Blood Group and Diabetes Risk: What You Need to Know
23 Aug 2024
8 mins
Can your blood group type help predict diabetes? An essential guideDo you think your blood's only role is to transport vital oxygen and nutrients throughout your body? It might surprise you to know that certain blood types can increase the risk of developing diabetes. While we all know traditional risk factors such as diet, genetics, physical inactivity, cholesterol, and blood pressure, understanding your blood group type might present a new perspective on predicting, preventing, and managing this condition.    IS DIABETES CONSIDERED A SILENT KILLER?   Diabetes mellitus is a metabolic disorder characterised by elevated glucose levels (blood sugar) in the body. This condition often leads to various side effects and long-term health complications. Insulin, a hormone crucial for transporting sugar from the bloodstream into your cells for energy, is either produced in insufficient amounts or not effectively utilised in diabetes. As a result, glucose remains in the blood rather than being used by the cells, leading to persistent high blood sugar levels.   WHAT ARE THE COMMON SYMPTOMS OF DIABETES? The symptoms of diabetes [https://www.mrmed.in/health-library/diabetes/common-side-effects-of-diabetes] include    * Frequent urination * Numbness or tingling in your hands or feet * Unexplained weight loss * Blurred vision * Fatigue * Dry mouth and increased thirst * Slow-healing of sores or cuts * Frequent skin and vaginal yeast infections   WHAT IS THE LINK BETWEEN BLOOD TYPE AND DIABETES RISK?   Blood type, determined by the ABO and RhD systems, could be more important in your health than you might think. Your blood group might affect how your body handles glucose and insulin, the hormones responsible for regulating blood sugar levels [https://www.mrmed.in/health-library/health-care/know-your-blood-sugar-numbers]. According to recent research, different blood types may be connected with an increased or decreased risk of developing type 2 diabetes [https://www.mrmed.in/health-library/diabetes/prevention-type-2-diabetes].   WHICH BLOOD GROUP IS PRONE TO DIABETES?   While blood type may play a role, it is a minor factor compared to well-known risk factors like diet, exercise, and genetics. A study [https://link.springer.com/article/10.1007/s00125-014-3472-9] conducted by researchers from INSERM and affiliated institutions found that   * Women with blood type "A" are 10% more likely to develop type 2 diabetes than those with blood type "O." * Women with blood type "B" had a 21% higher risk of developing type 2 diabetes than those with blood type "O." * Blood type "O" is linked to reduced levels of insulin resistance, which is a major risk factor for diabetes.   This is because blood type “O” has lower levels of insulin resistance, which is a crucial factor in developing diabetes. However, this study was conducted on females. These results may or may not apply to men.   WHICH BLOOD GROUP IS INSULIN RESISTANT?   Insulin resistance is a complex condition where your body’s cells don’t respond properly to insulin, which can lead to increased blood glucose levels.   Research [https://www.actamedicamediterranea.com/archive/2017/medica-6/there-is-a-relation-between-blood-subgroups-and-insulin-resistance/document] conducted at Kayseri Training and Research Hospital indicates that.    * Blood type "A" is more prone to insulin resistance. * Blood type "O" is less prone to insulin resistance. * Blood type A Rh(+) shows a significantly higher prevalence of insulin resistance.   This study identifies a link between blood types and insulin resistance. This might be due to the way certain blood types interact with insulin and glucose metabolism.   WHAT ARE THE RISK FACTORS FOR DIABETES?   The risk factors for diabetes are important in the prevention and management of the condition. The risk factors include   * Genetics * Auto-immune conditions * Exposure to viruses such as Enteroviruses and Rubella Virus * Age * Obesity [https://www.mrmed.in/health-library/cancer-care/obesity-symptoms-side-effects] * Physical inactivity * Blood pressure [https://www.mrmed.in/health-library/hypertension/low-blood-pressure-causes-effects-heart]   IS BLOOD GROUP A RISK FACTOR FOR DIABETES?   A comprehensive approach is essential when evaluating diabetes risk. While certain blood groups can be a risk factor, they should not be the only focus. Diabetes risk is significantly influenced by lifestyle factors such as a good diet [https://www.mrmed.in/health-library/health-care/benefits-of-eating-healthy], regular exercise, and weight management. The blood group is just one piece of the puzzle.    BLOOD GROUP-RELATED HEALTH COMPLICATIONS   A study published in the Journal of Thrombosis and Haemostasis [https://onlinelibrary.wiley.com/doi/full/10.1111/jth.12507] found that people with blood type “AB” have nearly double the risk of stroke [https://www.mrmed.in/health-library/heart-care/stroke-causes-types-symptoms-treatment] compared to those with blood type O. This research, part of the REGARDS Study, involved over 30,000 participants and linked to higher stroke risk in non-diabetic individuals with blood type AB.  CAN BLOOD GROUPS HELP IN DIABETES PREVENTION? While knowing your blood type might offer some insights into your diabetic risk, it should be part of a broader prevention plan. Maintaining a healthy lifestyle [https://www.mrmed.in/health-library/diabetes/diabetes-exercise-diet-lifestyle] is the most efficient way to reduce the risk of diabetes. This includes regular physical activity, a balanced diet, and maintaining a healthy weight. Making certain lifestyle changes can significantly reduce the risk of diabetes, such as   1. Maintain a healthy weight: Weight loss can reduce the risk of diabetes. To prevent the condition from progressing, the American Diabetes Association advises prediabetics to lose 7% to 10% of their body weight. Being obese [https://www.mrmed.in/health-library/health-care/world-obesity-day] can double the risk of diabetes.  