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  ÂDexem Injection 0.5ml
Prescription Required
Salt Composition : Dexmedetomidine Hcl
Manufacturer : THEMIS MEDICARE
Origin of Medicine : India
1 Ampoule(s) Of 0.5ml
Introduction to Dexem Injection 0.5ml
Dexem injection 0.5ml contains an active substance called dexmedetomidine, which belongs to a group of medications called sedatives. It is used to provide sedation (a state of calm, drowsiness, or sleep) for adult patients in hospital intensive care settings or awake sedation during different diagnostic or surgical procedures.
It is not recommended to use this medicine if you are allergic to dexmedetomidine or any of the other ingredients. Additionally, inform your doctor if you have disorders of heart, or if you experience very low blood pressure that does not respond to treatment. Avoid this medication if you have recently had a stroke or any other serious condition impacting the blood supply to the brain. Prioritize consulting your healthcare provider to determine the suitability of this medicine for your specific health conditions.
Uses of Dexem Injection 0.5ml
- For patients in intensive care settings (sedation)
- For diagnostic or surgical procedures (awake sedation)
Therapeutic Effects of Dexem Injection 0.5ml
Dexem injection 0.5ml acts on alpha-2 adrenergic receptors, inhibits the release of a chemical substance called norepinephrine, and terminates the spread of pain signals in the brain, providing calm and relaxation. When given slowly at lower and moderate doses, it mainly targets one type of alpha1 receptor, providing a soothing effect. However, at higher doses or when given quickly, it can affect both types of alpha1 and alpha2 receptors.
Interaction of Dexem Injection 0.5ml with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with dexem injection 0.5ml and cause undesirable side effects.
More Information about Dexem Injection 0.5ml
- Keep dexem injection 0.5ml out of sight and reach of children.
- Store at room temperature.
How to consume Dexem Injection 0.5ml
Dexem injection 0.5ml is given only in a hospital set up by a trained healthcare provider. It will be given to you as an injection into your muscle (intramuscularly) for adults in the arm and children in the thigh. Your doctor will decide your most apt dosage based on age, body weight, and physical circumstances.
Safety Advices for Dexem Injection 0.5ml
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Pregnancy
 ÂTell your doctor if you are pregnant or planning to get pregnant before taking this medicine. It will be given to you if clearly needed.
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Breast Feeding
 ÂTell your doctor if you are breastfeeding before taking this medicine. It will be given to you if clearly needed.
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Lungs
 ÂThe safety of dexem injection 0.5ml in lung patients is unknown. Hence, inform your doctor if you have any lung-related problems before starting the treatment.
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Liver
 ÂDexem injection 0.5ml is used cautiously in patients with impaired liver function. Inform your doctor if you suffer from any serious liver disorder.
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Alcohol
 ÂDrinking alcohol during the treatment with dexem injection 0.5ml may enhance the sedative effect. Hence, it is not advised to take alcohol.
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Driving
 ÂIt is not recommended to drive or operate heavy machines while undergoing dexem injection 0.5ml treatment. Consult your doctor to know when it is safe to resume these activities, ensuring that the effects of the injection have completely worn off.
Side Effects of Dexem Injection 0.5ml
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.Â
Serious:
- Chest pain
Common:
- Abnormal heart rate
- High or low blood pressure
- Change in breathing pattern
- High or low blood sugar
- Nausea, vomiting, dry mouth
- Restlessness
- Fever
Word of Advice
Inform your healthcare provider about any symptoms occurring within 48 hours after the treatment with dexem injection 0.5ml injection, such as nervousness, agitation, headaches (associated with infusions lasting over 6 hours), weakness, confusion, excessive sweating, weight loss, abdominal pain, salt cravings, diarrhea, constipation, dizziness, or light-headedness promptly.
Adhere strictly to the directed safety measures provided by your healthcare provider. It is important to attend all scheduled appointments and follow-up visits to monitor the response to dexem injection 0.5ml treatment.
FAQs
Q 1. Can I drive or operate heavy machines while undergoing dexem injection 0.5ml treatment?
No, it is unsafe to drive or operate heavy machinery during treatment. Consult your doctor to determine when it is safe to resume such activities after ensuring the effects of the medication have completely gone.
Q 2. What should I do if I experience chest pain while on dexem injection 0.5ml?
Chest pain is a serious side effect. Immediately Inform your healthcare provider promptly if you experience chest pain during the treatment.
Q 3. Is it safe to consume alcohol during dexem injection 0.5ml treatment?
No, drinking alcohol during treatment may enhance the sedative effect. It is not advised to consume alcohol while on dexem injection 0.5ml.
Q 4. How is dexem injection 0.5ml administered?
Dexem injection 0.5ml is given only in a hospital set up by a trained healthcare provider. It is given to you as an infusion (drip) into your veins. Your doctor will decide your most apt dosage based on age, body weight, and physical circumstances.
Q 5. What side effects should I report to my doctor while taking dexem injection 0.5ml?
Serious side effects, such as abnormal heart rate, high or low blood pressure, changes in breathing patterns, high or low blood sugar, and common side effects like nausea, vomiting, dry mouth, restlessness, and fever, should be reported to your healthcare provider while taking dexem injection 0.5ml.
Fact Box of Dexem Injection 0.5ml
Molecule Name: Dexmedetomidine hydrochloride | Therapeutic class: Sedatives |
Pharmacological class:Â Central alpha-2 adrenergic agonist | Indications: 1. For patients in intensive care settings (sedation) 2. For diagnostic or surgical procedures (awake sedation) |
References
- Orion Corporation, Electronic medicines compendium (EMC), [Revised on Jan 2021] [Accessed on Nov 2023], https://www.medicines.org.uk/emc/files/pil.4783.pdf
- Hospira, Inc, US, Inc, US Food and Drug Administration (FDA), [Revised on June 2013] [Accessed on Nov 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021038s021lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, General Anaesthetics, 7th edition, 2013, 384.
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, General Anaesthetics and Therapeutic gases, 12th edition, 2011, 548-549.
Disclaimer
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