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BIOBIN 100MG INJECTION_102076_1
BIOBIN 100MG INJECTION_102076_2
BIOBIN 100MG INJECTION_102076_3
BIOBIN 100MG INJECTION_102076_4
BIOBIN 100MG INJECTION_102076_1
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Biobin 100mg Injection

Prescription Required

Salt Composition : Cytarabine

Manufacturer : ZYDUS CADILA

Origin of Medicine : India

MRP: ₹67
Price : ₹57
You Save : ₹10 (15%)

1 Vial(s)

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Introduction to Biobin 100mg Injection

Biobin 100mg injection contains the active substance Cytarabine. It is an antineoplastic drug that belongs to the class antimetabolite. It is used alone or with other chemotherapy medications to treat certain types of leukemias (a type of blood cancer with too many white blood cells), including acute myeloid leukemia (AML) and chronic myelogenous leukemia (CML). It is also indicated to use alone or with other chemotherapy drugs to treat and prevent meningeal leukemia (cancer in the membrane that covers and protects the spinal cord and brain). 

Do not take Biobin 100mg injection if you are allergic to Cytarabine or any other ingredients of this medicine. Inform your physician if you have difficulties in body coordination, or taking any other anti-cancer medications, decreased bone marrow functioning, have liver problems, or have undergone dialysis immediately before or after treatment with this medicine.  

Biobin 100mg injection may cause an increased uric acid level in your blood, your doctor will tell you if you need to take any medicine to control this. Notify your physician if you have sudden signs of allergy, such as rash, itching, or hives on the skin, swelling of the face, lips, mouth, or throat, shortness of breath, or wheezing. It is unknown whether this medicine can be administered in patients with kidney failure, inform your doctor if you have any kidney diseases. 

Uses of Biobin 100mg Injection

  • Acute myeloid leukemia (AML)
  • Chronic myelogenous leukemia (CML)
  • Meningeal leukemia

Therapeutic Effects of Biobin 100mg Injection

Biobin 100mg injection is a cytotoxic drug that acts by primarily killing cells undergoing DNA synthesis. It works by slowing or stopping the growth of cancer cells in your body. 

Interaction of Biobin 100mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, vaccines, and herbal products. Certain medications may interact with the effects of Biobin 100mg injection and reduce its effectiveness by causing undesirable side effects. Inform your physician if you are using digoxin. 

More Information about Biobin 100mg Injection

  • Store Biobin 100mg injection at room temperature (25°C)
  • Do not refrigerate or freeze.
  • Keep the injection away from the reach of children and pets.
  • If you forgot to take a dose on the scheduled day, contact your physician and reschedule the dose.
  • Do not take a double dose to make up for a forgotten dose.

How to consume Biobin 100mg Injection

Biobin 100mg injection will be given to you in a hospital setting by a trained healthcare professional. This medicine may be given by solution for injection/infusion (using a syringe) under the skin (subcutaneous) or into a vein (intravenously) or into a muscle (intramuscularly), or into the spine (intrathecal). Your doctor will decide the dose, route of administration, and duration of the treatment based on your disease condition, severity, and other factors. 

Safety Advices for Biobin 100mg Injection

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Pregnancy

  

Biobin 100mg injection is unsafe to administer in pregnant women because it may cause birth defects. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 6 months after your last dose is necessary.  

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Breast Feeding

  

Breastfeeding is not recommended in patients taking Biobin 100mg injection because the medicine passes into the breast milk in small amounts and may harm your baby. 

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Lungs

  

It is unknown whether Biobin 100mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

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Liver

  

It is unknown whether Biobin 100mg injection can be used in patients with liver disorders. Consult your doctor if you have any liver diseases before starting the treatment.

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Alcohol

  

It is not known whether it is safe to consume alcohol with Biobin 100mg injection. Please consult your doctor.

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Driving

  

Biobin 100mg injection does not affect your ability to drive or use machinery. If you are affected, consult your doctor for more advice. 

Side Effects of Biobin 100mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. 

 Common

  • Fever
  • Loss of appetite, abdominal pain
  • Swallowing difficulties
  • Nausea, vomiting
  • Diarrhoea
  • Inflammation or ulceration in the mouth or anus
  • High blood uric acid levels
  • Hair loss
  • Skin rashes
  • Speaking difficulties
  • Inflammation in the vein

Serious 

  • Swelling and irritation of the skin
  • Increased blood uric acid levels
  • Blisters of the skin
  • Irregular heartbeat
  • Lung diseases
  • Anemia
  • Infection
  • Kidney problems

Word of Advice

During the treatment with Biobin 100mg injection, the administration of vaccines is not advised. If required, consult your doctor. This medicine may cause infertility in men and women. Your doctor will do blood tests regularly to check whether the medicine works. Inform your physician if you have any ulcers or bleeding in the stomach or intestines.  This medicine may make you bleed or bruise easily; take precautions to prevent the illness.  

FAQs

Q 1. What should I monitor when taking Biobin 100mg injection?

Biobin 100mg injection may cause neurological problems, monitor for speech disturbances, eye problems, and coordination problems. Inform your physician if you have noticed any of these problems.

Q 2. What if I overdose Biobin 100mg injection?

High doses of Biobin 100mg injection can worsen side effects like sores in the mouth or may decrease the number of WBC and platelets in the blood, damages to nerves, severe lung problems, heart problems. Inform your physician if you experience any of the symptoms.

Q 3. Is Biobin 100mg injection toxic to the liver?

The safety of Biobin 100mg injection to the liver has not been well established. The drug may cause a few liver-related side effects. Inform your physician if you have liver diseases before initiating the treatment.

Q 4. Should I have to refrigerate Biobin 100mg injection?

No, do not refrigerate or freeze Biobin 100mg injection. The injection should be stored at room temperature 20°C to 25°C.

Q 5. Is Biobin 100mg injection toxic to the brain?

Intravenous administration of Biobin 100mg injection can cause peripheral neuropathy. Inform your physician if you have any symptoms of pain, numbness or weakness in the hands and feet, digestive and urination problems.

Fact Box of Biobin 100mg Injection

Molecule name: Cytarabine 

Therapeutic class: Antineoplastics 

Pharmacological class: Antimetabolite

Indications: 

1. Acute myeloid leukemia

2. Chronic myelogenous leukemia 

3. Meningeal leukemia 

References

  1. Cytarabine Injection. [cited 2020 Dec 3]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/071868s032lbl.pdf
  2. Cytarabine Injection Solution 100 mg/ml - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. [revised on 2020] [cited 2023 Mar 30]. Available from: https://www.medicines.org.uk/emc/product/1570/smpc
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1698 – 1699.
  4. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 864 - 865.

Disclaimer

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