2. Physical activity: Has various benefits, such as   * Lower your blood sugar levels * Reduce weight * Boost your sensitivity to insulin — which helps regulate blood sugar within a normal range.   3. Healthy diet: Eating a diet that is rich in proteins and minerals not only helps with diabetes but also enhances the overall well-being of an individual.  Consider a fibre-rich diet, which can help in   * Reducing the absorption of fat and cholesterol * Slowing down the absorption of sugar and reducing blood sugar levels * Managing Inflammation and Blood Pressure to Improve Heart Health [https://www.mrmed.in/health-library/heart-care/how-to-keep-heart-healthy] Stay away from "bad carbohydrates" such as processed meals, food that is rich in sugar, white bread, pastries, and fruit juices.   It is important to begin with regular screenings if you want to take charge of your diabetes risk. Make an appointment for a blood sugar test with your healthcare provider as soon as possible if it has been a while since your last checkup. Diabetes may be managed and prevented effectively with early detection.  CAN BLOOD GROUPS HELP IN DIABETES TREATMENT?   Knowing your blood type can be beneficial when treating diabetes. It can help tailor certain treatment strategies or provide an overview of how you might respond to different medications. However, treatment decisions should always be made after discussing with healthcare professionals.   PERSONALISED TREATMENT APPROACHES Personalised treatment approaches optimise diabetes management by considering various factors, including blood type. For example, individuals with different blood types might respond differently to certain medications or dietary interventions.    Knowing your blood type can help healthcare professionals to make more accurate choices regarding your treatment plan.   WHAT IS THE ROLE OF THE DOCTOR IN DIABETES? Healthcare professionals play an important role in managing diabetes. They can personalise your treatment plan based on an evaluation of your health condition, including blood type, lifestyle factors and medical history. Working with your healthcare team can help in effective treatment and support for managing diabetes.   PROFESSIONALS INSIGHTS   Dr. Kotwal says, “The call for action for a 20-year-old male whose waist circumference is more than 80 centimetres and for a woman whose waist circumference is more than 90 centimetres, or if there is one family member with diabetes, that family member could be a father, mother, or a relative, is to get screened. If both parents are diabetic, the risk is 90%, and if one parent is diabetic, it is 70%. On the other hand, if one relative is diabetic, the risk is 40%.”   Dr Kotwal states, “One factor which really impacts is weight gain. After 10 years of age, individuals exceeding the 85th percentile are considered overweight, and those surpassing the 95th percentile are classified as obese. All these individuals are at risk of developing diabetes,” FREQUENTLY ASKED QUESTIONS (FAQS)   1. Is blood type O safe from diabetes?   Individuals with blood type O have a lower risk of developing diabetes when compared with blood groups A and B.   2. What is the most common blood type for diabetics?   Blood type A might be associated with a higher risk of developing type 2 diabetes compared to blood type O, which is linked to a lower risk. However, blood type is just one factor among many that influence diabetes risk.   3. Is blood type O the healthiest?   Blood type O has a decreased risk of developing heart conditions and diabetes when compared to blood types A and B.     4. Can blood groups prevent diabetes?   No, blood groups cannot prevent diabetes, but certain blood types like A and B can increase the risk of acquiring diabetes.    5. What diseases are associated with blood type O?   The blood type has an increased incidence of plague, tuberculosis,  and cholera. WRAPPING UP   While blood type influences diabetes risk, it should not be the primary focus. Studies have shown that blood types such as A and B might have an increased risk of developing insulin resistance and diabetes, while blood type O has less risk compared to both.    Ultimately, maintaining a healthy lifestyle—through a balanced diet, regular exercise, and weight management—is crucial in reducing diabetes risk. Regular screenings and consultations with doctors are essential for early detection and personalised treatment. Blood type knowledge can complement traditional methods but should not replace standard preventive measures and treatments.   REFERENCES   1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621172/ [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621172/] 2. https://pubmed.ncbi.nlm.nih.gov/3142337/ [https://pubmed.ncbi.nlm.nih.gov/3142337/] 3. https://pubmed.ncbi.nlm.nih.gov/13304326/ [https://pubmed.ncbi.nlm.nih.gov/13304326/] 4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712191/ [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712191/] 5. https://ashpublications.org/blood/article/115/23/4635/27755/The-relationship-between-blood-groups-and-disease [https://ashpublications.org/blood/article/115/23/4635/27755/The-relationship-between-blood-groups-and-disease]   Note: The information provided in this blog is intended for general knowledge. It is important to remember that it should not replace professional medical advice. If you have any concerns about diabetes or related symptoms, please consult a healthcare provider.
