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Betatinib 100mg Capsule_203515 (1)
Betatinib 100mg Capsule_203515 (3)
Betatinib 100mg Capsule_203515 (2)
Betatinib 100mg Capsule_203515 (1)
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Betatinib 100mg Capsule

Prescription Required

Salt Composition : Acalabrutinib

Manufacturer : ADLEY FORMULATIONS

Origin of Medicine : India

MRP: 8900
Price : 7832
You Save : 1068 (12%)

30 Capsule(s) In A Bottle

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Introduction to Betatinib 100mg Capsule

Betatinib 100mg Capsule is an anticancer medicine containing the active constituent acalabrutinib. It belongs to a class of drugs called Bruton's tyrosine kinase (BTK) inhibitors. It is used to treat mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), and small lymphocytic lymphoma (SLL). MCL, CLL, and SLL are cancers of the white blood cells called lymphocytes that are part of the immune system. They differ from each other by the location where cancer occurs and the type of lymphocytes affected.

 

Before taking this medicine, inform your doctor if you have had recent surgery, bleeding problems, heart rhythm problems, infection, are pregnant, or are breastfeeding. It is not recommended for children and adolescents less than 18 years. This medicine can increase the risk of bleeding. Patients taking Betatinib 100mg Capsule should be monitored for signs of bleeding and should avoid taking other medications that can increase the risk of bleeding, such as blood thinners.


Uses of Betatinib 100mg Capsule

The Betatinib 100mg Capsule used in the treatment of:

  • Chronic lymphocytic leukemia
  • Small lymphocytic lymphoma
  • Mantle cell lymphoma

Therapeutic Effects of Betatinib 100mg Capsule

The therapeutic effect of Betatinib 100mg Capsule is to inhibit the activity of Bruton's tyrosine kinase (BTK), a protein that is essential for the survival and growth of cancer cells in certain types of lymphomas and leukemias. By blocking BTK, it can help to slow down or even stop the growth and spread of cancer cells, which can lead to a reduction in tumor size, an improvement in symptoms, and a delay in disease progression.


Interaction of Betatinib 100mg Capsule with other drugs

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Betatinib 100mg Capsule and reduce effectiveness by causing undesirable side effects. 


More Information about Betatinib 100mg Capsule

  • Store in a refrigerator between 20°C to 25°C (68°F to 77°F).
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep it in its original packaging until it is ready to be used.
  • Keep out of the reach of children and pets.

How to consume Betatinib 100mg Capsule

Betatinib 100mg Capsule is typically taken orally with or without food. The tablets should be swallowed whole and should not be crushed, chewed, or broken. The recommended dosage can vary depending on the type of cancer being treated and other factors such as your overall health and response to treatment. Do not take a double dose to make up for a missed dose.


Safety Advices for Betatinib 100mg Capsule

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Pregnancy

  

Betatinib 100mg Capsule is not safe during pregnancy. It can harm the developing fetus, so pregnancy should be avoided while taking this medicine.

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Breast Feeding

  

It is not known whether Betatinib 100mg Capsule is excreted into human breast milk, so breastfeeding women should consult a doctor before taking it.

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Lungs

  

If you have a lung disease or lung cancer and are considering treatment with Betatinib 100mg Capsule, it is important to discuss the potential benefits and risks of this medication with your healthcare provider.

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Liver

  

Betatinib 100mg Capsule can affect the liver, it elevates the liver enzymes (AST, ALT) in some patients taking it. In rare cases, severe liver injury or failure has been reported.

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Alcohol

  

Patients taking Betatinib 100mg Capsules avoid or limit their alcohol consumption, as alcohol can exacerbate certain side effects of the medication, such as fatigue and depression.

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Driving

  

Patients should always monitor their response to the Betatinib 100mg Capsule medication and be cautious when driving or operating machinery if they experience any side effects that may impair their ability to do so safely.


Side Effects of Betatinib 100mg Capsule

Like all medications, Betatinib 100mg Capsules cause some side effects, although not everyone will experience them. 


Serious:

  • Bleeding problems (bruising or bleeding)
  • Infections (pneumonia and sepsis)
  • High blood pressure
  • Heart problems (irregular heartbeat, and chest pain)
  • Kidney failure

 

Common:

  • Headache
  • Diarrhea
  • Nausea
  • Fatigue
  • Muscle and joint pain
  • Bruising or bleeding easily
  • Upper respiratory tract infection
  • Rash or itching

Word of Advice

If you have been prescribed Betatinib 100mg Capsule, it is important to carefully read and understand the warnings and precautions associated with the medication. Patients require monitoring for signs of an allergic reaction. It can cause high blood pressure. Patients should check their blood pressure regularly. Report to your doctor if you develop a lesion or change in the appearance of an area on the skin. It increases the risk of infection, so patients should avoid close contact with infected persons. Patients with diabetes require close monitoring during treatment. Pregnancy and breastfeeding should be avoided during treatment. Always maintain a healthy and balanced diet to support your overall health and well-being.


FAQs

Q 1. Can I take Betatinib 100mg Capsule if I have a history of bleeding disorders?

Patients with a history of bleeding disorders may be at an increased risk of bleeding while taking Betatinib 100mg Capsule. Before starting treatment, your healthcare provider will evaluate your bleeding risk and may recommend additional monitoring or precautions.

Q 2. Can I take Betatinib 100mg Capsule if I have a history of heart disease?

Betatinib 100mg Capsule can cause cardiac effects, including irregular heartbeat and atrial fibrillation. Patients with a history of heart disease should be closely monitored while taking it. Your healthcare provider may recommend additional monitoring or precautions.

Q 3. How this medication will affect my blood?

Betatinib 100mg Capsule can affect your blood in several ways. It may cause a decrease in the number of red blood cells, white blood cells, and platelets. This can lead to anemia, infections, and an increased risk of bleeding. Your healthcare provider will monitor your blood counts before and during treatment.

Q 4. Can I take this medication if I have diabetes?

Patients can take Betatinib 100mg Capsule with diabetes, but it is important to monitor blood sugar levels closely while taking this medication. It can cause an increase in blood sugar levels in some patients, which may require adjustments in diabetes medications or insulin dosages.

Q 5. Can I Go for Tooth extraction while taking this medication?

Patients taking Betatinib 100mg Capsule should inform their dentist and healthcare provider if they need to have a tooth extraction or any other dental procedures. This is because it can increase the risk of bleeding, and impair wound healing. Your dentist and healthcare provider may recommend temporarily stopping treatment before the dental procedure to reduce the risk of bleeding.


Fact Box of Betatinib 100mg Capsule

Molecule name: Acalabrutinib

Therapeutic class: Antineoplastic 

 

Pharmacological class: Bruton's tyrosine kinase (BTK) inhibitors

Indications: 

1. Chronic lymphocytic leukemia

2. Small lymphocytic lymphoma

3. Mantle cell lymphoma


 


References

  1. AstraZeneca, Electronica medicines compendium (EMC), [Revised on Dec 2020], [ Accessed on 5th May 2023],  https://www.medicines.org.uk/emc/files/pil.11917.pdf
  2. AstraZeneca, US Food and Drug Administration, [ Revised on Oct 2017], [ Accessed on 5th May 2023],  https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/210259s000lbl.pdf
  3. John C Byrd et al; Acalabrutinib monotherapy in patients with relapsed/refractory chronic lymphocytic leukemia: updated phase 2 results; Blood; Published on April 2020; [Accessed on5th May 2023];  https://pubmed.ncbi.nlm.nih.gov/31876911/

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