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D-Pressin Spray
Prescription Required
Salt Composition : Desmopressin
Manufacturer : UNITED BIOTECH PVT LTD
Origin of Medicine : India
1 Bottle(s)
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Introduction to D-pressin Spray
D-Pressin Spray contains an active component as Desmopressin. It also known as DDAVP (1-desamino-8-D-arginine vasopressin), is a synthetic form of the hormone vasopressin. Vasopressin is naturally produced in the body by the hypothalamus and released from the pituitary gland. It plays a crucial role in regulating water balance, blood pressure, and urine production. D-Pressin Spray is the treatment of choice for central diabetes insipidus, a condition characterized by the inability of the body to properly regulate water balance. It helps reduce excessive thirst and urination by mimicking the action of vasopressin. It is sometimes used in the treatment of mild to moderate forms of VWD, a bleeding disorder caused by a deficiency or dysfunction of the von Willebrand factor. It stimulates the release of von Willebrand factor, which aids in clotting.
D-Pressin Spray can cause water retention, which may lead to a condition called hyponatremia (low sodium levels in the blood). It is important to monitor sodium levels during treatment, especially in individuals who are at an increased risk of hyponatremia, such as those with certain medical conditions or those taking medications that can affect sodium levels. This medication is primarily eliminated through the kidneys. Individuals with impaired kidney function may be at an increased risk of D-Pressin Spray accumulation and should be closely monitored while using the medication. If an individual has a known allergy or hypersensitivity to D-Pressin Spray or its components, its use should be avoided. Inform your healthcare provider about any pre-existing medical conditions, such as gastrointestinal disorders, liver disease, kidney disease, or other health conditions. These may require special precautions or adjustments in the use of this medication.
Uses of D-pressin Spray
D-Pressin Spray is used to treat the following:
- Diabetes Insipidus
- Nocturnal Enuresis (Bedwetting)
- Von Willebrand Disease (VWD)
Therapeutic Effects of D-pressin Spray
D-Pressin Spray is a medication that mimics the action of the hormone vasopressin in the body. Its therapeutic effect primarily focuses on regulating water balance and reducing excessive urine production. By increasing water reabsorption in the kidneys, it helps alleviate symptoms of conditions such as central diabetes insipidus and bedwetting (nocturnal enuresis). It can also aid in treating mild to moderate von Willebrand disease by promoting the release of von Willebrand factor, a clotting protein.
Interaction of D-pressin Spray with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with D-Pressin Spray, reducing effectiveness by causing undesirable side effects.
More Information about D-pressin Spray
- Store at room temperature, between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume D-pressin Spray
D-Pressin Spray can be administered orally in tablet form, as a nasal spray, or through injection. The specific usage instructions may vary depending on the condition being treated and the form of the medication. The nasal spray is administered by spraying into the nostrils, alternating nostrils with each dose.
Safety Advices for D-pressin Spray
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Pregnancy
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The safety of D-Pressin Spray during pregnancy has not been extensively studied, and limited information is available regarding its use in pregnant women. Therefore, the use of it during pregnancy should be carefully considered and evaluated by a healthcare professional, weighing the potential benefits against the potential risks.
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Breast Feeding
 ÂThe safety of D-Pressin Spray during breastfeeding has not been well studied, and limited information is available regarding its excretion into breast milk. As a result, it is recommended to exercise caution when using it while breastfeeding.
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Lungs
  D-Pressin Spray should be used with caution in individuals with lung conditions, as these conditions may affect the metabolism and elimination of the medication.
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Liver
  D-Pressin Spray should be used with caution in individuals with liver conditions. Close monitoring by a healthcare professional is necessary to ensure appropriate dosage and minimize potential risks.
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Alcohol
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D-Pressin Spray can increase the risk of hyponatremia (low sodium levels) when combined with alcohol. It is advisable to avoid or limit alcohol consumption while taking it.
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Driving
  D-Pressin Spray generally does not have a direct impact on alertness or motor function. However, individual responses may vary. If you experience dizziness, drowsiness, or other side effects that may impair your ability to drive or operate machinery, it is important to avoid these activities and seek medical advice.