Dr Deva Prasath S
How to manage diabetes with life style changes
5 Jun 2024
5 mins
5 Best Approaches to Managing Diabetes: Diet, Exercise, and MoreDiabetes is a commonly occurring condition in most people these days. In diabetes, the blood sugar (glucose) level in an individual’s body is higher than normal. Diabetes occurs when the pancreas fails to produce enough amount of insulin or doesn’t make any at all. It may also occur if the body of the patient does not respond to insulin properly. There are two major forms of diabetes [https://www.mrmed.in/health-library/diabetes/world-diabetes-day]: Type 1 diabetes and Type 2 diabetes. Both of these common types of diabetes are lifelong conditions that require proper treatment and management.   Type 1 Diabetes: This type of diabetes is an autoimmune condition in which the immune system acts on the insulin-producing cells in the pancreas and destroys them. As a result of the immune system attack, the pancreas produces little or no insulin. Type 1 diabetes is also known as insulin-dependent diabetes.    Type 2 Diabetes: This type of diabetes is the most common type of diabetes. A person is diagnosed with type 2 diabetes when their body fails to produce sufficient insulin or when the body fails to respond to the insulin in the body. The risk of developing type 2 diabetes [https://www.mrmed.in/health-library/diabetes/prevention-type-2-diabetes] is high in the following people,    * Who are obese * Leading a sedentary lifestyle * Eating processed foods, sugary foods, saturated fats and high-carbohydrate foods * Taking certain medications like corticosteroids (long-term use) * Having certain hormonal disorders like hypothyroidism * Having chronic stress * Lacking quality sleep   TREATMENT FOR DIABETES    The treatment for diabetes depends on the type of diabetes, age, and overall health of the patient. Treatments for diabetes management [https://www.mrmed.in/health-library/diabetes/common-side-effects-of-diabetes] include a combination of blood sugar monitoring, medications or insulin, and healthy lifestyle changes such as a diabetic diet and exercise.    WHY ARE LIFESTYLE CHANGES FOR DIABETES IMPORTANT?   Diabetes is a chronic lifelong condition. When not managed properly, diabetes can pose a serious risk to health. Hence, healthy lifestyle changes for diabetes are important to manage the condition in the long run, prevent the risk of other conditions and have an improved quality of life. People with type 1 diabetes and type 2 diabetes may experience symptoms like increased thirst, fatigue, frequent urge to pee, dry mouth, weight loss, etc.    If diabetes is not managed well, in the long term, it may increase the patient’s risk of developing various other conditions. Hence, along with proper medications, lifestyle changes for diabetes are also needed. Some of the complications that can occur due to diabetes include:   1. Cardiovascular diseases, such as stroke, atherosclerosis, coronary artery disease, and heart attack 2. Nephropathy that can cause kidney failure or the need for a kidney transplant. 3. Kidney problems requiring dialysis 4. Diabetic Retinopathy (eye damage) 5. Diabetic Neuropathy (nerve damage) 6. Skin and mouth conditions 7. Hearing loss 8. Foot damage 9. Sexual dysfunctions 10. Gastroparesis 11. Mental health problems   LIFESTYLE CHANGES FOR DIABETES MANAGEMENT    5 strategies to help you manage your diabetes better!   While medications, insulin therapy, and blood sugar monitoring are important to manage your diabetes, they cannot be effective if you don’t make healthy lifestyle changes. To manage your diabetes, reduce the risk of developing other health complications, and improve the quality of your life, and it is important to follow a healthy lifestyle along with your doctor-prescribed treatment. Here’s a list of 5 lifestyle changes that can help you manage your diabetes well,    1.  A DIABETIC DIET  A diabetic diet [https://www.mrmed.in/health-library/diabetes/diabetic-diet-plan] may sound fancy, but it is not what it sounds like. A diabetic diet, in simple terms, is a list of foods that you must and must not eat with diabetes. Even in the case of a non-diabetic patient, the food they eat affects their blood sugar levels in the body, let alone in a person with diabetes. Individuals with diabetes have to eat more mindfully to ensure their blood sugar levels are in check.    Because what you eat has a direct effect on your blood sugar levels. Controlled portion sizes and healthy foods make up for the most important aspects of a diabetic diet. But, with the availability of so many options, finding the right foods to eat with diabetes may be challenging. Hence, it is best to consult a dietician to understand what your body needs if you have diabetes. Your dietician will provide you with the right diet chart, depending on your case, to ensure your health is not compromised.    In general, individuals having diabetes must include the following foods in their diabetic diet,    * Plenty of vegetables * Foods high in fiber, like legumes, chickpeas, vegetables, and whole grains * Healthy fats like walnuts, flax seeds, extra virgin olive oil, etc * Whole-grain foods * Fat-free /low-fat yogurt, milk, and cheese * Protein-rich foods like beans, lentils, lean meat, and seafood   LIST OF LOW GLYCEMIC INDEX (GI) FOODS TO EAT IN DIABETES    Foods that have a low Glycemic Index (GI) cause gradual release of glucose in the bloodstream and help regulate blood sugar levels.   * Spinach * Yogurt * Cabbage and cauliflower * Barley * Lentils * Chickpeas * Nuts and Seeds * Curd * Tomatoes   Foods to avoid if you have diabetes include the following,   * Foods rich in sugar like ice creams, desserts, sugar-rich cereals * Foods with a high glycemic index (GI), such as white rice and potatoes * Processed foods like packaged items (chips and biscuits) * Processed red meat * Foods rich in saturated fats * Alcoholic beverages * Foods high in sodium * Trans fats * Refined carbohydrates such as pasta, pastries, and white bread   2.  EXERCISING REGULARLY    A very powerful way of managing weight and diabetes is exercising. Exercising regularly helps in improving insulin sensitivity, lowering blood sugar levels, and managing weight. To manage diabetes, a gym or high-intensity workout is not necessary. A normal every day workout of 30 minutes daily is enough.    If you have diabetes, then you can add physical activity to your everyday life by incorporating exercises like walking, jogging, yoga, or cycling. As a diabetic patient, your aim should be to add at least 150 minutes of exercise in a week. Regular exercising will also reduce your risk of getting heart disease and will help you manage stress better.   3.  MANAGE STRESS   One of the most common risk factors for various health conditions is stress. When you are stressed, the blood sugar levels in your body shoot up. Stress can make it difficult to manage diabetes. Hence, an important strategy for effective management of diabetes is stress management. Additionally, stress also impacts sleep and mental health, both of which can make diabetes worse.    To manage and relieve stress, you can practice yoga and deep breathing exercises, enjoy your favorite hobby, journal, listen to music, or meditate. If you are extremely stressed, then it is best advised to seek help from a professional such as a counselor or a psychologist to understand the root cause of your stress better and address it to improve your mental health.    4. MAINTAIN A HEALTHY WEIGHT    Obesity or overweight is a huge risk factor for developing type 2 diabetes. Being overweight also increases the risk of developing heart disease. To maintain a healthy weight, a combination of a diabetic diet, exercise, and stress management is required. Avoid alcohol consumption and quit smoking, as both of these habits can further worsen diabetes and your overall health.    5. QUALITY SLEEP   One of the most overlooked aspects of diabetes management is quality sleep. A study revealed that quality sleep is essential [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10693913/#:~:text=Sleep%20is%20essential%20for%20controlling%20how%20the%20body%20uses%20glucose,developing%20diabetes%20and%20insulin%20resistance.] to control how our body uses glucose. A poor quality of sleep can not only worsen type 2 diabetes but also increase the risk of developing insulin resistance, restless leg syndrome (RLS), sleep apnea, and insomnia. Sleep also increases stress, causes hormonal imbalance, and worsens metabolism. Hence, to manage diabetes effectively, quality sleep is essential. To improve the quality of your sleep, you can follow the below-mentioned tips:   1. Avoid using electronic devices like laptops and computers at least 2 hours before you go to sleep. 2. Read books before you sleep to relax 3. Avoid consuming any stimulants at night, such as caffeinated beverages 4. Make your environment comfortable for a good sleep 5. Avoid heavy evening workouts before you sleep 6. Practice going to bed at the same time every night and waking up at the same time in the morning. 7. Avoid drinking alcohol around your bedtime.   TAKE AWAY   Being diagnosed with diabetes can be stressful and life-changing. Especially when you know it is a lifelong condition. However, having diabetes doesn’t mean you cannot lead a healthy life. With proper care, treatment, and precautions, you can manage your diabetes effectively. To ensure you manage your condition well, ensure to see your doctor regularly, take your prescribed medications on time, be consistent with your blood sugar monitoring, and make healthy lifestyle changes.    The prognosis of diabetes may vary from patient to patient, depending on various factors. The factors determining the outlook (prognosis) of diabetes include the type of diabetes, the age of the patient at the time of diagnosis, how long the patient has had diabetes, overall patient health, how well the condition is managed, and if the patient has developed any complications. 
