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Adtrinib 200mg Tablet 30's
Prescription Required
Salt Composition : Sorafenib
Manufacturer : ADLEY FORMULATIONS
Origin of Medicine : India
30 Tablet(s) In A Bottle
Introduction to Adtrinib 200mg Tablet 30's
Adtrinib Tablet belongs to the class of cancer medications known as multikinase inhibitors containing the active ingredient sorafenib. It is primarily used to treat advanced renal cell carcinoma (kidney cancer), hepatocellular carcinoma (liver cancer), and thyroid cancer.
Adtrinib Tablet is not recommended if you are allergic to the active compound and other ingredients of the medicine. Speak with your doctor immediately if you experience skin rashes, heart problems, chest pain, bleeding problems, high blood pressure, or have had or are about to have surgery. It is not recommended for use in children and adolescents. Patients with diabetes should have their blood sugar levels examined frequently to see whether the dosage of anti-diabetic medications needs to be changed to reduce the risk of low blood sugar. Your doctor will monitor liver function tests and fluid and electrolyte balance to help identify and manage potential side effects promptly.
Uses of Adtrinib 200mg Tablet 30's
- Advanced renal cell carcinoma
- Advanced hepatocellular carcinoma
- Differentiated thyroid carcinoma
Therapeutic Effects of Adtrinib 200mg Tablet 30's
Adtrinib Tablet works by inhibiting multiple protein kinases involved in tumour cell proliferation and angiogenesis (the formation of new blood vessels that supply tumours). Specifically, it targets receptors for vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and Raf kinases, which play key roles in cancer development and progression. This stops the growth and spread of the tumour cells to other organs, as well as the formation of blood vessels in the tumour cells.
Interaction of Adtrinib 200mg Tablet 30's with other drugs
Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Adtrinib Tablet and reduce effectiveness by causing undesirable side effects.
More Information about Adtrinib 200mg Tablet 30's
- Store Adtrinib Tablet Tablet in the original package at room temperature (20°C to 25°C).
- Keep it out of reach from children.
How to consume Adtrinib 200mg Tablet 30's
A healthcare professional in a hospital setting will prescribe the medicine to you. It is not recommended to take this medication with meals that are high in fat since this may reduce Adtrinib Tablet's effectiveness. If you plan to eat one, take the pills at least one hour before or two hours after.
Your healthcare professional will decide the dose based on your conditions. Avoid crushing, opening, or dissolving the tablet; swallow it whole with a glass of water. Take the Adtrinib tablet at the same time every day.
Safety Advices for Adtrinib 200mg Tablet 30's
Pregnancy
It is not recommended to take Adtrinib Tablet during pregnancy as it may harm your unborn baby. It is necessary to inform your doctor if you are pregnant or planning to become pregnant
Breast Feeding
It is unknown whether Adtrinib Tablet passes into the breast milk. It is not recommended to nurse a child during the therapy. This medication might affect your baby's growth and development. Please consult your doctor before breastfeeding.
Lungs
Consult your doctor if you have any lung diseases before starting the treatment with Adtrinib Tablet.
Liver
It is unknown whether Adtrinib Tablet is safe in individuals with liver disorders. Inform your physician if you have any liver problems before starting the treatment.
Alcohol
Alcohol consumption can lead to hepatotoxicity and might alter the metabolism of Adtrinib Tablet. Please consult your doctor for more advice.
Driving
There is no proof that Adtrinib Tablet will impair one's capacity to operate machinery or drive a car. However if you experience any of the side effects like dizziness, fatigue it is not advised to drive or operate heavy machinery.
