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Azashine 300mg Tablet
Prescription Required
Salt Composition : Azacitidine
Manufacturer : HETERO HEALTHCARE LTD
Origin of Medicine : India
14 Tablet(s) In A Strip
Introduction to Azashine 300mg Tablet
Azashine 300mg Tablet, a unique pharmaceutical agent, is specifically designed to treat severe blood disorders such as Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia, and Acute Myeloid Leukemia (AML).
It is crucial for patients who are not suitable candidates for stem cell transplantation. The active component, Azacitidine, targets the synthesis of DNA and RNA in cancer cells, significantly hindering their ability to replicate.
This intervention is vital for managing conditions that significantly impair the production and function of blood cells, potentially leading to severe health outcomes. Effective management of these conditions often increases the patient’s chances of survival and an improved quality of life. Moreover, understanding how this interacts with the body and other medications is essential for maximizing its benefits and minimizing risks.
Uses of Azashine 300mg Tablet
- Effective in managing symptoms and improving blood counts.
- Targets abnormal cell growth in the bone marrow.
- Helps in achieving remission of cancerous cells.
Therapeutic Effects of Azashine 300mg Tablet
Azashine 300 mg tablet binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells. This mechanism is critical in reducing the proliferation of malignant cells and effectively managing blood-related cancers.
Its action emphasizes its efficacy in conditions characterized by rapid cell growth, ensuring controlled disease management and extending patient survival.
Interaction of Azashine 300mg Tablet with other drugs
Prior to starting Azashine 300 mg Tablet, it is absolutely crucial to inform your doctor about all your current medications. Azashine may interact with these substances, potentially leading to undesirable effects or reduced effectiveness. This step is vital in ensuring the safe and effective use of the medication.
More Information about Azashine 300mg Tablet
Store the tablets at an ideal temperature of 25°C, away from moisture and direct sunlight. Keep out of reach of children.
How to consume Azashine 300mg Tablet
Azashine 300mg Tablet Dosages are meticulously tailored based on individual health conditions, body weight, and overall treatment objectives, ensuring that each patient feels confident in the precision and efficacy of their treatment.
To maintain its effectiveness, the tablet should be swallowed whole with water and not altered (crushed, chewed, or broken).
Safety Advices for Azashine 300mg Tablet
Pregnancy
Azashine 300 mg tablets should not be used during pregnancy. If you are pregnant or suspect you might be, please consult your doctor.
Breast Feeding
If you are breastfeeding, seek advice from your doctor before using Azashine 300 mg tablets.
Lungs
Before taking Azashine 300 mg tablets, inform your doctor if you have any respiratory issues.
Liver
If you have been diagnosed with liver cell tumors, discuss this with your physician prior to taking Azashine 300 mg tablets.
Alcohol
The safety of consuming alcohol while taking Azashine 300 mg tablets has not been established. Consult your doctor for guidance.
Driving
Operating vehicles or heavy machinery after taking Azashine 300 mg tablets is not recommended due to potential dizziness and impaired concentration.
Side Effects of Azashine 300mg Tablet
Here are some frequently seen and serious side effects you need to be aware of:
Common
- Nausea and vomiting are often experienced by many.
- Diarrhea is a frequent digestive system reaction.
- General fatigue is a widespread side effect.
- Headaches and dizziness are common neurological symptoms.
- Stomach pain and constipation are typical gastrointestinal issues.
- Rash and itching are common dermatological reactions.
Serious
- Bruising or bleeding, indicating potential blood disorders.
- Abnormal liver function test results suggest liver issues.
- Swelling of facial areas, a sign of severe allergic reactions.
- Higher risk of catching infections due to a decreased white blood cell count.
- Shortness of breath, which may indicate respiratory problems.
- Anemia, which can lead to significant fatigue and weakness.
Word of Advice
Before administering this tablet, it is crucial to notify the doctor of any allergies, respiratory issues, or existing kidney, liver, or heart conditions the patient may have, as well as any other medications being taken, since they may exacerbate the patient's health issues. This medication should not be used if the patient is trying to conceive, is pregnant, or is breastfeeding due to its potentially harmful effects on the developing baby. This tablet should be taken strictly under medical supervision, with dosages tailored by the doctor according to the patient’s height, weight, and overall health condition.
FAQs
Q 1. How successful is the Azashine 300mg Tablet?
The success of Azashine 300mg Tablet in treating certain blood cancers varies by individual and specific condition. It is effective in managing Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, and Acute Myeloid Leukemia, particularly in cases where stem cell transplantation is not possible.
Q 2. Can Azashine 300mg be given at home?
Azashine 300mg Tablet should be administered under the supervision of a healthcare professional. Home administration depends on the healthcare setup and the specific circumstances of the patient.
Q 3. Is Azashine 300mg Tablet considered a chemotherapy drug?
Yes, Azashine 300mg Tablet is used in chemotherapy. It is a cytotoxic drug that interferes with DNA synthesis in cancer cells, slowing down or stopping their growth.
Fact Box of Azashine 300mg Tablet
Molecule name: Azacitidine | Therapeutic class: Anti-metabolites |
Pharmacological class: Anti-Neoplastics | Indications: 1. Treat advanced or metastatic non-small lung cancer (NSCLC), 2. To Treat Advanced or metastatic pancreatic cancer. |
References
- K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741, [Accessed on 5th Apr 2021] https://www.researchgate.net/publication/7094896_Transcriptional_repression_in_eukaryotes_Repressors_and_repression_mechanisms
- Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018 [Accessed on 3rd Apr 2021] https://bmchematol.biomedcentral.com/articles/10.1186/s12878-017-0094-8
- Dr.Reddy’s Laboratories, [Revised on 8th Nov 2018] [Accessed on 5th Apr 2021] https://www.drreddys.com/media/743001/ac-pm-english.pdf
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