Arwa Aliakber
Semaglutide Diet Plan
12 Jan 2024
8 mins
Semaglutide Diet PlanUnderstanding what to eat and when to eat when you are on medication can be tricky. Your meal timing, size, and the types of foods and drinks consumed can all affect your body's response to a medicine. Food-related dosing instructions for medicines vary greatly and are not the same for all medications. So, if you are currently on semaglutide medication [https://www.mrmed.in/molecule/semaglutide], you may wonder: "Will my diet affect the drug's effectiveness and increase my chances of experiencing uncomfortable side effects? Will it help for weight loss?" The answer may be yes. Look below on this blog to discover an ideal diet for semaglutide to improve blood sugar profiles while minimizing adverse side effects.   HOW DOES SEMAGLUTIDE WORK?   Semaglutide is a diabetic medication used to improve blood sugar control in type 2 diabetes [https://www.mrmed.in/health-library/diabetes/prevention-type-2-diabetes] and aid in weight management in individuals with obesity or overweight. To recognize the possible interaction between semaglutide and your diet, familiarizing yourself with the semaglutide's mechanism of action will be helpful. And here's what you need to know: semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Thus, it functions similarly to the endogenous hormone GLP-1, which:   * Stimulates insulin release and inhibits glucagon secretion, which helps regulate blood sugar levels. * Slows down gastric emptying, prolonging feelings of fullness and aiding in better blood glucose control. * Acts on the brain's appetite regulation areas, particularly the satiety center in the hypothalamus, to reduce appetite.   IS THERE AN IDEAL SEMAGLUTIDE DIET?   Semaglutide is an anti-obesity medication, which, when taken as a 2.4 mg weekly subcutaneous injection combined with a low-calorie diet and exercise, typically leads to an average weight loss of 9.6% to 17.4% [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807016/] of initial body weight in patients. As mentioned above, semaglutide basically simulates the action of a naturally occurring hormone, GLP-1, in your body helping in weight loss. Also, there is little risk of a food-drug interaction. So, what should you eat while taking semaglutide? While, there isn't a "special diet" for semaglutide, but there are a few tips that you could follow:   * To minimize semaglutide's adverse side effects [https://www.mrmed.in/health-library/diabetes/side-effects-of-semaglutide] and, * Boost its effectiveness in controlling your blood sugar levels. [https://www.mrmed.in/health-library/health-care/know-your-blood-sugar-numbers]   I. FOOD TO EAT WHILE ON SEMAGLUTIDE   While on semaglutide, adapting your diet is key. While there's no strict 'semaglutide diet,' following general healthy eating principles enhances the medication's effectiveness in managing blood sugar levels and weight loss. Here's what to focus on:   * Carbohydrates: Opt for complex carbohydrates like brown rice, oats, quinoa, and wholemeal spaghetti. These are digested slowly, causing a gradual rise in blood sugar. Aim to have these make up a quarter of your plate. * Proteins: Include protein in every meal to reduce blood sugar spikes and increase fullness, preventing overeating. Good protein choices include plant proteins, pork loin, lean beef, skinless chicken, and white fish. About a quarter of your plate should consist of protein. * Fiber: Fill half your plate with vegetables and fruits. They are high in fiber, which slows down carbohydrate absorption and boosts satiety. Remember, while limiting fatty foods is a start, a balanced approach to your diet will support your diabetes management while on semaglutide.   II. FOODS TO AVOID WHILE ON SEMAGLUTIDE   When taking semaglutide, it is advisable to avoid fatty foods. This is because fat naturally slows down gastric emptying, and when combined with semaglutide's impact on digestion, it can lead to food moving too slowly through your digestive system. This might result in unpleasant and sometimes painful gastrointestinal problems such as nausea, vomiting, bloating, and upper abdominal cramping. Avoid highly processed foods. These often contain refined sugars, unhealthy fats, and excess salt, which can spike your blood sugar. For those who love street fast foods, be mindful of high-fat dishes. The key here is moderation – aim to limit these foods rather than completely cutting them out of your diet.   MASTERING SEMAGLUTIDE: TOP TIPS FOR BEST RESULTS   To maximize the effect of semaglutide in guiding weight loss, you may need to follow a few tips mentioned below to get your results:   1. Opt for Smaller, Frequent Meals: Semaglutide slows down the digestive process, so avoiding overeating is a good idea. Instead, break your daily food intake into smaller, more frequent meals. This can help prevent uncomfortable gastrointestinal symptoms like bloating and indigestion. 2. Stay Hydrated: Since semaglutide may lead to longer gastric emptying, staying well-hydrated is important. Adequate hydration is essential for preventing constipation resulting from dry, hard stools. A general guideline is to aim for around 30 mL of fluids per kilogram of body weight, although individual requirements may vary. 3. Allow Time Before Lying Down: To avoid reflux and indigestion, it's advisable to wait at least three to four hours after eating before lying down. This helps ensure that your stomach has had enough time to digest your meal. 4. Take semaglutide on an Empty Stomach: Semaglutide is taken as oral medication, and for it to be effective, you should take it on an empty stomach. Give the medicine at least 30 minutes to start working before eating, drinking, or taking other oral medications. Note that this advice doesn't apply to medications administered through injections.    HEALTHY HABITS TO FOCUS ON   It is important to keep up with other healthy habits even when taking semaglutide for diabetes management. Along with a balanced diet, these practices can boost the drug's effectiveness in controlling blood sugar as well as weight loss: 1. Regular Exercise: Aim for at least 20-30 minutes of moderate or 10 minutes of intense cardio daily, plus two days of strength training each week. 2. Stress Reduction: Techniques like meditation, deep breathing, and spending time with friends and family can help manage stress. 3. Quality Sleep: Get 7-9 hours of sleep every night. Stick to a regular sleeping schedule and avoid heavy meals before bedtime to improve sleep quality.   Final Notes   These tips can help you manage your diet effectively while taking semaglutide and minimize any potential discomfort or side effects associated with this medication. Always consult your healthcare provider or a registered dietitian for personalized guidance on managing your diet with semaglutide. Remember, everyone's body reacts differently to medications, and what works for one person might not work for another. Your healthcare team can provide the most accurate and personalized advice.   "Sweet in spirit, not in sugar - Thrive with diabetes, take control!"
