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Bonspri Injection
Prescription Required
Salt Composition : Ofatumumab
Manufacturer : NOVARTIS INDIA LTD
Origin of Medicine : Switzerland
1 Prefilled Syringe(s)
Introduction to Bonspri Injection
Bonspri Injection contains the active ingredient Ofatumumab, belonging to the class of medicines known as monoclonal antibodies. It is indicated to treat adult patients having relapsing forms of multiple sclerosis (RMS). Inform your doctor if you have any immune system problems, cancer, or any severe infection or if you are planning on getting vaccinated before starting treatment with this medication. If you have or had hepatitis B infection, then inform your doctor before you start treatment with this medication as this medication might cause the hepatitis B virus to become active again. Â
Effective contraception is to be followed while using Bonspri Injection and is to be used for up to six months from the last dose of this medication. Inform your doctor if you get pregnant while using this medication or within six months from the last dose. Upper respiratory tract infections, decrease in the level of immunoglobulin M protein in the blood, oral herpes, pain or itching or redness or swelling at the injection site are some common side effects of this medication.Â
Uses of Bonspri Injection
Bonspri Injection is used to treat adult patients having relapsing forms of multiple sclerosis (RMS).
Therapeutic Effects of Bonspri Injection
In multiple sclerosis, the B cells (white blood cell type) which are a part of the immune system, along with the immune system attacks the protective layer surrounding the nerve cells. Bonspri Injection produces its effect by targeting and attaching to CD20 on the B cells (white blood cells) surface and causes cell lysis and depletion. This in turn reduces the chances of multiple sclerosis relapse, relieves its symptoms and slows down the disease progression.
Interaction of Bonspri Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products that you are taking or have taken before starting treatment with this medication. Certain medications may interact with Bonspri Injection and cause undesirable side effects.Â
More Information about Bonspri Injection
- Keep Bonspri Injection out of sight and reach of children.
- Keep it in the outer carton to protect from light, store in a refrigerator at 2-8 ℃ and do not freeze.
How to consume Bonspri Injection
Bonspri Injection is to be used as prescribed by your healthcare provider. Do not self administer. Â
Safety Advices for Bonspri Injection
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Pregnancy
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Bonspri Injection might be unsafe during pregnancy. If you are pregnant, think you might be pregnant or are planning to get pregnant then consult with your doctor before starting treatment with this medication. Effective contraception is to be followed while using this medication and must be used up to 6 months after the last dose. If you have used this medication while being pregnant, then consult your doctor for advice before getting your new born baby vaccinated.Â
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Breast Feeding
 ÂBonspri Injection might be unsafe during breastfeeding as this medication can pass into the breast milk. Consult your doctor regarding any breastfeeding concerns you have before starting treatment with this medication.
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Lungs
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In rare cases Bonspri injection might cause lung problems. It is advisable to inform your doctor if you have any lung diseases prior to the treatment.Â
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Liver
  Inform your doctor if you have or had hepatitis B infection before starting treatment with Bonspri Injection as this medication might cause the hepatitis B virus to become active again.
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Alcohol
 ÂCaution is advised when consuming alcohol with Bonspark Injection. Please consult your doctor.
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Driving
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It is safe to drive while using Bonspri Injection as this medication is unlikely to affect your driving ability.
Side Effects of Bonspri Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.Â
Common
- Upper respiratory tract infections (sore throat and runny nose)
- Urinary tract infections
- Decrease in the level of immunoglobulin M protein in the blood
- Oral herpes
- Pain, redness, swelling and itching at injection site.
Word of Advice
If you have used Bonspri Injection while being pregnant, then consult your doctor for advice before getting your new born baby vaccinated. If you feel your multiple sclerosis condition is worsening (like weakness or vision changes), or if you experience any new unusual symptoms while using this medication, then inform your doctor immediately. Fever, headache, muscle pain, chills and fatigue are common injection reactions that might occur while using this medication.Â
FAQs
Q 1. What is the use of Bonspri Injection?
Bonspri Injection is used to treat adult patients having relapsing forms of multiple sclerosis (RMS).
Q 2. Can Bonspri Injection cause hepatitis B infection?
Bonspri Injection might cause the hepatitis B virus to become active again. Hence, it is essential to inform your doctor if you have or had hepatitis B infection before starting treatment with this medication.
Q 3. Can I breastfeed while using Bonspri Injection?
Bonspri Injection might be unsafe during breastfeeding as this medication can pass into the breast milk. Consult your doctor regarding any breastfeeding concerns you have before starting treatment with this medication.
Q 4. Is Bonspri Injection safe for pregnant woman?
Bonspri Injection might be unsafe during pregnancy. If you are pregnant, think you might be pregnant or are planning to get pregnant then consult with your doctor before starting treatment with this medication. Effective contraception is to be followed while using this medication and must be used up to 6 months after the last dose.
Q 5. Is it safe to drive while using Bonspri Injection?
It is safe to drive while using Bonspri Injection as this medication is unlikely to affect your driving ability.
Q 6. What are the side effects of Bonspri Injection?
Upper respiratory tract infections, decrease in the level of immunoglobulin M protein in the blood, oral herpes, pain or itching or redness or swelling at the injection site are some common side effects of Bonspri Injection.
Q 7. How long should I use Bonspri Injection?
Bonspri Injection is to be used as long as prescribed by your doctor.
Fact Box of Bonspri Injection
| Molecule Name: Ofatumumab | Therapeutic Class: Antineoplastics |
| Pharmacological Class: Anti-CD20 monoclonal antibody | Indications: Relapsing forms of multiple sclerosis (RMS). |
References
- Novartis Pharmaceuticals UK Limited, Electronic Medicines Compendium (EMC), [Revised on June 2022] [Accessed on 20th August 2022], Â https://www.medicines.org.uk/emc/files/pil.12433.pdfÂ
- Novartis Pharmaceuticals Corporation, U.S. Food and Drug Administration, [ Revised on August 2020], [ Accessed on 20th August 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/125326s070lbl.pdfÂ
Disclaimer
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