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Dorucin 50mg Injection
Prescription Required
Salt Composition : Liposomal Doxorubicin
Manufacturer : APRAZER HEALTHCARE PVT LTD
Origin of Medicine : India
1 Vial(s) Of 25ml
Introduction to Dorucin 50mg Injection
Dorucin 50mg Injection is an anticancer medication that contains the active constituent doxorubicin encapsulated in a closed lipid sphere (liposome). Cancer is a disease in which cells multiply in an uncontrolled and abnormal manner. This medication treats breast cancer, ovarian cancer, multiple myeloma (cancer of white blood cells called plasma cells), and AIDS-related Kaposi’s sarcoma. Â
People with HIV infection have the highest risk of Kaposi’s sarcoma (cancer that forms in the lining of the lymph and blood vessels). Dorucin 50mg Injection may be given alone or in combination with other anticancer medicines. This medication is not recommended for adolescents and children.Â
Use effective birth control during the treatment and at least six months after the last dose. It is important to tell your doctor if you are allergic to peanuts or soya if you are receiving medicines for heart or liver disorders, has diabetes, Kaposi’s sarcoma, or have oral problems before taking Dorucin 50mg Injection.
Uses of Dorucin 50mg Injection
- Breast cancer
- Ovarian cancer
- Multiple myeloma
- AIDS-related Kaposi’s sarcoma
Therapeutic Effects of Dorucin 50mg Injection
Doxorubicin inhibits the activity of the enzyme topoisomerase II, which is involved in the DNA (genetic material) multiplication of cancer cells. This prevents the growth and multiplication of cancer cells.Â
The unique formulation process of Dorucin 50mg Injection increases the time this medicine is circulating in the blood. It also helps deliver drugs from blood to the cancerous tissue rather than the healthy tissue.
Interaction of Dorucin 50mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutrition or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Dorucin 50mg Injection and can cause undesirable side effects.Â
More Information about Dorucin 50mg Injection
- Keep Dorucin 50mg Injection out of sight and reach of children.
- Store refrigerated at 2°C - 8°C. Do not freeze.
How to consume Dorucin 50mg Injection
Your dose and frequency of administration will be decided by your physician based on your disease condition and other factors. It will be given to you by a healthcare professional. Do not self-administer.Â
Safety Advices for Dorucin 50mg Injection
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Pregnancy
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Dorucin 50mg Injection may harm the unborn baby. You need to tell your physician if you are pregnant or planning to get pregnant before taking this medicine.Â
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Breast Feeding
 ÂStop breastfeeding before starting treatment with Dorucin 50mg Injection. You need to tell your physician if you are breastfeeding before taking this medicine.Â
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Lungs
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It is unknown whether Dorucin 50mg Injection can be given to patients with lung diseases. Please consult your physician if you have any lung problems.Â
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Liver
  You need to tell your physician if you have any liver disorders before taking Dorucin 50mg Injection.
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Alcohol
 ÂIt is not known whether it is safe to consume alcohol with Dorucin 50mg Injection. Please consult your doctor.
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Driving
  Dorucin 50mg Injection may cause tiredness or sleepiness. Avoid driving if you are unwell. Please consult your doctor for more advice.Â
Side Effects of Dorucin 50mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.Â
Serious:
- Fever, tiredness, bruising or bleeding
- Severe diarrhea, sores in mouth, nausea, vomiting
- Lung infections, shortness of breath
- Severe stomach pain
- Severe weakness
Common:
- Low blood cell counts
- Hair loss
- Decreased appetite
- Skin rashes
- Pain in the muscles and joints
- Constipation
- Feeling confused, difficulty sleeping
- Headache, dizziness, sleepiness
- Change in taste
- High or low blood pressure
- Excessive sweating
- Pain when passing urine
- Weight loss
- Muscle spasms
- Fast heartbeatSide effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious:
- Fever, tiredness, bruising or bleeding
- Severe diarrhea, sores in mouth, nausea, vomiting
- Lung infections, shortness of breath
- Severe stomach pain
- Severe weakness
Common:
- Low blood cell counts
- Hair loss
- Decreased appetite
- Skin rashes
- Pain in the muscles and joints
- Constipation
- Feeling confused, difficulty sleeping
- Headache, dizziness, sleepiness
- Change in taste
- High or low blood pressure
- Excessive sweating
- Pain when passing urine
- Weight loss
- Muscle spasms
- Fast heartbeat
Word of Advice
Inform the doctor if the patient has allergic reactions, diabetes, blood pressure, kidney, liver diseases before taking this medication. Blood glucose levels, blood pressure, and liver and kidney function should be monitored regularly while taking this medication. Don't stop this medication without the proper advice of the doctor. Avoid making plans for pregnancy or during pregnancy, as this medication can cause harmful effects on the developing baby. Avoid driving after taking this medication because it causes dizziness and lack of concentration.
FAQs
Q 1. What is the use of Dorucin 50mg Injection?
This medication is used to treat breast cancer, ovarian cancer, multiple myeloma (cancer of white blood cells called plasma cells) and AIDS-related Kaposi’s sarcoma.
Q 2. Is it safe to use Dorucin 50mg Injection while driving?
No, it is unsafe to use this medication while driving and handling heavy machinery as it causes lack of concentration and alertness.
Q 3. How does Dorucin 50mg Injection work?
It damages the genetic material (DNA) of the cancer cells and stops their growth and multiplication
Q 4. What are the side effects of Dorucin 50mg Injection?
The common side effects of these medications are nausea, vomiting, rash, weakness, low blood platelets, Fatigue, Fever, Loss of appetite, Anemia, and Constipation.
Q 5. Is it safe to use Dorucin 50mg Injection during pregnancy?
It is unsafe to use this medication in patients planning for pregnancy or during pregnancy and breastfeeding mothers as it causes harmful effects for the baby.
Fact Box of Dorucin 50mg Injection
| Molecule Name: Liposomal Doxorubicin | Therapeutic effects: Antineoplastics |
| Pharmacological class: Anthracyclines | Indications: 1. Breast cancer 2. Ovarian cancer 3. Multiple myeloma 4. AIDS-related Kaposi’s sarcoma |
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1714.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 867.
- Baxter Holding BV, European medicines agency (ema), [Revised on May 2006] [ Accessed on 4th Dec 2021], https://www.ema.europa.eu/en/documents/product-information/caelyx-pegylated-liposomal-epar-product-information_en.pdf
- Ben Venue Laboratories, Inc, US Food and Drug Administration, [Revised on May 2007] [ Accessed on 4th Dec 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/050718s029lbl.pdf
Disclaimer
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