Dr Vijayalakshmi
Side Effects Of Semaglutide
8 Jan 2024
8 minutes
Side Effects Of SemaglutideOPENING NEW DOORS IN DIABETES CARE AND WEIGHT CONTROL: THE SWEET SECRET BEHIND SEMAGLUTIDE   Certain advancements in the healthcare sector create excitement out of medical journals and make us realize the innovative world we live in! One such discovery is semaglutide. Semaglutide [https://www.mrmed.in/molecule/semaglutide] is a Glucagon-like peptide receptor agonist [GLP-1] that was initially approved for the treatment of diabetes mellitus, which later gained a red carpet welcome for its ability as a potential game changer in weight loss management. In June 2017, the FDA approved semaglutide in the management of diabetes mellitus; it was not too late to recognize its other true potential; in 2021, the FDA approved it for the management of weight loss. It quickly became the talk of the town among obese individuals and ultimately gained attention worldwide. Let's dive in and get some insights about this new horizon and, of course, the other side of the coin, the less spoken side effects this carries.   KNOW THE NUMBERS   As of now, semaglutide is effective in managing diabetes mellitus and obesity. The global prevalence of diabetes mellitus is about 422 million [https://www.who.int/health-topics/diabetes#tab=tab_1], responsible for at least 1.5 million direct deaths; as far as obesity is concerned, the prevalence is about 1 billion, [https://www.who.int/news/item/04-03-2022-world-obesity-day-2022-accelerating-action-to-stop-obesity#:~:text=More%20than%201%20billion%20people,they%20are%20overweight%20or%20obese.]and the values are expected to peak as Everest in upcoming years.   WORKING ACTION OF SEMAGLUTIDE   There is a naturally occurring amino acid peptide hormone in the intestinal cells of the body called glucagon-like peptide. Semaglutide is designed to mimic the action of this hormone and produce two specific actions.  1. Increased insulin release- In response to elevated blood glucose levels, semaglutide stimulates the pancreas to produce more insulin and plays a vital role in reducing blood glucose levels. 2. Cutting down the appetite: Semaglutide delays gastric emptying so that food stays longer in your stomach and reduces the urge to eat. It also acts in certain areas of the brain that regulate hunger and fullness. It is also said to be a silent aid in reducing cravings for sweets and contributes to reducing appetite.   WHO SHOULD TAKE SEMAGLUTIDE?   As mentioned, semaglutide is prescribed for type 2 diabetes mellitus management, but poses an upper hand in weight loss management in obese patients and  it is often exploited. Semaglutide is not for everyone. There is are classified criteria formulated in accordance with Body mass index [BMI] for usage: * Adults: 1. A BMI of 30 or greater 2. BMI of 27 or greater with at least one underlying health condition such as Type 2 diabetes mellitus [https://www.mrmed.in/health-library/diabetes/world-diabetes-day-2022], High blood pressure [https://www.mrmed.in/health-library/hypertension/high-blood-pressure-symptoms], Hyperlipidemia * Adolescents: Initial BMI at 95 percent or greater for the age and sex.   EXPLORING THE DARK CAVE: SIDE EFFECTS OF SEMAGLUTIDE   Semaglutide is mainly prescribed with the intention of adjuvant therapy for weight loss management [https://www.novo-pi.com/wegovy.pdf], along with reduced calorie intake and increased physical activity. Still, it is frequently considered and used as a sole treatment approach, making people take a pill and sit idle for weight loss, causing unwanted side effects.  Gastrointestinal side effects [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9631444/] are the most frequent and disturbing ones among semaglutide intake. Some of them include:   1. Nausea and vomiting : It is the most common side effect of people taking semaglutide. However, this is proportional to the dose you are taking and progresses as your doctor increases the dose rapidly. This condition improves over time as your body gets used to the drug.   2. Diarrhea: another common side effect you can experience during semaglutide is frequent diarrhea. However, it is mild and manageable.   3. Fatigue: Semaglutide reduces hunger, which aids in weight loss. Additionally, cutting back on calories may make you feel more exhausted. Fatigue should gradually go as your body adapts to any dietary changes you may make.   4. Gas, bloating, and burping: Another common side effect you may experience is a feeling of bloating, frequent burps, and gas. If left unnoticed they may develop as heartburn, acid reflux leading to GERD [https://www.mrmed.in/health-library/gastroenterology/heartburn-acidreflux-gerd-difference]. However, they can be settled with oral antacids and avoiding foods that provoke this cause.   5. Ozempic face: Taking semaglutide for weight loss can, of course, cause the desired effect, but the thing to note is that significant weight loss can also cause loss of facial fat. This tends to change the appearance of your face, causing it to look saggy and shrink, making you look older.   6. Weight rebound effect: Semaglutide is a long-term medication bound to be taken for longer periods to achieve the desired result; any discontinuation without your doctor's approval can cause a swirl in the body - rebound weight gain.   7. Low blood glucose: As mentioned, semaglutide is an antidiabetic drug that increases insulin secretion to lower blood glucose levels; combining it with other antidiabetic medications such as insulins and sulfonylureas, further decreases blood glucose, causing shaking and sweating.   