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Ciszest 50mg Injection
Prescription Required
Salt Composition : Cisplatin
Manufacturer : ZEE LABORATORIES LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Ciszest 50mg Injection
Ciszest 50mg injection belongs to the medication class known as an alkylating agent. It is an antineoplastics medicine that contains the active ingredient Cisplatin. It treats a certain type of cancer, such as testicular, ovarian, bladder, lung, cervical, head, and neck epithelial tumor, as a single or combined with radiotherapy. If you are allergic to this drug or its ingredients, tell your doctor before starting treatment with this medication. Notice your doctor if you have hypersensitivity, myelosuppression (lower number of blood cells), or hearing difficulties. This medicine should not be taken if you have recently been vaccinated with a live vaccine, including yellow fever. So, inform your doctor if you are planning to have one.Â
Inform your doctor if you have any symptoms of nerve damage (peripheral neuropathy) and if you have had any radiotherapy to the head. This medicine may cause problems with your kidney, liver, and blood. So, your doctor may perform blood tests regularly to monitor your blood, kidney, and liver function. Both men and women are recommended to use effective contraception while receiving this medication and continue to use it for six months, even after receiving the final dose. This medicine may reduce fertility permanently in men. So it is advised to get suggestions about fertility concerns from your doctor.
Uses of Ciszest 50mg Injection
Ciszest 50mg injection has been indicated for treating:
- Testicular tumor
- Ovarian tumor
- Bladder tumor
- Lung cancer
- Head and neck epithelial tumor
- Cervical cancer
Therapeutic Effects of Ciszest 50mg Injection
It works by stopping the growth and division of cancer cells. It does this by binding to the DNA in the cancer cells and preventing them from replicating.
Interaction of Ciszest 50mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional and vitamin supplements, vaccines, and herbal products. Certain medications include antibiotics, Bleomycin, Methotrexate, paclitaxel, antihistamines, ifosfamide, and water tablets (loop diuretics, antibiotics called aminoglycosides) may interact with the effects of Ciszest 50mg injection and reduce its effectiveness by causing undesirable side effects.
More Information about Ciszest 50mg Injection
- Store at a temperature below 25ËšC. Do not refrigerate.
- Keep the vials away from direct sunlight.
- Keep this medicine out of sight and reach of children.
How to consume Ciszest 50mg Injection
Ciszest 50mg injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Safety Advices for Ciszest 50mg Injection
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Pregnancy
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Ciszest 50mg injection is unsafe to use during pregnancy as it may cause harmful effects on the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment.Â
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Breast Feeding
 ÂBreastfeeding during this treatment may not be safe. Your physician might suggest you to stop breastfeeding for some time, depending on your condition.
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Lungs
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Consult your doctor if you experience symptoms like difficulties in breathing or chest pain while taking Ciszest 50mg injection.
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Liver
  Inform your physician before starting this treatment if you have liver disease. Your physician will monitor your liver functions regularly.
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Alcohol
 ÂIt is unknown whether consuming alcohol while taking a Ciszest 50mg injection is safe. Please speak with your physician.
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Driving
  Ciszest 50mg injection could cause sleepiness, vomiting, etc. Avoid driving or using machinery if you experience these side effects.
Side Effects of Ciszest 50mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Allergic reactions
- Neuropathy
- Kidney problems
- Severe chest pain
- Pain or swelling at the site of injection
- Confusion, slurry speech, paralysis
- Stroke
Common
- Blood clots in vein
- Fast, irregular or slow heartbeats
- Sepsis
- Decrease in bone marrow function
- Decrease in the number of WBC, RBC, Platelets (thrombocytopenia) sodium in blood
- High temperature
- Vomiting
Word of Advice
If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Notify your doctor immediately if you have undergone any radiotherapy in your head. Inform your doctor immediately if you took any live vaccines inducing yellow fever and other medications before starting with Ciszest 50mg injection because it might reduce the effectiveness of this medicine and may cause side effects. Discuss your fertility problem with the doctor since, in men, this medicine can cause permanent infertility. So it is advised to get suggestions about fertility concerns. Avoid planning for the pregnancy. Inform your physician if you have pre-existing hearing conditions, blood disorders, neuropathy, or dehydration. You are recommended to drink a lot of water for 24 hours after receiving this drug to prevent or lessen kidney issues.
FAQs
Q 1. How does Ciszest 50mg injection work?
Ciszest 50mg injection works by stopping the growth and division of cancer cells. It does this by binding to the DNA in the cancer cells and preventing them from replicating.
Q 2. How long does Ciszest 50mg injection treatment last?
The length of Ciszest 50mg injection treatment can vary depending on the type and stage of the cancer being treated and the individual's response to the treatment. Treatment may last several weeks or months and may be given in cycles.
Q 3. Can Ciszest 50mg injection be used in combination with other treatments?
Yes, it is often used with other chemotherapy drugs or radiation therapy to improve its effectiveness.
Q 4. How is Ciszest 50mg injection dosage determined?
Ciszest 50mg injection dosage is based on several factors, including the type and stage of the cancer being treated, the individual's overall health, and their response to the treatment.
Q 5. Why do I feel numbness and tingling while taking Ciszest 50mg injection?
Numbness and tingling in the hands and feet are common side effects of Ciszest 50mg injection. This is known as peripheral neuropathy and is caused by damage to the nerves that control feeling and movement in the hands and feet. This medicine can damage these nerves, leading to numbness, tingling, or a burning sensation in the hands and feet. If you are experiencing this while taking this treatment, it is important to inform your doctor. They may adjust your dosage or recommend other treatments to help manage your symptoms.
Q 6. What should I inform the doctor about before starting treatment with Ciszest 50mg injection?
Before starting treatment with Ciszest 50mg injection, it is important to inform your healthcare provider of any medical conditions you have, such as kidney disease, hearing loss, or nerve damage, as well as any medications, supplements, or herbal remedies you are currently taking. Your healthcare provider may need to adjust your dosage or monitor you more closely during treatment to prevent complications.
Fact Box of Ciszest 50mg Injection
Molecule name: Cisplatin | Therapeutic class: Antineoplastics |
Pharmacological class: Alkylating agent | Indication:Â 1.Testicular tumor 2.Ovarian tumor 3.Bladder tumor 4.Lung cancer 5.Head and neck epithelial tumor 6.Cervical cancer |
References
- Accord Healthcare Ireland Ltd, [Revised on Feb 2019] Accessed on 31st March 2023], https://www.accord-healthcare.com/ie/sites/default/files/spc/spc_cisplatin_1_mg.ml_concentrate_for_solution_for_infusion_pa_2315.081.001.pdf
- Hospira UK Limited, Electronic Medicines Compendium (EMC), [Revised on Dec 2022] [Accessed on 31st March 2023], https://www.medicines.org.uk/emc/files/pil.3788.pdf
- Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
Disclaimer
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