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Andulfa 100mg Injection
Prescription Required
Salt Composition : Anidulafungin
Manufacturer : INTAS PHARMACEUTICALS LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Andulfa 100mg Injection
Andulfa 100mg injection is an antifungal medication that belongs to a class of drugs called fungal ergosterol synthesis inhibitors containing the active ingredient Anidulafungin. It is used to treat certain invasive fungal infections. It is effective against various types of invasive candidiasis, such as candidemia (Candida bloodstream infection) and esophageal candidiasis (fungal infection affecting the esophagus). Invasive candidiasis occurs when candida yeasts enter the bloodstream or other internal organs and cause systemic infections.
This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. If you develop liver problems during your treatment with this drug, your doctor may decide to monitor your liver function more closely. Andulfa 100mg injection is primarily metabolized in the liver, so it's important to assess liver function regularly, especially in patients with pre-existing liver conditions. Inform your physician, including anesthesiologists, about your treatment with this drug, especially before undergoing surgery or receiving anesthesia. The combination of certain anesthetics with this medication could interact, so it's necessary for medical professionals to be aware of your medication history.
Pay attention to any unusual symptoms like shortness of breath, breathing difficulties, lightheadedness, or dizziness during your treatment with this drug. If you experience any of these symptoms, contact your physician immediately. It is unknown whether Andulfa 100mg injection is safe for pregnant women, so it is not recommended during pregnancy due to limited data. If a woman of childbearing age is prescribed this drug, it is essential to use effective contraception during the treatment period to avoid pregnancy. The effect of this drug on breastfeeding women is not known. Breastfeeding women should contact their doctor for more advice before taking this medicine.
Uses of Andulfa 100mg Injection
- Treatment of serious fungal infections
Therapeutic Effects of Andulfa 100mg Injection
Andulfa 100mg injection works by inhibiting the beta-glucan synthesis in the cell walls of susceptible fungi. This disruption weakens the fungal cell wall, leading to the death of the fungus.
Interaction of Andulfa 100mg Injection with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Andulfa 100mg injection and reduce effectiveness by causing undesirable side effects.
More Information about Andulfa 100mg Injection
- Store Andulfa 100mg injection in the refrigerator at (2°C - 8°C).
- Do not freeze.
How to consume Andulfa 100mg Injection
Andulfa 100mg injection is administered directly into the vein intravenously (IV). It is available as a powder for reconstitution, and a physician will prepare and administer the medication through a vein. The IV infusion is usually given over a period of one to two hours.
Safety Advices for Andulfa 100mg Injection
Pregnancy
If you are pregnant, suspecting, or planning for the pregnancy, consult your doctor for more advice before taking Andulfa 100mg injection.
Breast Feeding
Andulfa 100mg injection is not recommended for use during breastfeeding as it is unknown whether the medication passes into breast milk.
Lungs
It is unknown whether Andulfa 100mg injection can be used in patients with lung diseases. Consult your doctor for more advice.
Liver
Andulfa 100mg injection should be used with caution in severe liver disease patients. A dose adjustment is required based on the condition. Inform your physician if you have any liver problems before starting the treatment.
Alcohol
It is unknown whether consuming alcohol while taking Andulfa 100mg injection is safe. Please speak with your physician.
Driving
It is unknown whether Andulfa 100mg injection alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Side Effects of Andulfa 100mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Convulsion (seizure)
- Flushing
- Rash, pruritus (itching)
- Hot flush
- Hives
- Wheezing
- Coughing
- Difficulty of breathing
Common
- Low blood potassium (hypokalaemia)
- Diarrhea
- Nausea
- Headache
- Vomiting
Word of Advice
Andulfa 100mg injection is given through intravenous infusion. Some individuals may experience infusion-related reactions, including a rash, hives, itching, or redness at the infusion site. If you notice any of these symptoms during or after the infusion, notify your physician immediately.
FAQs
Q 1. How is Andulfa 100mg injection administered?
Andulfa 100mg injection is administered intravenously (IV). The medication comes in the form of a powder that needs to be reconstituted before administration. The physician will prepare and administer the IV infusion through a vein. The infusion typically takes one to two hours.
Q 2. What are the common side effects of Andulfa 100mg injection?
Common side effects of Andulfa 100mg injection may include fever, diarrhea, nausea, vomiting, headache, and mild changes in liver function tests. You should contact your physician immediately if you experience any severe side effects.
Q 3. How often is Andulfa 100mg injection given?
The dosing frequency of Andulfa 100mg injection may vary based on the severity of the infection and the individual's response to treatment. It is usually given once daily.
Q 4. Can Andulfa 100mg injection be used in children?
Andulfa 100mg injection is approved for use in pediatric patients aged one month and older to treat invasive candidiasis. The dosing in children is based on their weight and medical condition.
Q 5. Who should avoid taking Andulfa 100mg injection?
People with known allergies to echinocandins should avoid this medication. Also, individuals with severe liver problems or a history of hypersensitivity to Andulfa 100mg injection should not take it.
Fact Box of Andulfa 100mg Injection
Molecule name: Anidulafungin | Therapeutic class: Antifungal |
Pharmacological class: Echinocandins | Indications: Treatment of severe fungal infections |
References
- Pfizer Limited, Electronic medicines compendium (EMC), [Revised on April 2022] [ Accessed on 26th July 2023], https://www.medicines.org.uk/emc/files/pil.454.pdf
- Roerig, US Food and Drug Administration, [Revised date Feb 2006], [Accessed on 26th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021632s002lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, 7th edition, Antifungal drugs, 2013, 790.
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