8. Gallbladder diseases: Although not common, semaglutide can also cause gallstones, cholecystitis, and growth of tissues in the gallbladder.   MYTHS AND FACTS    Myth: You will lose weight by taking a pill without diet and exercise Fact: No, semaglutide is an adjuvant therapy. Along with a calorie deficit and proper physical activity, you will lose weight. It is not a magic pill. Myth: You can stop semaglutide once weight loss is achieved.  Fact: No, with proper consultation with your healthcare provider, it should be continued even if you achieve results since it may cause rebound weight gain. Myth: You should take semaglutide only if you have diabetes. Fact: Semaglutide can also be taken for weight loss management with suitable BMI values with or without having diabetes.   THE BOTTOM LINE   Semaglutide provides an upper hand in offering various advantages in weight loss therapy and management of diabetes mellitus; there is a need to watch out for side effects that accompany it. Although most side effects are manageable, others will subside after your body gets used to them. Despite these, the craze among the population for this thought to be a magic pill is skyrocketing. Always consider a healthcare professional to create a personalized treatment regimen before starting any therapy by yourself.                                                   Shed weight; Be healthy! 
Dr. Thamizhakaran K S
World Diabetes Day 2023
14 Nov 2023
10 mins
World Diabetes Day 2023"Less sugar means more happiness."   World Diabetes Day is annually observed on November 14th. This special day provides an opportunity to raise awareness among the public about diabetes, which is recognized as a global public health issue. People need to analyze how it impacts the future generation. We should take preventive measures to control diabetes in young and older individuals. In recent days, irrespective of age, gender, and other factors, most of us are affected by diabetes. On this world diabetes day, let's discuss diabetes and its impact on the people around us.   HISTORY OF WORLD DIABETES DAY   Every year, November 14 is commemorated as World Diabetes Day, which was initiated by the International Diabetes Federation along with the World Health Organization in 1991 to honor the birthday of Sir Frederick Banting, who is one of the discoverers of insulin. This year, we will celebrate and spread awareness with the theme of ‘Access to diabetes care’.   LET'S KNOW ABOUT DIABETES AND ITS IMPACT   Diabetes is a severe pancreas disorder, resulting in insufficient insulin production or the body cannot effectively use the insulin it produces. According to the IDF (International Diabetes Federation), [https://diabetesatlas.org/]537 million adults (1 in 10) were affected by diabetes in 2021, and it was expected to rise to about 643 million in 2030 and 783 million in 2045. We need to understand the prevalence of diabetes all over the world and protect our people from this sugar-coated enemy. TYPE OF DIABETES   The common types of diabetes that affect most people are given below:   * Type 1 diabetes (juvenile diabetes): Type 1 diabetes is the condition in which your body's immune system is raised against the insulin-producing cells in the pancreas. * Type 2 diabetes: Type 2 diabetes [https://www.mrmed.in/health-library/diabetes/prevention-type-2-diabetes] results in increased blood sugar levels, and it is known as adult-onset diabetes. * Gestational diabetes: Gestational diabetes [https://www.mrmed.in/health-library/diabetes/gestational-diabetes-mellitus] is caused when a pregnant woman's body can't make sufficient amounts of insulin. * Prediabetes: Prediabetes is characterised by an elevated blood glucose level which is higher than the normal value but not high enough to be diagnosed as type 2 diabetes. In general, diabetes can be categorized into two: diabetes mellitus and diabetes insipidus, which share the common symptoms of increased thirst and urination. But differences in blood sugar levels.   COMMON SYMPTOMS OF DIABETES   It is often considered a silent killer due to its symptoms, which everyone cannot identify. The symptoms of diabetes [https://www.mrmed.in/health-library/diabetes/common-side-effects-of-diabetes] may differ based on the type of diabetes and the patient's body condition. Some of the common symptoms are  * Frequent urination * Feeling thirsty * Sudden weight loss * Feeling hungry * Blurry vision * Feeling numb or tingling hands or feet * Feel very tired * Dry skin * Having sores that heal slowly * More prone to infections  6 RISK FACTORS OF DIABETES   1. Heart and blood vessel disease: High blood glucose level from diabetes increases the force of the blood and damages the artery walls and blood vessels. The most common heart diseases associated with diabetes [https://www.mrmed.in/health-library/diabetes/common-side-effects-of-diabetes]are angina, coronary artery disease, narrowing of arteries, and high blood pressure. 2. Nerve damage: Nerve damage or neuropathy is caused by an increase in glucose content in the blood, which injures the walls of tiny blood vessels or capillaries that supply the nerve. If this goes unnoticed, it may affect the digestive system and cause problems like nausea, vomiting, constipation, and diarrhea. 3. Kidney damage: If blood sugar is not maintained for a prolonged period of time, it completely blocks the action of kidneys so that it cannot remove wastes and excess fluid in the body. It leads to complete kidney failure. 4. Diabetic eye disorder:  High blood sugar level leads to blurry vision, cataracts, glaucoma, and retinopathy, and diabetes is the major reason of blindness in adults ages 20 to 74. 5. Foot damage: Nerve damage causes poor blood flow to the feet and increases foot complications. It starts with cuts and blisters, and if it is untreated, it leads to several infections that keep on spreading to the toe, foot, and entire leg. Advanced stages include surgical removal of affected areas. 6. Pregnancy complications: High blood glucose levels are dangerous for both the baby and the mother. Pregnancy complications include miscarriage, birth defects in developing babies, and difficulty in getting pregnant, which often occurs when diabetes is not well controlled.   