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Azel 160mg Tablet
Prescription Required
Salt Composition : Enzalutamide
Manufacturer : DR REDDY'S LABORATORIES LTD
Origin of Medicine : India
7 Tablet(s) In A Strip
Introduction to Azel 160mg Tablet
Azel 160mg tablet contains the active ingredient Enzalutamide. It is an antineoplastic drug that belongs to the category of medicines known as androgen receptor inhibitors. This medication is used in the treatment of advanced prostate cancer in patients who do not respond to surgical or hormonal treatments.
It is not recommended to take this capsules if you are allergic to any of its ingredients. During the treatment, your doctor may periodically monitor for Prostate-specific antigen (PSA) tests. This blood test measures the level of PSA, a protein produced by the prostate gland that can be elevated in men with prostate cancer. PSA levels can help monitor the progression of the disease and the response to treatment. Other tests also include liver function tests and complete blood count(CBC) to prevent serious complications.Â
This medicine can cause seizures, so patients with a history of seizures should use caution when taking this medication. Avoid grapefruit and grapefruit juice while taking this drug, as it can increase the levels of the medication in the body. This drug is not recommended during pregnancy as it causes harm to the unborn baby, and it also causes fertility issues, inform your doctor about any fertility concern you may have before starting treatment with this medicine. Before beginning this treatment, tell your healthcare provider if you are pregnant or planning to have a baby. It is advised for both men and women to follow proper contraceptive methods during and for 3 months after the last dose of Azel 160mg tablet.
Uses of Azel 160mg Tablet
- Advanced prostate cancer
Therapeutic Effects of Azel 160mg Tablet
It works by inhibiting the active form of testosterone, called dihydrotestosterone. It selectively blocks the androgen receptors and disrupts the translocation of signals from the receptor to the cell. Thus, the androgen hormone does not bind to the androgen receptors and these androgen receptors do not interact with DNA. This blocks the functioning of cancer cells and reduces its multiplication.
Interaction of Azel 160mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Azel 160mg tablet and reduce effectiveness by causing undesirable side effects.Â
More Information about Azel 160mg Tablet
- Store Azel 160mg tablet in the original package at room temperature (20°C to 25°C).
- Keep it out of reach from children and pets.
How to consume Azel 160mg Tablet
Your doctor will decide the dose and duration of Azel 160mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. The standard dose for this drug is 160 mg taken once daily, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
Safety Advices for Azel 160mg Tablet
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Pregnancy
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Azel 160mg tablet is not recommended for pregnant women as they may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
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Breast Feeding
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It is not known if Azel 160mg tablet passes into your breast milk or if it will affect your baby or your breast milk. Talk to your doctor about the best way to feed your baby if you receive this drug.
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Lungs
  It is not known whether Azel 160mg tablet can be prescribed to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
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Liver
  Inform your doctor if you have any liver disorders before taking Azel 160mg tablet. Regular monitoring of liver function tests is recommended.
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Alcohol
 ÂIt is unknown whether consuming alcohol interacts with Azel 160mg tablet. Please consult your doctor for more advice.
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Driving
  Azel 160mg tablet may cause drowsiness which can affect the patient’s ability to drive or use machines.
Side Effects of Azel 160mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Hypersensitivity
- Seizures
- Posterior reversible encephalopathy syndrome
- Heart disease
- Falls and fractures
Common
- Tiredness
- Back pain
- Constipation
- Arthralgia
- Decreased appetite
- Diarrhea
- High BP
- Headache
- Anxiety
- Dry skin
- Enlarged breasts in men
- Inability to concentrate
Word of Advice
Azel 160mg tablet causes skin dryness so it is advised to use an effective moisturiser for your skin. Ensure that you stay hydrated and maintain a balanced diet. Store the drug in the original package at room temperature (25°C). Keep it out of reach from children and pets. It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose. Avoid driving or operating heavy machines if you experience dizziness, nausea or tiredness while on treatment with this drug.
FAQs
Q 1. What tests are essential before starting treatment with Azel 160mg tablet?
Before starting treatment with Azel 160mg tablet, your healthcare provider will recommend tests for Prostate-specific antigen (PSA) tests. This blood test measures the level of PSA, a protein produced by the prostate gland that can be elevated in men with prostate cancer. PSA levels can help monitor the progression of the disease and the response to treatment. Other tests also include liver function tests and complete blood count(CBC).
Q 2. What should you do if you missed a dose of Azel 160mg tablet?
If you missed taking a dose of Azel 160mg tablet, skip this dose. Do not take two tablets to make up for the missed dose. Report to your healthcare provider right away if you missed taking more than two doses of this drug.
Q 3. Who should not take Azel 160mg tablet?
Azel 160mg tablet is not recommended for people who are allergic to this drug, and its ingredients. Also, women who are pregnant or breastfeeding should avoid taking it, because this drug can harm an unborn baby or pass into breast milk.
Q 4. Can you smoke while on treatment with Azel 160mg tablet?
It is not recommended to smoke cigarettes while on treatment with Azel 160mg tablet as smoking can reduce the concentration of this drug in the body.
Q 5. How do you know if you have overdosed on Azel 160mg tablet?
Watch out for symptoms like fatigue, tiredness, nausea, vomiting, severe headache and seek immediate medical attention from a nearby healthcare facility.
Fact Box of Azel 160mg Tablet
Molecule name: Enzalutamide | Therapeutic class: Antineoplastics |
Pharmacological class: Androgen receptor inhibitors | Indications:Â 1.Advanced prostate cancer |
References
- Astellas Pharma Ltd, [Revised on Oct 2020] [Accessed on 8th Apr 2021], https://www.astellas.us/docs/12a005-enz-wpi.pdf
- Astellas Pharma Europe B.V, Electronic Medicines Compendium (EMC), [Revised on May 2021] [Accessed on 12th Nov 2021], https://www.medicines.org.uk/emc/files/pil.10318.pdf
- MartÃn LázaroQuintela et al., Enzalutamide: a new prostate cancer targeted therapy against the androgen receptor, Cancer Treatment Reviews. Mar 2015; 41(3): 247-253 [Accessed on 8th Apr 2021],https://ruc.udc.es/dspace/bitstream/handle/2183/21551/Lzro_Enzlutamide.pdf?sequence=3&isAllowed=y
- Marina D. Kaymakcalan and Christy S. Harris, Prostate Cancer, Applied Therapeutics, The Clinical Use Of Drugs, 11th Edition, 2018, 2083-2100.
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