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  ÂAprezine 25mg Tablet
Prescription Required
Salt Composition : Hydralazine
Manufacturer : RMPL PHARMA LLP
Origin of Medicine : India
84 Tablet(s) In A Bottle
Introduction to Aprezine 25mg Tablet
Aprezine 25mg tablet contains an active component as hydralazine. It is a medication used primarily to treat high blood pressure (hypertension). It belongs to the class of drugs known as vasodilators, which work by relaxing and widening blood vessels, allowing for easier blood flow and lowering blood pressure. This reduces the workload on the heart and can help prevent complications associated with high blood pressure, such as stroke, heart attack, and kidney problems. Aprezine 25mg tablet is often prescribed when other antihypertensive medications are ineffective or cannot be used due to contraindications. It may be used alone or with other drugs to achieve adequate blood pressure control.Â
If an individual has a known allergy or hypersensitivity to Aprezine 25mg tablet or its components, its use should be avoided. Inform your healthcare provider about any pre-existing medical conditions, such as gastrointestinal disorders, liver disease, kidney disease, or other health conditions. These may require special precautions or adjustments in the use of this medication. The kidneys excrete Aprezine 25mg tablet, so individuals with renal impairment may need dosage adjustments and close monitoring. It is generally not recommended for heart failure with reduced ejection fraction, as it may not provide significant benefits in this condition.Â
Uses of Aprezine 25mg Tablet
Aprezine 25mg tablet are used to treat the following:
- Hypertension
Therapeutic Effects of Aprezine 25mg Tablet
Aprezine 25mg tablet's mechanism of action involves its direct effects on blood vessels, leading to vasodilation. When taken, it relaxes and widens the smooth muscles within the walls of arterioles (small arteries). This relaxation reduces the resistance that blood encounters as it flows through these vessels. As a result, the blood vessels dilate, allowing for increased blood flow and reducing overall systemic vascular resistance. This vasodilation leads to decreased blood pressure, which can alleviate hypertension and reduce the workload on the heart.Â
Interaction of Aprezine 25mg Tablet with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Aprezine 25mg tablet, reducing effectiveness by causing undesirable side effects.Â
More Information about Aprezine 25mg Tablet
- Store at room temperature, between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Aprezine 25mg Tablet
Aprezine 25mg tablet is used as a tablet. Swallow with a whole glass of water. Your healthcare professional will determine the specific dosage and administration guidelines based on your condition and needs.
Safety Advices for Aprezine 25mg Tablet
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Pregnancy
 ÂThe safety of Aprezine 25mg tablet during pregnancy has not been extensively studied, and limited information is available regarding its use in pregnant women. Therefore, the use of it during pregnancy should be carefully considered and evaluated by a healthcare professional, weighing the potential benefits against the potential risks.
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Breast Feeding
 ÂThe safety of Aprezine 25mg tablet during breastfeeding has not been well studied, and limited information is available regarding its excretion into breast milk. As a result, it is recommended to exercise caution when using it while breastfeeding.
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Lungs
 ÂIf you have preexisting lung conditions such as chronic obstructive pulmonary disease (COPD) or asthma, it's important to inform your healthcare provider before taking Aprezine 25mg tablet.Â
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Liver
 ÂIf you have a liver condition or a history of liver disease, it's important to inform your healthcare provider before taking Aprezine 25mg tablet. They will assess your medical history, the severity of your liver condition, and the potential benefits and risks of using the medication.
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Alcohol
 ÂMixing alcohol with medications can lead to interactions, worsen side effects, and affect overall health
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Driving
 ÂAprezine 25mg tablet is a medication that can potentially cause side effects that might affect your ability to drive safely. It's important to understand how the medication might affect you personally and to take precautions when driving if necessary.Â
Side Effects of Aprezine 25mg Tablet
Aprezine 25mg tablet causes some side effects like all medications, although not everyone will experience them.Â
Serious:
- Severe chest pain
- Rapid and significant drop in blood pressure
- Swelling of the face, lips, tongue, or throat (indicating an allergic reaction)
- Difficulty breathing or shortness of breath
- Lupus-like symptoms (joint pain, fever, skin rashes)
- Rapid or irregular heartbeat
- Numbness or tingling in the hands or feet
- Unexplained weight gain
- Blood in urine
Common:
- Headache
- Dizziness
- Lightheadedness
- Fast or irregular heartbeat (palpitations)
- Flushing (reddening of the skin)
- Nausea
- Vomiting
Word of Advice
Be cautious of its potential to lower blood pressure, leading to dizziness and fainting; rise slowly from positions to avoid sudden drops in blood pressure. Refrain from alcohol consumption while using Aprezine 25mg tablet to prevent intensifying side effects. Those with autoimmune disorders should monitor for lupus-like symptoms. Individuals with heart, liver, or kidney conditions should consult their healthcare provider for proper monitoring and potential dosage adjustments. may influence blood glucose levels in diabetes patients, requiring careful monitoring. Pregnant, breastfeeding, or planning individuals should consult their healthcare provider before use. Be mindful of potential drowsiness, dizziness, and impaired coordination, avoiding tasks requiring full alertness. Regularly assess how your body responds to it and promptly communicate any concerns to your healthcare provider.
FAQs
Q 1. What should I do if I miss a dose of Aprezine 25mg tablet?
If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and resume your regular schedule.
Q 2. Can Aprezine 25mg tablet be used in children?
Aprezine 25mg tablet is typically not used in children except in specific cases and under medical supervision. Pediatric dosages and use should be discussed with a healthcare provider.
Q 3. How long does it take for Aprezine 25mg tablet to start working?
The onset of action can vary, but you might start to notice some effects within hours to a few days of starting Aprezine 25mg tablet. However, it may take several weeks to reach its full effectiveness.
Q 4. Can Aprezine 25mg tablet interact with other medications?
Yes, Aprezine 25mg tablet can interact with other medications, including antihypertensive drugs and drugs that affect blood pressure. Inform your healthcare provider about all medications you're taking.
Q 5. Can Aprezine 25mg tablet be taken during pregnancy?
Aprezine 25mg tablet's use during pregnancy should be discussed with a healthcare provider. The potential benefits and risks to the mother and the fetus will be considered.
Q 6. What should I do if I experience side effects from the Aprezine 25mg tablet?
Contact your healthcare provider if you experience any side effects, especially severe or concerning ones. They can advise you on managing them or adjusting your treatment plan.
Q 7. Can Aprezine 25mg tablet be stopped abruptly?
It's generally not recommended to stop Aprezine 25mg tablet abruptly. Your healthcare provider will guide you on discontinuing the medication safely if needed.
Q 8. Can Aprezine 25mg tablet be used to treat heart failure?
Aprezine 25mg tablet, in combination with other medications, can sometimes be used to manage heart failure symptoms when other treatments are not effective or suitable. Your healthcare provider will determine the best treatment plan for your specific condition.
Fact Box of Aprezine 25mg Tablet
Molecule name: Hydralazine | Therapeutic class: Antihypertensive |
Pharmacological class: Direct-acting vasodilator | Indications: Hypertension |
References
- KD Tripathi, Essentials of Medical Pharmacology, Antihypertensive drugs, 7th edition, 2013, 566.
- Amdipharm UK Limited, Electronic medicines compendium (EMC), [Revised on July 2019] [ Accessed on 21st March 2022], https://www.medicines.org.uk/emc/files/pil.6707.pdf
Disclaimer
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