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Azaplast 100mg Injection
Prescription Required
Salt Composition : Azacitidine
Manufacturer : RPG LIFE SCIENCES LTD
Origin of Medicine : India
1 Vial(s)
PAP Information : Contact us for latest updates.
Program Overview: RPG LIFE SCIENCES LTD, Patient Assistance Program (PAP) is dedicated to helping patients in need of Azaplast 100mg Injection. The program aims to provide eligible patients with access to the medication at a more affordable cost.
Program Benefits: Patient assistance programs (PAPs) are sponsored by pharmaceutical companies, and are an important step towards lowering overall therapy costs for patients. The purpose of these initiatives is to provide financial assistance to patients so they can obtain drugs at low or no cost. MrMed will guide you through the procedure and ensure you receive your PAP medication correctly.
Contact us for the latest updates on this exclusive offer.
Eligibility Criteria: To qualify for the Azaplast Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for Azacitidine 100mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.
Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].
Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by RPG Life Sciences can avail of it without having to purchase the medication from MrMed.
Patient Assistance Programs
Program Overview: RPG LIFE SCIENCES LTD, Patient Assistance Program (PAP) is dedicated to helping patients in need of Azaplast 100mg Injection. The program aims to provide eligible patients with access to the medication at a more affordable cost.
Program Benefits: Patient assistance programs (PAPs) are sponsored by pharmaceutical companies, and are an important step towards lowering overall therapy costs for patients. The purpose of these initiatives is to provide financial assistance to patients so they can obtain drugs at low or no cost. MrMed will guide you through the procedure and ensure you receive your PAP medication correctly.
Contact us for the latest updates on this exclusive offer.
Eligibility Criteria: To qualify for the Azaplast Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for Azacitidine 100mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.
Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].
Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by RPG Life Sciences can avail of it without having to purchase the medication from MrMed.
Introduction to Azaplast 100mg Injection
Azaplast 100mg injection is used for treating adults with Myelodysplastic syndrome (MDS) and Acute myeloid leukemia (AML) if they are considered ineligible for stem cell transplant. In Myelodysplastic Syndrome, the bone marrow does not produce healthy blood cells due to its lack of function. Acute Myeloid Leukemia is a type of bone marrow cancer caused by the release of incompletely formed blood cells into the bloodstream.
Uses of Azaplast 100mg Injection
- Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant
- Intermediate-2 and High-risk Myelodysplastic syndrome (MDS)
Therapeutic Effects of Azaplast 100mg Injection
In MDS and AML, the development of tumor cells is caused by the process of transcriptional repression of various genes, which is due to hypermethylation of DNA. Transcriptional repression is a process where proteins bind directly or indirectly to DNA and control the activity of copying a specific gene or a set of genes. The active form of Azaplast 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.
Interaction of Azaplast 100mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Azaplast 100 mg injection and cause undesirable side effects.
More Information about Azaplast 100mg Injection
Store at room temperature (15-30°C). If the product is reconstituted, it must be used immediately; if not, store it at 2-8°C for not more than 8 hours. Keep the injection out of sight and reach of children.
How to consume Azaplast 100mg Injection
Take Azaplast 100mg Injection only under the supervision of your physician. Your physician will decide the dose based on your height, weight, and general condition. Azaplast 100mg Injection shall be given under the skin of your thigh, stomach, or upper arm.
Safety Advices for Azaplast 100mg Injection
Pregnancy
Azaplast 100mg Injection could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.
Breast Feeding
Breastfeeding is not intended for patients on Azaplast 100mg Injection therapy. Consult your physician for advice.
Lungs
It is not known whether it is safe to administer Azaplast 100 mg Injection in lung failure patients. Please consult your doctor.
Liver
Inform your physician if you have been told that you have a tumor in the liver cells.
Alcohol
It is not known whether it is safe to consume alcohol with Azaplast 100mg Injection. Please consult your doctor.
Driving
It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking Azaplast 100 mg injection.
Side Effects of Azaplast 100mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Unexpected bleeding, with blood in stool and urine
- Fever
- Pneumonia, is characterized by chest pain or breathlessness.
- Allergic reaction with symptoms of swelling of lips, itching or rashes.
- Seizures, loss of consciousness, severe headache or bleeding in the brain
- Frequent urination with pain or burning sensation
Common:
- Disturbances in the blood count (RBC, WBC, Platelets)
- Nausea, vomiting, diarrhea
- Constipation
- Tiredness
- Skin reactions like redness and pain at the site of injection
- Decreased appetite
- Dizziness
- Pain in extremities
- Joint pain
- Stomach pain
- Headache
- Sore nose and throat
- Rashes and bruising
Word of Advice
Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects on the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. It is administered under the skin of your thigh, stomach, or upper arm.
FAQs
Q 1. How to use Azaplast 100mg Injection?
Take only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. Azaplast 100mg Injection is administered under the skin of your thigh, stomach or upper arm.
Q 2. Does Azaplast 100mg Injection cause hair loss?
No, Azaplast 100mg Injection does not cause hair loss even after using it for a prolonged period of time.
Q 3. How does Azaplast 100mg Injection?
Azaplast 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.
Q 4. Is Azaplast 100mg Injection chemotherapy?
Yes. Azaplast 100mg Injection is chemotherapy, and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).
Q 5. What are the side effects of Azaplast 100mg Injection?
The common side effects of Azaplast 100mg Injection are nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat, and nose.
Q 6. Is it safe to drive after taking an Azaplast 100mg Injection?
It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.
Fact Box of Azaplast 100mg Injection
Molecule name: Azacitidine | Therapeutic class: Anti-metabolites |
Pharmacological class: Anti-Neoplastics | Indications: 1. Treat advanced or metastatic non-small lung cancer (NSCLC), 2. To Treat Advanced or metastatic pancreatic cancer. |
References
- K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741, [Accessed on 5th Apr 2021] https://www.researchgate.net/publication/7094896_Transcriptional_repression_in_eukaryotes_Repressors_and_repression_mechanisms
- Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018 [Accessed on 3rd Apr 2021] https://bmchematol.biomedcentral.com/articles/10.1186/s12878-017-0094-8
- Dr.Reddy’s Laboratories, [Revised on 8th Nov 2018] [Accessed on 5th Apr 2021] https://www.drreddys.com/media/743001/ac-pm-english.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.