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Briv 50mg Injection
Prescription Required
Salt Composition : Brivaracetam
Manufacturer : DR REDDY'S LABORATORIES LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Briv 50mg Injection
Briv 50mg Injection is an antiepileptic medication that belongs to a class of drugs known as synaptic vesicles 2 A (SV2A) protein ligands containing the active ingredient Brivaracetam. It is used to treat partial-onset seizures in patients with epilepsy. Partial-onset seizures, also known as focal seizures, are a type of epileptic seizure that begins in a specific area or focus within one hemisphere (side) of the brain. These seizures are caused by their localized onset, meaning they originate in a specific region of the brain rather than affecting the entire brain simultaneously.
This drug is contraindicated in individuals with known hypersensitivity or allergy to Briv 50mg Injection, other similar chemical compounds like levetiracetam or piracetam, or any of the other ingredients. You should not take this medication. If you have liver problems, it's important to inform your doctor before taking this medicine. Depending on the severity of your liver condition, your doctor may need to adjust your dosage or closely monitor your liver function during treatment. Children who are under 2 years of age should not take this drug.
Individuals taking anti-epileptic medicines should be aware of the possibility of experiencing thoughts of harming or killing themselves. While this is a rare side effect, being careful is essential. You should contact your physician immediately if you ever have thoughts of harming or killing yourself while taking this drug. This is important for your safety and well-being. Briv 50mg Injection is not recommended during pregnancy because its effects on pregnancy and the unborn baby are not well-known. Pregnant women should consult their doctor for alternative treatments. Breastfeeding is not advised in patients taking this drug because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Uses of Briv 50mg Injection
- Treatment of epilepsy
Therapeutic Effects of Briv 50mg Injection
Briv 50mg Injection works by selectively binding to synaptic vesicle protein 2A (SV2A) in the brain. This protein is involved in the release of neurotransmitters, including gamma-aminobutyric acid (GABA) and glutamate, which play a major role in regulating brain activity. By binding to SV2A, this drug helps stabilize the release of these neurotransmitters, reducing excessive electrical activity in the brain and preventing seizures.
Interaction of Briv 50mg Injection with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Briv 50mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Briv 50mg Injection
- Store Briv 50mg Injection at a temperature not exceeding (30°C).
- Do not freeze.
How to consume Briv 50mg Injection
Briv 50mg Injection is administered directly into the vein intravenously (IV). It is available as a powder for reconstitution, and a physician will prepare and administer the medication through a vein. The IV infusion is usually given over a period of one to two hours.
Safety Advices for Briv 50mg Injection
Pregnancy
Briv 50mg Injection is not recommended during pregnancy because its effects on pregnancy and the unborn baby are not well-known. Pregnant women should consult their doctor for alternative treatments.
Breast Feeding
Breastfeeding is not recommended in patients taking Briv 50mg Injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Lungs
It is unknown whether Briv 50mg Injection can be used in patients with lung diseases. Consult your doctor for more advice
Liver
Briv 50mg Injection should be used with caution in severe liver disease patients. A dose adjustment is required based on the condition. Inform your physician if you have any liver problems before starting the treatment.
Alcohol
It is unsafe to consume alcohol while taking Briv 50mg Injection. It may reduce the drug's effectiveness and may lead to increased side effects.
Driving
Briv 50mg Injection may cause drowsiness, dizziness, or tiredness, particularly at the beginning of treatment or after a dose increase. Therefore, individuals should avoid activities that require alertness, such as driving, cycling, or operating machinery.
Side Effects of Briv 50mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Depression
- Anxiety
Common
- Flu
- Feeling very tired (Fatigue)
- Dizziness
- Vertigo
- Feeling sick
- Constipation
- Depression
- Anxiety
- Not being able to sleep (Insomnia)
- Irritability
- Infections of the nose and throat
- Cough
- Decreased appetite
Word of Advice
Briv 50mg Injection is given through intravenous infusion. Some individuals may experience infusion-related reactions, including a rash, hives, itching, or redness at the infusion site. If you notice any of these symptoms during or after the infusion, notify your physician immediately.
FAQs
Q 1. What types of seizures does Briv 50mg Injection treat?
Briv 50mg Injection is indicated for the treatment of partial-onset seizures in patients with epilepsy. It is used as an add-on therapy for patients who have not achieved adequate seizure control with other antiepileptic medications.
Q 2. How does Briv 50mg Injection work to control seizures?
Briv 50mg Injection works by binding to a specific site on synaptic vesicle protein 2A (SV2A) in the brain. This action is thought to modulate the release of neurotransmitters, which helps to reduce excessive electrical activity and prevent seizures from occurring.
Q 3. Can Briv 50mg Injection be used alone to treat epilepsy?
Briv 50mg Injection is indicated as an adjunctive therapy, meaning it is used in combination with other antiepileptic medications to manage epilepsy and focal seizures. It is not used as a monotherapy (single-drug treatment) for epilepsy. The choice of antiepileptic regimen should be managed to the individual patient's needs and medical condition.
Q 4. What are the common side effects of Briv 50mg Injection?
Common side effects of Briv 50mg Injection may include drowsiness, dizziness, headache, nausea, and irritability. If any of these side effects bothers you, inform your physician immediately.
Q 5. What should I do if I miss a dose of Briv 50mg Injection?
If you miss a dose of Briv 50mg Injection, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Never take a double dose to make up for a missed one.
Fact Box of Briv 50mg Injection
Molecule name: Brivaracetam | Therapeutic class: Antiepileptic |
Pharmacological class: Synaptic vescicle 2 A (SV2A) protein ligands | Indications: Treatment of epilepsy |
References
- UCB Pharma Limited, Electronic Medicines Compendium (EMC), [Revised on Feb 2023] [Accessed on 1st Sep 2023], https://www.medicines.org.uk/emc/files/pil.1963.pdf
- UCB Inc, [Revised on May 2018] [Accessed on 1st Sep 2023], https://www.briviact.com/briviact-PI.pdf
- Farbod Khaleghi, Eric C. Nemec, II, Brivaracetam (Briviact) Novel Adjunctive Therapy for Partial-Onset Seizures, Pharmacy and Therapeutics, Feb 2017; 42(2): 92–96. [Accessed on 1st Sep 2023], https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5265234/
- Roger J. Porter & Michael A. Rogawski, Antiseizure Drugs, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 409-439.
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