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Carginil 48mg Injection
Prescription Required
Salt Composition : Nicorandil
Manufacturer : CELON LABORATORIES LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Carginil 48mg Injection
Carginil 48mg Injection is an anti-anginal medication containing the active ingredient Nicorandil. It is a medication that combines nitrate and potassium channel activator properties. It treats unstable angina, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart muscle.
This drug should not be taken by individuals with a known hypersensitivity or allergy to the medication or its components. Individuals with kidney or liver problems may require special monitoring while taking this drug. Adjustments to the dosage may be necessary based on your kidney and liver function. Patients with symptoms of dehydration should not take Carginil 48mg Injection. This medicine can affect electrolyte levels, particularly potassium. Individuals with imbalances in potassium or other electrolytes should be monitored closely while taking this medication.
This drug may cause gastrointestinal ulcers. Inform your doctor if you have a history of ulcers or if you experience symptoms such as abdominal pain or discomfort. There is no safety data on this drug during pregnancy and breastfeeding. Hence it is not recommended to administer Carginil 48mg Injection. Consult your doctor before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.
Uses of Carginil 48mg Injection
- Treatment of unstable angina (heart-related chest pain).
Therapeutic Effects of Carginil 48mg Injection
Carginil 48mg Injection works by dilating (widening) blood vessels, which increases blood flow to the heart muscle and reduces the workload on the heart. It also has the additional effect of opening potassium channels in smooth muscle cells, leading to further relaxation of blood vessels.
Interaction of Carginil 48mg Injection with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Carginil 48mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Carginil 48mg Injection
- Store Carginil 48mg Injection in a refrigerator.
- Do not freeze.
How to consume Carginil 48mg Injection
Carginil 48mg Injection can be administered only as an intravenous injection into a vein by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.Â
Safety Advices for Carginil 48mg Injection
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Pregnancy
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Safety data for this Carginil 48mg Injection during pregnancy is unknown. Therefore, it is not recommended to administer this drug during pregnancy.
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Breast Feeding
 ÂIt is not known if Carginil 48mg Injection passes into your breast milk or if it will affect your baby. Hence, breastfeeding should be avoided.
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Lungs
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It is unknown whether Carginil 48mg Injection is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.Â
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Liver
  It is unknown whether Carginil 48mg Injection is safe for patients with liver problems. Inform your physician if you have liver disease before starting the treatment.Â
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Alcohol
 ÂIt is unsafe to drink alcohol while taking Carginil 48mg Injection. It may reduce the drug's effectiveness and can cause toxic side effects
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Driving
  It is unknown whether the Carginil 48mg Injection alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.Â
Side Effects of Carginil 48mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Decrease in blood pressure
- Increase in heart rate
- Changes in liver functions
Common
- Headache
- Light headedness
- Numbness
- Nausea, vomiting, stomach discomfort
- Anaemia
Word of Advice
Carginil 48mg Injection can cause a drop in blood pressure, leading to dizziness, lightheadedness, or fainting, especially when standing up. Use caution when getting up from a sitting or lying position.
FAQs
Q 1. Can Carginil 48mg Injection be used for other conditions besides angina?
Carginil 48mg Injection is primarily indicated for angina. It's not recommended to use this drug for other conditions without consulting a doctor.
Q 2. Who should not take Carginil 48mg Injection?
Carginil 48mg Injection is contraindicated in individuals who have severe low blood pressure, have had a recent heart attack, have severe anemia, have certain heart conditions, or have experienced serious side effects from nitrate medications.
Q 3. Can Carginil 48mg Injection be used during pregnancy and breastfeeding?
The safety of Carginil 48mg Injection during pregnancy and breastfeeding is not well-established. Consult your doctor before using this drug in these situations.
Q 4. Are there any common side effects of Carginil 48mg Injection?
Common side effects of Carginil 48mg Injection may include headaches, dizziness, flushing, and nausea. These side effects are usually temporary and tend to improve with time.
Q 5. Can Carginil 48mg Injection interact with other medications?
Carginil 48mg Injection can interact with certain medications, including nitrates, certain blood pressure medications, and phosphodiesterase inhibitors (e.g., sildenafil). Inform your doctor about all medications you are taking to avoid such interactions.
Fact Box of Carginil 48mg Injection
Molecule name: Nicorandil | Therapeutic class:Â Anti-anginal |
Pharmacological class: Vasodilators | Indications: Treatment of Unstable angina (heart-related chest pain) |
References
- Torrent Pharmaceuticals Ltd., [Revised on May 2014] [Accessed on 19th August 2023], https://www.torrentian.com/pisheet/Upload/PI_Sheet/174.pdf
- Bertram G. Katzung, Vasodilators & the Treatment of Angina Pectoris, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 194-211.
- Thomas Eschenhagen, Treatment of Ischemic Heart Disease, Goodman & Gliman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 489-506.
Disclaimer
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