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Calmac 50mg Tablet
Prescription Required
Salt Composition : Bicalutamide
Manufacturer : ADMAC LIFE SCIENCES
Origin of Medicine : India
10 Tablet(s) In A Strip
Introduction to Calmac 50mg Tablet
Calmac 50mg Tablet consists of the active ingredient Bicalutamide. It is used for the treatment of advanced prostate cancer. It belongs to the category of drugs called non-steroidal anti-androgens. It is prescribed along with Luteinizing Hormone-Releasing Hormone (LHRH) analog or surgical removal of testicles.Â
Calmac 50mg Tablet should be taken with or without food but should be taken at a fixed time every day. Dosage of the medication will depend on the condition of the patient. This medication should be taken as prescribed by the doctor. Do not overdose this medication as it causes serious side effects and this medicine has to be taken even when the patient is feeling well.
It is a part of androgen deprivation therapy, a combination of radiation, surgical and hormonal therapy in high-risk patients. Androgen deprivation therapy lowers the levels of testosterone considerably. Prostate cancer is sensitive to androgen and hence, this treatment aims to counteract the source and effect of androgen. Report to your physician right away if you experience side effects such as blood in urine or severe allergic reactions due to this treatment.
Uses of Calmac 50mg Tablet
- Treatment of advanced prostate cancer
Therapeutic Effects of Calmac 50mg Tablet
Calmac 50mg Tablet binds to the cytosol androgen receptors and blocks the effect of the androgen hormone. It interrupts the interaction of androgen receptors to hormones testosterone and dihydrotestosterone. This, in turn, blocks the growth of cancer cells in the prostate gland.
Interaction of Calmac 50mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Calmac 50mg Tablet and cause undesirable side effects.
More Information about Calmac 50mg Tablet
- Store at a temperature not exceeding 30ËšC. Keep out of reach of children.
How to consume Calmac 50mg Tablet
Consume the tablet at the same time each day, with or without food.
Safety Advices for Calmac 50mg Tablet
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Pregnancy
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Calmac 50mg Tablet is not indicated to be used during pregnancy.Â
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Breast Feeding
 ÂCalmac 50mg Tablet is not indicated to be used in breastfeeding women. Inform your doctor if you are breastfeeding before starting treatment with this medication.Â
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Lungs
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Talk to your doctor if you have any lung conditions before starting treatment with Calmac 50mg Tablet.
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Liver
  Calmac 50mg Tablet could cause hepatic injury. Inform your physician before starting this treatment if you have liver diseases. Your physician will monitor your liver functions regularly.
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Alcohol
 ÂIt is not known whether it is safe to use Calmac 50mg Tablet while consuming alcohol. Consult the doctor before taking this medication.
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Driving
  Avoid driving or using machinery if you experience side effects like drowsiness or dizziness while using Calmac 50mg Tablet.
Side Effects of Calmac 50mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
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- Severe allergic reactions such as rashes, swelling, wheezing, etc
- Depression
- Heart problems
- Changes in liver enzymes
- Blood in urine
Common:
- Body Pain
- Constipation
- Infection
- Nausea
- Peripheral edema
- Breathlessness
- Enlargement of breasts
- Anaemia
- Dizziness
- Weakness, swelling and breast tenderness
- Weight gain
- Indigestion
- Hair loss
- Low appetite
- Low sex drive
- Blood glucose problem
Word of Advice
This medication should be taken as prescribed by the doctor. This medication has to be taken with or without food but it should be taken at a fixed time daily. Inform the doctor about any allergic reactions, kidney, liver, diabetes, blood pressure and other medications taken for different medical conditions before starting this medication. Avoid driving and handling heavy machineries after taking this medication as it causes dizziness and individuals can lack consciousness and alertness. Blood count, blood pressure, liver, kidneys, blood glucose levels should be monitored regularly while using this medication.
FAQs
Q 1. 1. Does Calmac 50mg Tablet cause anaemia?
Yes, the common side effects of Calmac 50mg Tablet is anaemia and decreased blood count levels and monitor the blood counts while taking this medication.
Q 2. 2. Can I stop taking Calmac 50mg Tablet if I am feeling well?
Calmac 50mg Tablet should not be stopped without the proper advice of the doctor as it will worsen the condition.
Q 3. 3. Can this Calmac 50mg Tablet cause infertility?
Yes, Calmac 50mg Tablet can interfere with the fertility in men. Consult the doctor before taking this medication.
Q 4. 4. What should I avoid while taking Calmac 50mg Tablet?
Skin sensitivity is the common side effects while taking this medication. Patients are asked to avoid direct sun exposure and to use a sunscreen during treatment with Calmac 50mg Tablet.
Q 5. 5.Can Calmac 50mg Tablet cause liver damage?
Calmac 50mg Tablet could cause hepatic injury. Inform the physician before starting this treatment if the patient has liver diseases.
Fact Box of Calmac 50mg Tablet
Molecule name: Bicalutamide | Therapeutic class: Trifluoromethyl Benzene Derivative |
Pharmacological class: Antineoplastics | Indications:Â
|
References
1. AstraZeneca Pharmaceuticals, U.S. Food & Drug Administration, [Revised on Oct 2017] [Accessed on 15th June 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020498s028lbl.pdfÂ
2. AstraZeneca, Electronic Medicines Compendium (EMC), [Revised on Apr 2020] [Accessed on 6th Dec 2021], https://www.medicines.org.uk/emc/files/pil.5491.pdfÂ
3. Marina D. Kaymakcalan and Christy S. Harris, Prostate Cancer, Applied Therapeutics, The Clinical Use Of Drugs, 11th Edition, 2018, 2083-2100.
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