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Curosurf 120mg Injection
Prescription Required
Salt Composition : Poractant Alfa
Manufacturer : PAVIOUR PHARMACEUTICALS PVT LTD
Origin of Medicine : India
1 Vial(s) Of 1.5ml
Introduction to Curosurf 120mg Injection
Curosurf 120mg injection contains active components such as Poractant alfa. It is a lung surfactant medication used to treat Respiratory Distress Syndrome (RDS) in premature infants. It is a lifesaving medication that has improved the survival and outcomes of many premature infants. It has been shown to reduce the risk of death, the need for mechanical ventilation, and the length of hospital stay in premature infants with RDS. It is a good option for infants who are at risk for developing bronchopulmonary dysplasia (BPD), a chronic lung disease that can develop in premature infants. It is more stable than other surfactant medications, which means it can be stored longer without losing effectiveness.
If someone is hypersensitive to Curosurf 120mg injection, they should not receive the medication. They may experience a severe allergic reaction, such as anaphylaxis. It should not be used for infants with severe RDS. This is because the medication may not be effective in these infants. This medication should not be given to infants with a history of porcine protein hypersensitivity. This medication can increase the risk of bleeding. Therefore, it should not be given to infants with active bleeding. It may not be effective in infants with neonatal pneumonia and meconium aspiration syndrome. Curosurf 120mg injection is not used in old age because it is ineffective in adults.
Uses of Curosurf 120mg Injection
Curosurf 120mg injection is used in the following:
- Respiratory distress syndrome (RDS)
Therapeutic Effects of Curosurf 120mg Injection
Curosurf 120mg injection lowers the surface tension in the lungs by forming a film on the surface of the alveoli, the tiny air sacs in the lungs. This film reduces the force of attraction between the water molecules in the alveoli, making it easier for them to stay open.
Interaction of Curosurf 120mg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Curosurf 120mg injection, reducing effectiveness by causing undesirable side effects.Â
More Information about Curosurf 120mg Injection
- Should be stored at room temperature, between 2°C to 8°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Curosurf 120mg Injection
Curosurf 120mg injection is administered through a breathing tube into the infant's lungs. This is called endotracheopulmonary administration. It is a relatively simple procedure that can be done in a hospital setting.
Safety Advices for Curosurf 120mg Injection
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Pregnancy
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If it is always better to consult a doctor before using Curosurf 120mg injection if you are pregnant or planning to become pregnant.
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Breast Feeding
 ÂCurosurf 120mg injection's safety during breastfeeding is not well established. Consult a healthcare provider before using this medication while breastfeeding.Â
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Lungs
  If you have lung conditions, it is advisable to consult your healthcare provider before Curosurf 120mg injection
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Liver
  Individuals with liver disease should consult a doctor regarding the use of Curosurf 120mg injection.Â
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Alcohol
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It is unsafe to take Curosurf 120mg injection with alcohol as it can increase the risk of bleeding and other complications.
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Driving
  Driving is unsafe after receiving Curosurf 120mg injection as it can cause drowsiness and dizziness.
Side Effects of Curosurf 120mg Injection
Curosurf 120mg injection causes some side effects like all medications, although not everyone will experience them.Â
Serious:
- Anaphylaxis
- Bleeding
- Pulmonary hemorrhage
- Intracranial hemorrhage
- Surfactant protein B deficiency
Common
- Bradycardia
- Hypotension
- Hypoxemia (decreased oxygen)
- Respiratory distress
- Apnea
- Froth at the mouth
- Irritation at the injection site
Word of Advice
When receiving Curosurf 120mg injection, it is important to tell your doctor about all of your medical conditions and medications. Be aware of the signs and symptoms of an allergic reaction, such as hives, swelling, difficulty breathing, or rash. Contact your doctor immediately if you experience any of these symptoms. It should be administered by a healthcare professional, and you should monitor yourself or your baby for any signs of problems, such as breathing problems, jaundice, or allergic reactions. Do not try to administer this medication yourself. Be aware of the signs and symptoms of an allergic reaction, bleeding, respiratory distress, apnea, and liver problems and contact your doctor immediately if you experience any of these symptoms. Be aware of the signs and symptoms of apnea, such as a temporary cessation of breathing. Contact your doctor immediately if you experience any of these symptoms.
FAQs
Q 1. How long does Curosurf 120mg injection last?
The effects of Curosurf 120mg injection typically last for 3 to 5 days. However, some infants may need to receive additional doses.
Q 2. Is Curosurf 120mg injection safe for premature infants?
Curosurf 120mg injection is generally considered safe for premature infants. However, it is important to note that it can cause some side effects, such as bradycardia, hypotension, and hypoxemia.
Q 3. What happens if my infant needs more than one dose of Curosurf 120mg injection?
If your infant needs more than one dose of Curosurf 120mg injection, they may be at an increased risk of side effects. However, the benefits of receiving Curosurf 120mg injection often outweigh the risks.
Q 4. What are the long-term risks of Curosurf 120mg injection?
The long-term risks of Curosurf 120mg injection are not fully known. However, there is no evidence that it causes any long-term problems.
Q 5. What is the prognosis of Curosurf 120mg injection for infants with RDS?
The prognosis for infants with RDS has improved significantly in recent years. With proper treatment, most infants with RDS make a full recovery.
Q 6. How does Curosurf 120mg injection compare to other synthetic surfactants?
Curosurf 120mg injection is similar to other synthetic surfactants in terms of its effectiveness in treating RDS. However, it is known to cause less bradycardia and hypotension than other synthetic surfactants.
Fact Box of Curosurf 120mg Injection
Molecule name: Poractant alfa | Therapeutic class: Pulmonary surfactants |
Pharmacological class: Surfactants | Indications:Â 1. Respiratory distress syndrome (RDS)Â 2. Prevention of RDS |
References
- Chiesi Limited, Electronic medicines compendium (emc), [Revised on 16th Dec 2019] [Accessed on 23rd August 2023], https://www.medicines.org.uk/emc/product/6450/pil#gref
- Chiesi USA, Inc , US Food and Drug Administration, [Revised on 05/17/2021] [Accessed on Accessed on 23 August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2021/020744Orig1s043ltr.pdf
- Chao YS, Grobelna A; Curosurf (Poractant alfa) for the Treatment of Infants At Risk For or Experiencing Respiratory Distress Syndrome: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines [Internet]; Ottawa (ON): Canadian Agency for Drugs and Technologies in Health [Published on 18th Sep 2018] [Accessed on 23rd August 2023]; https://pubmed.ncbi.nlm.nih.gov/30860685/
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