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Azimbra 40mg Injection
Prescription Required
Salt Composition : Adalimumab
Manufacturer : ABBOTT
Origin of Medicine : India
1 Prefilled Syringe(s)
Introduction to Azimbra 40mg Injection
Azimbra 40mg Injection is an antirheumatic agent that belongs to the class of medications called TNF (tumor necrosis factor) inhibitors. It contains the active compound Adalimumab. It is used to treat the symptoms of several autoimmune diseases either on its own or in combination with other drugs.
It is not recommended to take Adalimumab if you are allergic to active compounds or any other ingredients of this medicine. It is not advised to take Azimbra 40mg Injection if you have a severe infection like tuberculosis, sepsis and any other infections. It is not advised to take this medicine if you have a compromised immune system. If you suffer from moderate or severe heart failure, avoid using this medication. If you have an active infection, let your doctor know before beginning any treatment. Before starting any treatment, let your doctor know if you have any heart, liver, or renal issues. It is advised that children of age six or below visit your doctor before consuming Azimbra 40mg Injection. Gediatric people of age above 65 are more susceptible to infections while using Azimbra 40mg Injection, it is important to keep a track of the side effects they develop. It is advised to vaccinate your child with an up to date vaccination schedule to reduce the chance of developing infections.
The need to use Azimbra 40mg Injection during pregnancy and breastfeeding will be determined by the doctor only if absolutely necessary as it may cause infections to the child. It is recommended to use effective contraceptive methods during the therapy and 5 months after completion. Inform your doctor if you are pregnant or planning to get pregnant to know about effective contraceptive methods. It is necessary to inform your physician about all the medicines, over the counter drugs, vitamin and herbal supplements you are taking before the start of therapy. Patients taking Azimbra 40mg Injection should be closely monitored by their healthcare provider for any signs of side effects.
Uses of Azimbra 40mg Injection
- Rheumatoid arthritis
- Polyarticular juvenile idiopathic arthritis
- Enthesitis-related arthritis
- Ankylosing spondylitis
- Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis
- Psoriatic arthritis
- Plaque psoriasis
- Hidradenitis suppurativa
- Crohn’s disease
- Ulcerative colitis
- Non-infectious uveitis
Therapeutic Effects of Azimbra 40mg Injection
Azimbra 40mg Injection restricts TNF-alpha's ability to connect with its receptors, which in turn prevents TNF-alpha from mediating downstream signaling pathways. The inflammatory response, which includes immune cell activation, inflammatory cytokine generation, and recruitment of inflammatory cells to inflammatory areas, is largely regulated by these signaling pathways. By restricting the signaling pathway it decreases inflammation in various autoimmune diseases.
Interaction of Azimbra 40mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Azimbra 40mg Injection and reduce effectiveness by causing undesirable side effects. Live vaccines must not be concurrently used along with Azimbra 40mg Injection.
More Information about Azimbra 40mg Injection
- Store in a refrigerator (2°C – 8°C).
- Do not freeze.
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.
How to consume Azimbra 40mg Injection
Azimbra 40mg Injection is administered by injection under the skin (subcutaneously). The dosage and frequency of Azimbra 40mg Injection will depend on various factors, including the patient's age, weight, overall health, and the type and stage of disease being treated. It's important to follow the dosing instructions provided by a healthcare provider, and not to adjust the dosage or frequency without consulting with them first. This medicine is to be administered by injection under the skin (subcutaneously). Your doctor or other healthcare professional will train you on how to use this injection. Do not self-administer this injection until you get trained.
If a dose is missed, it should be taken as soon as possible unless it's within 6 hours of the next scheduled dose. In that case, the missed dose should be skipped and the regular dosing schedule resumed. It's important not to take a double dose of Azimbra 40mg Injection to make up for a missed dose.
Safety Advices for Azimbra 40mg Injection
Pregnancy
Azimbra 40mg Injection should not be taken while pregnant unless prescribed by a physician. Your physician will prescribe it only if necessary on an individual case to case basis. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for at least 5 months after the last dose.
Breast Feeding
The mother's clinical requirement for Azimbra 40mg Injection and any potential negative effects on the breastfed infant are compared and your physician will prescribe only if the benefits outweigh the risks. Your physician will prescribe it only if necessary on an individual case to case basis.
Lungs
Azimbra 40mg Injection should be used with caution in individuals who have respiratory issues. Let your doctor know if you have any lung conditions before starting any treatment.
Liver
Azimbra 40mg Injection should be taken cautiously in patients with liver problems. Inform your physician if you have any liver diseases before initiating the treatment.