TIPS FOR PREVENTING DIABETES   * Do regular exercise. * Focus more on weight loss if overweight. * Follow a healthy diet and include more fruits [https://www.mrmed.in/health-library/diabetes/prevention-type-2-diabetes] in your diet. * Quit or limit your smoking habit. * Identify the underlying cause as early as possible in the pre-diabetic stage. * Take less refined carbohydrates. * Consume fiber-rich foods.   BREAK THE MYTH AND KNOW THE FACT: TOP 8 MYTHS AND FACTS ABOUT DIABETES   Myth: Diabetes is contagious Fact: No, Diabetes is not a contagious disease that can be spread through saliva, blood, or any other medium. According to research, diabetes is categorized as a non-communicable disease.   Myth: Diabetes is a disease of old age Facts: Diabetes occurs most often in middle-aged and older people, but it can also affect children (juvenile diabetes). So, If you're an older adult, it is recommended to maintain a healthy diet and proper weight.   Myth:  I can stop my medicine if the blood sugar levels come back to normal Facts: No, You should not stop your diabetic medicine by yourself. Your healthcare provider will decide when to stop the medicine based on your health history. So, It is advised to speak with your doctor before deciding on your health.   Myth: Soaking feet in water helps to reduce the blood sugar level Fact: No, there is no clinical study related to soaking feet in water, which results in a drop in blood sugar levels. It is even worse and increases the risk of foot problems in diabetic individuals.   Myth: Type 2 diabetes is completely curable Fact: According to studies, type 2 diabetes cannot be cured. However, patients can return to the non-diabetes glucose range (complete remission) or prediabetes glucose level (partial remission) if proper medication or diet is followed.   Myth: Diabetic patients are restricted from eating sweets. Fact: You don't need to cut off the sweets from your diet. However, eating sweets, chocolate, or sugary food is still possible as long as it is part of a healthful diet plan. Ensure you follow our recommended dietary guidelines from your doctor or nutritionist.   Myth: Eating spicy food can reduce the risk of diabetes. Fact: No evidence proves the consumption of spicy food reduces the risk of diabetes. Speak with your doctor for a proper dietary plan during the treatment period of diabetes.   Myth: Doing exercise is not safe for diabetic patients. Fact: No, Doing regular exercise can reduce the risk of diabetes. Doing simple exercise or walking is advised to reduce the risk of diabetes.   BOTTOM LINE   Let's mark World Diabetes Day by raising awareness and helping the person with diabetes to manage it and pre-diabetic to prevent it. On this significant occasion, let's commit to dispelling myths and spreading awareness among our loved ones to shield them from the impact of this prevalent health concern. Together, let's stand against diabetes, aiming to create a world free from its grasp and ensure the well-being of our dear ones.   "Blood sugar may be sweet, but diabetes we'll defeat."
Dr Archana Gupta
Diabetes In Female
13 Nov 2023
8 mins
Breaking Stereotypes: Women's Journey with DiabetesDid you know that diabetes impacts women in distinct ways compared to men? It's a fact! Women dealing with diabetes face a greater risk of heart disease and other complications when compared to their male counterparts. Living with diabetes presents its own set of challenges, and for women, the journey can be even more intricate. From hormonal fluctuations to reproductive health, diabetes impacts women differently than men. In this blog, we will explore the distinct aspects of diabetes in females and discuss practical strategies to manage the condition effectively.   UNDERSTANDING DIABETES   You may be familiar with diabetes [https://www.mrmed.in/health-library/diabetes/common-side-effects-of-diabetes], a lifelong condition causing elevated blood glucose levels. The pancreas, responsible for producing insulin, regulates the amount of glucose in your blood. When there is an irregularity in production, this may result in diabetes. There are two distinct types: type 1 diabetes [https://www.mrmed.in/health-library/diabetes/type-15-diabetes], where the pancreas doesn't produce insulin, and type 2 diabetes [https://www.mrmed.in/health-library/diabetes/prevention-type-2-diabetes], where there's either insufficient insulin or your body's cells don't respond adequately. If you're pregnant, you might also encounter gestational diabetes (diabetes in females during pregnancy), which often resolves after giving birth.   EARLY SIGNS AND SYMPTOMS OF DIABETES   The symptoms of diabetes vary depending on blood sugar levels. Some individuals, especially those with prediabetes, gestational diabetes (diabetes in females during pregnancy), or type 2 diabetes, may not experience symptoms. In type 1 diabetes, symptoms typically manifest rapidly and with greater severity.   Common symptoms of both types of diabetes include increased thirst, frequent urination, unintentional weight loss, the presence of ketones in urine, fatigue, irritability, blurry vision, slow-healing sores, and susceptibility to infections like gum, skin, and vaginal infections.   Type 1 diabetes can onset at any age but often starts in childhood or adolescence. On the other hand, type 2 diabetes, more prevalent in those over 40, is now increasingly diagnosed in children. Noticing these symptoms is crucial for early detection and effective management of diabetes.   MAPPING DIABETES IN INDIA   According to research by the Journal of Diabetes & Metabolic Disorders, more than 1 in 10 women between the ages of 35 – 49 have diabetes [https://www.thehindu.com/sci-tech/science/prevalence-of-diabetes-among-women-high-in-southern-india/article31768117.ece] in India. A recent study examining diabetes prevalence among middle-aged women in India has revealed significant findings. Out of the 640 districts studied, 254 exhibit a notably high prevalence of diabetes, surpassing 10%, while 130 districts show a moderately high prevalence ranging from 8.7% to 10.6%. The study identified the southern and eastern regions of India as having the highest rates, contrasting with the lower prevalence observed in the central parts of the country. Factors such as obesity, hypertension, and residing in urban areas were linked to an increased risk of diabetes in females.   