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  ÂCloral Lozenges
Prescription Required
Salt Composition : Clotrimazole
Manufacturer : AUREATE HEALTHCARE PVT LTD
Origin of Medicine : India
10 Lozenges(s) In A Strip
Introduction to Cloral Lozenges
Cloral Lozenges contains an active component such as Clotrimazole. This medication is an antifungal medication used to treat a variety of fungal infections. It belongs to the imidazole class of antifungals and works by inhibiting the growth and reproduction of certain types of fungi. It is highly effective in treating various fungal infections, including vaginal yeast infections, athlete's foot, ringworm, and jock itch. It targets the underlying cause of the infection and helps to alleviate symptoms such as itching, redness, and inflammation. This medication is generally well-tolerated by most people when used as directed. Serious side effects are rare, and it is considered safe for adults and children when used appropriately. In some cases, Cloral Lozenges can be used preventively to reduce the risk of recurring fungal infections, especially in susceptible individuals or those with frequent infections. Cloral Lozenges can be combined with other medications to enhance the effectiveness of treatment for certain fungal infections.
This medication may not be suitable for individuals with certain underlying medical conditions or those taking specific medications. Always inform your healthcare provider about your medical history and current medications before using Cloral Lozenges. You should avoid using it if you have a known allergy to Cloral Lozenges or any other antifungal medication within the imidazole class. Care should be taken to avoid getting it in the eyes, as it may irritate the eye. This medication should not be used in the ear canal to treat otitis externa (inflammation of the outer ear) if the eardrum is perforated or has a tube in place. It is not suitable for treating eye infections or for use in the eyes. If you have an eye infection, consult an eye care professional for appropriate treatment.
Uses of Cloral Lozenges
Cloral Lozenges are used to treat the following:
- Fungal infections like candidiasis.
Therapeutic Effects of Cloral Lozenges
Cloral Lozenges's mechanism of action is based on its ability to inhibit the synthesis of ergosterol, a vital component of fungal cell membranes. Ergosterol maintains the integrity and fluidity of the fungal cell membrane. This medication targets an enzyme called 14-alpha demethylase, essential for converting lanosterol to ergosterol in the fungal cells. By inhibiting this enzyme, this medication disrupts the synthesis of ergosterol, accumulating toxic sterol intermediates and causing structural damage to the fungal cell membrane.Â
As a result, the cell becomes more permeable, allowing essential cellular components to leak out and leading to the death of the fungal organism. Since human cells do not produce ergosterol and have different enzymes for cholesterol synthesis, it exhibits selective toxicity, effectively targeting fungal pathogens while sparing human cells.
Interaction of Cloral Lozenges with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Cloral Lozenges, reducing effectiveness by causing undesirable side effects.Â
More Information about Cloral Lozenges
- Store at room temperature, between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Cloral Lozenges
To use Cloral Lozenges, place one in your mouth and allow it to dissolve slowly without chewing or swallowing. Avoid eating or drinking for some time after dissolution. Follow the prescribed dosage and treatment duration, and consult your healthcare provider.
Safety Advices for Cloral Lozenges
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Pregnancy
 ÂIt is essential to consult with your healthcare provider before using Cloral Lozenges. They can assess your health status, consider any potential risks or benefits, and provide personalized recommendations based on your specific situation.
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Breast Feeding
 ÂCloral Lozenges are generally considered safe to use while breastfeeding when used as directed. But, it is recommended to exercise caution and consult a doctor before using it while breastfeeding.
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Lungs
 ÂIf you are experiencing lung-related symptoms or respiratory infections, it's essential to consult a healthcare professional for proper evaluation, diagnosis, and appropriate treatment options.Â
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Liver
 ÂIf you have liver disease or are concerned about using Cloral Lozenges due to your liver health, it's essential to consult your healthcare provider.Â
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Alcohol
 ÂIf you have a fungal infection in the mouth or throat and you consume alcohol regularly, it's advisable to moderate your alcohol intake and seek medical attention for proper diagnosis and treatment.
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Driving
 ÂClotrimazole is not known to cause drowsiness or impair cognitive or motor functions that could impact driving performance. Therefore, using Cloral Lozenges is unlikely to interfere with your ability to drive safely.
Side Effects of Cloral Lozenges
Cloral Lozenges cause some side effects like all medications, although not everyone will experience them.Â
Serious:
- Severe allergic reactions
- Mouth or throat pain, redness, or ulcers
Common:
- Abnormal liver functions
- Nausea, vomiting, unpleasant mouth sensations
- Pruritus
- Local irritation
- Stinging or burning sensation
Word of Advice
When using Cloral Lozenges, it is essential to follow certain instructions for safe and effective use. Firstly, inform your healthcare provider about any allergies to clotrimazole or similar antifungal medications. If pregnant or breastfeeding, seek medical advice before using the lozenges. These are intended for oral use only and should not be applied to the eyes or ears. Avoid chewing or swallowing the lozenge whole; let it dissolve slowly in the mouth. For individuals with liver or kidney impairment or compromised immune systems, consult a healthcare provider for proper dosage and suitability. To prevent recurrence, complete the full course of treatment as prescribed, even if symptoms improve. If new or worsening mouth or throat pain, redness, or ulcers occur, discontinue use and consult a healthcare provider. Follow any additional warnings and instructions on the product's packaging. Regular dental check-ups and good oral hygiene practices are advisable during use. Store the lozenges properly in a cool, dry place, and do not use them past their expiration date. If any concerns or side effects arise, seek medical advice promptly.
FAQs
Q 1. How often should I take Cloral Lozenges?
The dosing frequency of Cloral Lozenges can vary depending on the severity of the infection and the specific instructions provided by your healthcare provider. Typically, lozenges are used several times a day for a specific period. Always follow your healthcare provider's recommended dosage and treatment duration.
Q 2. Can I chew or swallow the clotrimazole lozenge?
No, Cloral Lozenges are not meant to be chewed or swallowed whole. They should be allowed to dissolve slowly in the mouth without chewing. Chewing or swallowing the lozenge whole may reduce its effectiveness.
Q 3. Can Cloral Lozenges be used for children?
Cloral Lozenges may be suitable for older children and adolescents. However, following the product's labeling and consulting a healthcare provider for appropriate use in younger children or infants is essential.
Q 4. Can Cloral Lozenges be used for vaginal yeast infections?
No, Cloral Lozenges is not intended for treating vaginal yeast infections. They are specifically formulated for oral use to treat fungal infections in the mouth and throat.
Q 5. Are there any side effects of Cloral Lozenges?
Cloral Lozenges may cause mild side effects like mouth or throat irritation. Serious side effects are rare, but allergic reactions and severe mouth or throat pain may occur. Consult your healthcare provider promptly if you experience any unexpected or concerning side effects.
Fact Box of Cloral Lozenges
Molecule name: Clotrimazole | Therapeutic class: Antifungal |
Pharmacological class: Imidazole | Indications: Fungal infection |
References
- Paddock Laboratories LLC, [Revised on Nov 2018] [Accessed on 31st July 2023], https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=3f57ef51-8202-4d0b-95a8-d2df468b8d9a&type=pdf
- KD Tripathi, Antifungal Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 838-848.
- G. Maartens, HIV Infection & AIDS, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 387-410.
- Harry W. Lampiris, Daniel S. Maddix, Antifungal Agents, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 853-862.
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