Side Effects of Adtrinib 200mg Tablet 30's
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common:
- Nausea
- Vomiting
- Fatigue
- Diarrhoea
- Alopecia
- Hand foot skin reaction
- Gut wall bleeding
Serious:
- gastrointestinal perforation
- abnormal heart rhythm (QT prolongation)
- inflammation of the liver
- breathing or swallowing difficulties
- Stevens Johnsons Syndrome and toxic epidermal necrolysis
- Decreased blood flow to the heart
- Increased risk of bleeding (blood in urine, stool, vomit, cough, etc)
Word of Advice
Follow all instructions and dosing recommendations provided by your healthcare provider. Do not take more or less of the medication than prescribed. Report any new or worsening symptoms to your healthcare provider immediately, especially if they relate to your lungs, eyes, skin, liver, kidneys, heart, or bleeding. When undergoing this therapy, stay out of direct sunlight and wear sunscreen with an SPF of at least 50 before going outside. Adtrinib Tablet should not be stopped without first talking to your doctor. Even if you feel better or see a change in your symptoms, you should still talk to your doctor before stopping Adtrinib Tablet. It is recommended to inform your doctor about other anticancer drugs you have been taking. It's critical to maintain a sufficient fluid intake because dehydration can exacerbate symptoms such as diarrhea and other gastrointestinal disorders. Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately.
FAQs
Q 1. Can Adtrinib Tablet be taken during pregnancy or breastfeeding?
Adtrinib Tablets may harm an unborn baby and should not be used during pregnancy. It is also not recommended while breastfeeding, as it may pass into breast milk and harm the nursing infant.
Q 2. What side effects does Adtrinib Tablet typically cause?
Fatigue, weakness, diarrhoea, nausea, vomiting, lack of appetite, hand-foot skin reaction (palmar-plantar erythrodysesthesia), rash, hair thinning, elevated blood pressure, and abnormal liver enzyme levels are common adverse effects of Adtrinib Tablet.
Q 3. Will Adtrinib Tablet cause hair loss?
Alopecia, or hair thinning or loss, is a possible adverse effect of Adtrinib Tablet therapy, however it is less frequent than with certain other chemotherapy medications. While using Adtrinib Tablet, not every patient will experience hair loss, and each patient's level of hair thinning will differ.
Q 4. Can individuals with diabetes take a Adtrinib Tablet?
The decision to use Adtrinib Tablet in individuals with diabetes should be made on a case-by-case basis. Adtrinib Tablet may affect blood glucose levels, and individuals with diabetes may experience changes in glycemic control while taking the medication.
Q 5. For what duration must You take a Adtrinib Tablet?
The length of Adtrinib Tablet treatment varies based on patient-specific factors such tolerability, treatment response, and cancer kind and stage. While some individuals would only need a Adtrinib Tablet for a few months, others might need ongoing care. The length of treatment that is right for you will be decided by your healthcare practitioner based on your particular circumstance.
Q 6. What should you not take with an Adtrinib Tablet?
It is not recommended to eat foods high in fat content while on treatment with an Adtrinib Tablet. Tell your healthcare provider before taking Sorafenib if you are taking any prescription medicines, over the counter drugs, vitamins or herbal supplements.
Fact Box of Adtrinib 200mg Tablet 30's
| Molecule Name: Sorafenib | Therapeutic class: Antineoplastics
|
Pharmacological class: Multikinase inhibitors. | Indications: 1. Advanced renal cell carcinoma 2. Advanced hepatocellular carcinoma 3. Differentiated thyroid carcinoma |
| Dosage form: Tablets | Habit forming: No
|
References
1. Bayer (Pty) Ltd, [Revised on 22nd Apr 2016] [Accessed on 15th March 2024], https://www.bayer.com/sites/default/files/NEXAVAR_200_EN_PI.pdf
2. Bayer HealthCare Pharmaceuticals Inc., US Food & Drug Administration, [Revised on Dec 2018] [Accessed on 15th March 2024]], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021923s020lbl.pdf
3. Bayer AG, European Medicines Compendium (emc), [Revised on April 2023], [Accessed on 15th March 2024], https://www.medicines.org.uk/emc/files/pil.226.pdf
4. Zentiva Pharma UK Limited, Medicines Compendium (emc), [Revised on April 2022], [Accessed on 15th March 2024] https://www.medicines.org.uk/emc/files/pil.13098.pdf
5. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
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