Axentri 150mg Tablet

Axentri 150mg Tablets are an antiretroviral drug belonging to the chemokine receptor antagonist category, containing the active ingredient Maraviroc. It is used to treat only CCR5-tropic human immunodeficiency virus type 1 (HIV-1) infection. HIV infection is mainly spread by sexual contact with anyone who has the infection or by transfer of infected blood (by sharing injection needles). This drug must be taken in combination with other medicines used to treat HIV infection.

This drug is contraindicated in individuals with severe renal impairment and may have altered drug clearance, which mainly affects the efficacy and safety of the medicine. Also, it is highly advised not to use this drug in patients with severe renal impairment. Dose adjustment is necessary for such conditions. The liver metabolizes this medicine, specifically through the cytochrome P450 enzyme. In patients with liver impairment, the clearance of Axentri 150mg Tablet may be reduced, leading to increased drug concentrations in the bloodstream. Due to the higher concentration, caution should be taken when administering the drug to individuals with liver impairment. The dosage of this drug may need to be adjusted by your doctor, or it may need to be used with extra monitoring in these individuals to ensure its safety and efficacy. During the early stages of HIV treatment, some patients may experience an inflammatory response to opportunistic infections. This condition, immune reconstitution syndrome, can occur after starting the drug or other antiretroviral therapies. Knowing this possibility and monitoring for any signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if the symptoms concern you or persist longer than usual. 

It is necessary for healthcare professionals to carefully monitor patients taking this drug for any signs or symptoms of skin or hypersensitivity reactions, such as rash, blistering, or mucosal lesions. If a severe reaction is suspected, this medicine should be immediately discontinued the drug and appropriate medical treatment initiated. Patients are also advised to report any skin or hypersensitivity reactions to their healthcare provider and to seek medical emergency immediately if they experience any symptoms of a severe reaction. Tell your doctor immediately about all the medications you have been taking recently, including herbal and supplements, before taking this Axentri 150mg Tablets.