Alcohol
Azimbra 40mg Injection is metabolized in the liver, and excessive alcohol consumption can also lead to liver damage. The use of two concomitantly may potentially increase the risk of liver problems.
Driving
Azimbra 40mg Injection may somewhat impair your ability to operate machinery, ride a bike, or drive. After taking this medication, a spinning sensation in the room and blurred vision are expected.If a patient experiences any side effects that affect their ability to drive or operate machinery safely while taking Azimbra 40mg Injection, they should avoid these activities and seek medical advice.
Side Effects of Azimbra 40mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Heart problems
- Abnormal heart beat
- Severe skin reactions
- GI bleeding
- Abnormal blood count values
- Liver injury
- Bone problems
- Infections
- Severe respiratory problems
Common:
- Injection site reactions
- Rash
- Headache
- Sinusitis
- Upper respiratory infections
- Fever
Word of Advice
If you have prescribed Azimbra 40mg Injection or any other medication, it is important to follow the instructions provided by your healthcare provider and to report any side effects or concerns promptly. Even if you feel better or see a change in your symptoms, you should still talk to your doctor before stopping Azimbra 40mg Injection. It is recommended to monitor your blood counts at regular intervals. Include anti-inflammatory foods in your diet, such as olive oil, nuts, seeds, fruits, vegetables, and fatty fish.
Include foods like avocados, almonds, seeds, and olive oil in your diet as sources of healthful fats. These fats can improve general health by lowering inflammation. To stay hydrated, sip lots of water throughout the day.
Consult your physician before getting any vaccinations because certain of them can make you sick and should not be administered while you are on this medication. If you currently have or have ever had hepatitis B, let your doctor know as this medication may make the illness more likely to recur. One may receive instruction on administering medication at home. Before administering an injection to yourself, be sure you understand all the instructions. Every time you give yourself a shot, use a new part of your body. Make sure you rotate body parts by keeping track of where you administer each shot. Injecting into areas of skin that are hard, tender, bruised, or red is not advised. Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately.
FAQs
Q 1. How long does it take for Azimbra 40mg Injection to start working?
The response to Azimbra 40mg Injection can vary among individuals and the condition being treated. Some individuals may experience improvement in symptoms within a few weeks, while others may take longer. It is important to follow the healthcare provider's instructions and allow sufficient time for the medication to take effect.
Q 2. Can Azimbra 40mg Injection increase the risk of infections?
Azimbra 40mg Injection may increase the risk of serious bacterial, viral, or fungal infections. It is essential to promptly report any signs of infection to a healthcare provider while taking this medicine. Inform your physician if you have or had any active infections.
Q 3. What are the common side effects of Azimbra 40mg Injection?
Common side effects of Azimbra 40mg Injection may include injection site reactions, such as pain, redness, or swelling. Other possible side effects include headaches, upper respiratory infections, nausea, and rash.
Q 4. How long can I take Azimbra 40mg Injection?
The duration of Azimbra 40mg Injection treatment can vary depending on the individual's condition and response to the medication. In some cases, this medicine may be used as a long-term maintenance therapy, while treatment duration may be shorter in other situations. It is important to follow the healthcare provider's guidance regarding the appropriate duration of treatment.
Q 5. Can Azimbra 40mg Injection be used in individuals with kidney or liver impairment?
Azimbra 40mg Injection may require dosage adjustments or caution in individuals with kidney or liver impairment. Healthcare providers will assess the patient's situation and determine the appropriate dosage based on renal and hepatic function.
Fact Box of Azimbra 40mg Injection
Molecule name: Adalimumab | Therapeutic class: Antirheumatic agent, Monoclonal antibody |
Pharmacological class: TNF inhibitors | Indications: 1. Rheumatoid arthritis 2. Polyarticular juvenile idiopathic arthritis 3. Enthesitis-related arthritis 4. Ankylosing spondylitis 5. Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis 6. Psoriatic arthritis 7. Plaque psoriasis 8. Hidradenitis suppurativa 9. Crohn’s disease 10. Ulcerative colitis 11. Non-infectious uveitis |
Dosage form: Injections | Habit forming: No |
References
- Amgen Limited, Electronics Medicines Compendium (emc), [ Revised on February 2023] [ Accessed on 27-03-2024], https://www.medicines.org.uk/emc/files/pil.9546.pdf
- AbbVie Inc, United States Food and Drug Administration (US FDA), [ Revised on November 2023] [Accessed on 27-03-2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/125057s423lbl.pdf
- AbbVie Inc, [Revised on February 2024], [Accessed on 27-03-2024], https://www.rxabbvie.com/pdf/humira.pdf
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