidomide once a day at bedtime, one hour after dinner. This will make you less likely to feel sleepy at other times.

• What happens if I miss my Thalidomide dose?
• Take the recommended dose if you miss a Thalidomide dose by less than 12 hours. If you miss this dose by more than 12 hours, skip the missing dose and start your next dose at the regular time.

• Is it safe to father a child while taking Thalidomide?
• It is not safe to father a child while taking Thalidomide because this medication passes into the semen, which leads to severe birth defects in the unborn baby.

• Can I donate my blood while taking Thalidomide?
• You should not donate blood while taking Thalidomide during treatment and four weeks after discontinuing this medication. Because the donated blood might be given to pregnant women as it causes birth defects in the unborn baby.