Side Effects of D-pressin Spray
D-Pressin Spray cause some side effects like all medications, although not everyone will experience them.Â
Serious:
- Severe allergic reactions, including rash, itching, swelling, severe dizziness, or difficulty breathing
- Hyponatremia (low sodium levels)
- Fluid overload
- Severe headache or migraine
Common:
- Headache
- Nausea
- Stomach pain or cramps
- Flushing (redness or warmth of the skin)
- Nasal congestion or irritation (when using the nasal spray form)
- Runny nose or sneezing (when using the nasal spray form)
Word of Advice
Advice regarding D-Pressin Spray is to always consult with a healthcare professional before starting or making any changes to your medication regimen. They can assess your medical history, evaluate potential risks and benefits, provide personalized guidance, and monitor your progress throughout treatment. Additionally, closely follow the instructions and recommendations your healthcare provider gives, promptly report any unusual or concerning symptoms, and communicate openly about any concerns or questions you may have. Precautions should be taken when using this medication in patients with liver or kidney impairment, as dosage adjustments or special monitoring may be required. Pregnant and breastfeeding individuals should consult with healthcare professionals before using this medication. Your healthcare professional is the best resource for ensuring safe and effective medication use.
FAQs
Q 1. Can D-Pressin Spray be used for the treatment of diabetes insipidus in pregnancy?
The use of D-Pressin Spray for diabetes insipidus during pregnancy requires careful evaluation by a healthcare provider. The benefits and risks should be assessed, taking into consideration the specific needs of the individual and the potential effects on both the mother and the fetus. Close monitoring of fluid balance, electrolyte levels, and blood pressure is crucial during pregnancy when using it.
Q 2. Is D-Pressin Spray safe for long-term use?
D-Pressin Spray can be used for long-term treatment in certain conditions, such as central diabetes insipidus. However, the duration of treatment and the need for continued use should be determined by a healthcare provider based on individual circumstances. Regular monitoring of fluid balance, electrolyte levels, and kidney function is important for long-term users of it.
Q 3. What are the common side effects of D-Pressin Spray?
Common side effects of D-Pressin Spray may include headaches, nausea, stomach pain or cramps, flushing, nasal congestion or irritation (with nasal spray), and runny nose or sneezing (with nasal spray). It is important to note that not everyone will experience these side effects, and their severity may vary.
Q 4. Can D-Pressin Spray be used to prevent altitude sickness or help with acclimatization at high altitudes?
While D-Pressin Spray has been studied for its effects on water balance and fluid retention, it is not a recommended or approved treatment for altitude sickness or acclimatization. Altitude sickness prevention and acclimatization strategies typically involve gradual ascent, proper hydration, and adequate rest.
Q 5. Is D-Pressin Spray addictive?
D-Pressin Spray is not considered addictive. It does not produce the same effects as addictive substances, such as causing dependence or cravings. However, it is important to use this medication as prescribed by a healthcare provider and to follow the recommended dosage and duration of treatment.
Fact Box of D-pressin Spray
Molecule name: Desmopressin | Therapeutic class: Vasopressin analogue |
Pharmacological class: Antidiuretic
| Indications:Â 1. Diabetes Insipidus 2. Nocturnal Enuresis (Bedwetting) 3. Von Willebrand Disease (VWD) |
References
- Aspire Pharma; Electronic Medicines Compendium; [Revised: 2020] [Accesses: 17/July/2023]; https://www.medicines.org.uk/emc/files/pil.11939.pdf
- Ferring Pharmaceuticals Ltd; Electronic Medicines Compendium; [Revised:2020] [Accessed: 17/July/2023]; https://www.medicines.org.uk/emc/product/3795/pil
- TS McCarty, Shah AD; Desmopressin; NCBI Bookshelf; [Revised:2020] [Accessed:17/July/2023] ; https://www.ncbi.nlm.nih.gov/books/NBK554582/
- Johan Vande Walle et al; Desmopressin 30 years in clinical use: A safety review; [Revised: 2007] [Accessed: 17/July/2023] ; https://pubmed.ncbi.nlm.nih.gov/18690973/
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