WOMEN'S DIABETES DEMYSTIFIED   1. Heart Health: Diabetes in females significantly enhances the risk of heart disease, making them four times more susceptible compared to men [https://pubmed.ncbi.nlm.nih.gov/22945305/]. Moreover, women tend to experience worse outcomes after a heart attack. To counter this, women must prioritize regular blood sugar monitoring, maintain a healthy diet, and engage in regular physical activity to safeguard their heart health.   2. Ethnic Disparities: Diabetes doesn't affect all females equally. African American, Hispanic/Latina, American Indian/Alaska Native, and Asian/Pacific Islander women are more likely to have diabetes than white women. Understanding and addressing these disparities is crucial for tailored diabetes management approaches that address diverse needs.   3. Infections and Diabetes: Females with diabetes face a higher risk of yeast and urinary tract infections. Elevated blood sugar levels create a favorable environment for these infections. Maintaining blood sugar within target ranges, staying hydrated, wearing breathable fabrics like cotton underwear, and emptying the bladder regularly are essential practices to prevent them.   4. Menstrual Cycle Challenges: Hormonal fluctuations in females during the menstrual cycle can affect blood sugar levels, making them unpredictable. Regular monitoring, keeping track of patterns, and potential adjustments in insulin dosage are vital to manage diabetes in females. Leading a healthy lifestyle with proper nutrition, regular exercise, and sufficient sleep can mitigate these challenges.   5. Sexual Health: Diabetes in females can impact one's interest in sex and overall sexual health. Vaginal dryness, discomfort, or pain during intercourse may arise due to nerve damage, reduced blood flow, medications, or hormonal changes. Open communication with healthcare providers is crucial to address these issues. Exploring options like using lubricants and doing tailored exercises can help.   6. Birth Control and Pregnancy: Planning for pregnancy requires meticulous management of diabetes in females. High blood sugar during pregnancy can lead to various complications, such as preeclampsia (high blood pressure during pregnancy), C-section deliveries, and increased risks for the baby. Women must collaborate with healthcare teams to optimize blood sugar levels through lifestyle changes and, if necessary, medications.   7. Gestational Diabetes: Gestational diabetes, occurring during pregnancy, requires careful management for a healthy mother and baby. Post-pregnancy, regular testing is essential, as approximately 50% of females with gestational diabetes [https://www.mrmed.in/health-library/diabetes/gestational-diabetes-mellitus] develop type 2 diabetes later on. Participation in diabetes prevention programs is encouraged to maintain a healthy lifestyle.   8. Menopause and Beyond: After menopause, hormonal changes can lead to weight gain and unpredictable blood sugar levels. Managing menopausal symptoms, adjusting diabetes medications if needed, and adopting heart-healthy choices become crucial. Regular check-ups and continued adherence to a healthy lifestyle are essential during this phase for the effective management of diabetes in females.   9. Fertility: Diabetes in females has the potential to induce infertility by delaying the onset of menarche (the first occurrence of menstruation) and exacerbating the situation through the accelerated and premature aging of the ovaries, as indicated by early menopause. Consequently, diabetes results in a reduction of a woman's reproductive lifespan.   UNDERSTANDING GESTATIONAL DIABETES: FAQS   Is it possible for me, as a diabetic woman, to get pregnant? Absolutely, it is possible for you to get pregnant. However, it is crucial to approach pregnancy planning with careful consideration of the significant risks and complications associated with uncontrolled diabetes with your healthcare provider.   What risks are associated with uncontrolled diabetes during pregnancy? Uncontrolled diabetes in females can lead to higher birth weights in babies and may necessitate delivery via C-section. The excess sugar passed through the placenta can impact the baby's health.    When should I start planning for pregnancy if I have diabetes? It is advisable to start planning 3 to 6 months in advance. This allows time for essential check-ups, adjustments to your diabetes management plan, and lifestyle modifications to ensure optimal health before conception.   How does diabetes affect fertility, and what should I be aware of? Diabetes in females can impact fertility, making it essential to assess and address any potential concerns. Regular check-ups can identify and manage factors affecting your ability to conceive.   Why is eye health important in the context of diabetes and pregnancy? Diabetes can affect eye health, and pregnancy may exacerbate these issues. Pregnancy is linked with an enhanced risk of development and progression of diabetic retinopathy (DR). Regular eye check-ups can detect complications early, ensuring that your vision and overall eye health are optimized for a healthy pregnancy.   Can dental health affect pregnancy outcomes for diabetic women? Yes, dental health is crucial for overall well-being during pregnancy in diabetic females. Poor dental health has been linked to adverse pregnancy outcomes, especially if diabetic. Regular dental check-ups and maintaining good oral hygiene practices are recommended.   Is participation in a pre-conception counseling program beneficial for diabetic women? Pre-conception counseling programs provide valuable information and support to optimize your health before pregnancy. They equip you with the knowledge and tools for a successful and healthy pregnancy journey.   TO SUM UP,   Diabetes in females encompasses a spectrum of challenges, from hormonal fluctuations to reproductive health and beyond. Women can navigate these challenges by staying informed, engaging with healthcare providers, and adopting proactive lifestyle measures. Remember, every woman's diabetes journey is unique, and a personalized approach to management is key to achieving optimal health and well-being.   "Sugar in blood, strength in heart — conquer diabetes with resilience."
Dr Archana Gupta