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Carfizome 60mg Injection
Prescription Required
Salt Composition : Carfilzomib
Manufacturer : INTAS PHARMACEUTICALS LTD
Origin of Medicine : India
1 Vial(s)
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Introduction to Carfizome 60mg Injection
Carfizome 60mg Injection is an anticancer medication containing the active constituent Carfilzomib. It is used to treat a type of cancer called multiple myeloma. Multiple myeloma is a cancer of a white blood cell called the plasma cell. These cells grow uncontrolled and accumulate in the bone marrow, damaging the bones and kidneys. The treatment with this medication reduces symptoms of multiple myelomas, such as bone pain, fatigue, and anemia, improving a patient's quality of life.
Combined with other medications, this medication can significantly increase survival rates in patients with multiple myeloma. It is often used in combination with other medications. Like all medications, it can have side effects. Common side effects include fatigue, nausea, vomiting, diarrhea, fever, and low blood cell counts. Patients need to stay hydrated while taking Carfizome 60mg Injection, as this medication causes dehydration, and dehydration can exacerbate some of the side effects of the medication. It effectively treats multiple myeloma, and the benefits may outweigh the risks for many patients.
Uses of Carfizome 60mg Injection
Carfizome 60mg Injection is used to treat-
- Multiple myeloma
Therapeutic Effects of Carfizome 60mg Injection
Carfizome 60mg Injection is a proteasome inhibitor, which means it works by blocking the action of proteasomes, the enzymes responsible for breaking down proteins in cells. By blocking proteasomes, this medication can prevent the growth and survival of cancer cells, ultimately leading to the death of cancer cells. This can help to slow or stop the progression of multiple myeloma and may improve survival rates for some patients.
Interaction of Carfizome 60mg Injection with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Carfizome 60mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Carfizome 60mg Injection
- Carfizome 60mg Injection should be stored under refrigeration between 2°C to 8°C (36°F to 46°F).
- Keep in the original package until it is ready to use.
- Should not be frozen.
- Discard any unused portion after 4 hours.
- Keep reaching out of children and pets.
How to consume Carfizome 60mg Injection
Carfizome 60mg Injection is typically administered as an intravenous (IV) injection in a hospital or clinical setting by a healthcare provider. The exact dosing and frequency of administration will depend on the specific condition being treated and other individual factors, such as the patient's age, weight, and overall health. If a dose is missed, your healthcare provider as soon as possible to determine the appropriate course of action. Suppose the missed dose is discovered within a few hours of the scheduled time. In that case, your healthcare provider may recommend administering the missed dose as soon as possible. However, if more than a few hours have passed since the missed dose, your healthcare provider may recommend skipping the missed dose and resuming the regular dosing schedule at the next scheduled time. Should not double up on doses to make up for a missed one.
Safety Advices for Carfizome 60mg Injection
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Pregnancy
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Carfizome 60mg Injection is unsafe for pregnant women as it may cause fetal harm. So it is not recommended to take it during pregnancy.
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Breast Feeding
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It is unknown whether Carfizome 60mg Injection is excreted in human breast milk. So breastfeeding mothers should consult a doctor before taking it.
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Lungs
  Carfizome 60mg Injection can cause lung-related side effects, such as shortness of breath, coughing, and pulmonary hypertension. Patients with pre-existing lung conditions, such as chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD), may be at increased risk of these side effects.
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Liver
  There is limited information on the use of Carfizome 60mg Injection in patients with severe liver impairment, and caution is advised in this population. If you have a liver impairment or a history of liver disease, it is better to consult your healthcare provider before starting treatment.
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Alcohol
 ÂThere is limited information on the interaction between alcohol and Carfizome 60mg Injection. However, it is generally recommended to avoid or limit alcohol consumption during treatment.
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Driving
  Carfizome 60mg Injection may cause side effects such as fatigue, dizziness, or blurred vision that can impair a patient's ability to drive or operate machinery safely. So you should avoid these activities during treatment with this medication.
Side Effects of Carfizome 60mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Cardiac events such as heart failure, heart attack, or arrhythmias
- Blood clotting disorders or bleeding
- Acute kidney injury
- Lung damage or inflammation
- Infections
- Tumor lysis syndrome (a condition that can occur when cancer cells break down rapidly)
Common side:
- Fatigue
- Nausea and vomiting
- Diarrhea
- Low blood cell counts (anemia, white blood cell count, platelet count)
- Fever
- Headache
- Difficulty breathing or shortness of breath
- Cough
- Muscle weakness or pain
- Rash
- Back pain
Word of Advice
It is important to take the Carfizome 60mg Injection as directed by a healthcare professional. Patients should also inform their doctor of any pre-existing medical conditions and any other medications they may be taking. It is important to be aware of the potential side effects and to report any concerns to your healthcare provider. Pregnant or breastfeeding women should consult their doctor before taking it, as the drug may pose a risk to the baby. There are no specific dietary restrictions for patients taking this medication. However, it is generally recommended that patients with cancer maintain a healthy and balanced diet to support their overall health and well-being. Drinking plenty of water and other fluids, such as clear broths or herbal teas, can help to prevent dehydration.
FAQs
Q 1. Can Carfizome 60mg Injection be used in combination with other cancer treatments?
Yes, Carfizome 60mg Injection is often combined with other cancer treatments, such as chemotherapy or immunotherapy. Your healthcare provider will determine the most appropriate treatment plan based on the specifics of your cancer diagnosis and individual health status.
Q 2. Can Carfizome 60mg Injection cure multiple myeloma?
While Carfizome 60mg Injection is an effective treatment for multiple myeloma, it is not considered a cure. However, it can help to slow the progression of cancer and improve the quality of life for many patients.
Q 3. Can I take over-the-counter medications while on Carfizome 60mg Injection?
It is important to consult with your healthcare provider before taking any over-the-counter medications while on Carfizome 60mg Injection, as some may interact with the treatment and affect its effectiveness.
Q 4. Will I lose my hair during treatment with Carfizome 60mg Injection?
Hair loss is not a common side effect of Carfizome 60mg injection treatment. However, other side effects, such as fatigue and nausea, may affect your quality of life during treatment.
Q 5. Can I take Carfizome 60mg Injection if I have tuberculosis?
Carfizome 60mg Injection is generally not recommended for use in patients with an active infection, including tuberculosis. This is because this medication can suppress the immune system, which may increase the risk of infection or interfere with the body's ability to fight off an existing infection.
Fact Box of Carfizome 60mg Injection
Molecule name: Carfilzomib | Therapeutic class: Anticancer |
Pharmacological class: Protease Inhibitor | Indications:Â 1. Multiple myeloma |
References
- Amgen Limited, Electronic medicines compendium (EMC), [Revised on August 2021] [ Accessed on 13th April 2023], https://www.medicines.org.uk/emc/files/pil.5061.pdf
- Onyx Pharmaceuticals, Inc, US Food and Drug Administration, [Revised on Feb 2019] [ Accessed on 13th April 2023],Â
- Anderson KC, Munshi NC. Hematologic Malignancies: Multiple Myeloma and Related Plasma Cell Disorders. New York: Springer; 2019.
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/202714s025lbl.pdf
- Kimberly Redic; Carfizome 60mg Injection: A novel agent for multiple myeloma; The Journal of Pharmacy and Pharmacology, [ Revised on Aug 2013], [Accessed on 13th April 2023] https://pubmed.ncbi.nlm.nih.gov/23837578/
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