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Ematra Softgel Capsule
Prescription Required
Salt Composition : Tretinoin
Manufacturer : EMCURE PHARMACEUTICALS LTD
Origin of Medicine : India
100 Capsule(s) In A Bottle
Introduction to Ematra Softgel Capsule
Ematra capsule is an antineoplastic drug with an active ingredient called Tretinoin. It belongs to the medication class known as retinoids, similar to vitamin A. It is used to treat a kind of blood issue called acute promyelocytic leukemia which slow down the growth of diseased blood cells.Â
Do not take this medicine if you are allergic to Tretinoin or any of the other substances of this medicine if you take other medicine like vitamin A, tetracyclines, or retinoids (Isotretinoin, Acitretin, Tazarotene). Avoid taking peanuts and soya, as this medicine contains soya bean oil. Talk to your doctor if you have other health conditions or ever had or have mental health problems like depression, mood change, or aggressive behavior because taking this medicine may affect your mood. Â
Before taking this medicine, inform your healthcare professional if you are planning to get pregnant or pregnant or breastfeeding. Should not get pregnant even after stopping the medicine for one month. Use effective contraception. Notify your doctor if you are allergic or intolerant to some sugar, as this medicine contains sorbitol. There is limited information available on the use of this medicine in children. Contact your doctor for more information. Report to your doctor immediately if you experience any side effects such as fever, chest or back pain, difficulty breathing, or fever.
Uses of Ematra Softgel Capsule
- Acute promyelocytic leukemia
Therapeutic Effects of Ematra Softgel Capsule
Ematra capsule binds to the fusion protein and breaks down the protein, making the immature blood cells differentiate into mature white blood cells (WBC). This helps restore normal blood cell production and reduces the number of abnormal cells present in blood and bone marrow.Â
Interaction of Ematra Softgel Capsule with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications such as Low dose progestogens (birth pill), Isotretinoin, Acitretin, Tazarotene, and other medications may interact with Ematra capsule and can cause undesirable side effects.Â
More Information about Ematra Softgel Capsule
- Keep out of sight and reach of pets and children
- Store protected from light at a temperature not exceeding 30°C.
- Ematra capsule treatment can take three months or longer. Do not stop until your doctor advises.
How to consume Ematra Softgel Capsule
Take Ematra capsule as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking Ematra capsule if your doctor advises you to stop.
Safety Advices for Ematra Softgel Capsule
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Pregnancy
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Ematra capsule is unsafe to use during pregnancy as it may harm the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment.Â
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Breast Feeding
 ÂTaking Ematra capsule while breastfeeding may be unsafe because it may affect the child. Do not breastfeed for at least four months after the treatment. Therefore, talk with your doctor to get more information.Â
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Lungs
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It is unknown whether Ematra capsule is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience difficulty in breathing or any lung-related symptoms.
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Liver
  Only limited information is available about the usage in liver condition patients. So it is unknown whether Ematra capsule is safe for patients with liver problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.
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Alcohol
 ÂIt is unknown whether consuming alcohol while taking a Ematra capsule is safe. Please speak with your physician.
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Driving
  While taking Ematra capsule, driving or using machines is unsafe because it may cause dizziness or severe headache. Talk to your doctor for more information.Â
Side Effects of Ematra Softgel Capsule
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Difficulty in breathing
- Fever Coughing
- Dizziness
- Pain in chest and abdomen
- Severe headache
- Severe stomach pain that spread to back (the sign of pancreatitis)
- Dark lumpy makings on the skin
- Swelling in leg
- Double vision
- Ringing in the ear and headache
- Sudden migraine
Common
- Hair loss
- Irregular heartbeat
- Joint pain
- Bone pain
- Skin rashes, itching, redness, inflammation
- Dryness in skin, mouth, nose
- Respiratory failure
- Unusual sweating
- Mood swings
- Numbness or tingling on hands or feet
- Constipation
- High levels of blood creatinine or blood fats
Word of Advice
Inform your doctor about the side effect you are experiencing; your doctor may change the dosage of Ematra capsule or give you some additional medicine to reduce the side effects. Even though you didn't notice a change in your mood and, behavior, it is advised you inform your friends and family that this medicine could affect your mood and behavior. Discuss with your doctor about effective contraception methods to avoid getting pregnant. Women should take pregnancy tests every four months while under treatment. Notify your doctor immediately if you become pregnant while under treatment; your doctor will provide you with the right treatment. Do not consume other medications unless your doctor prescribes them.
FAQs
Q 1. Why use effective contraception during the treatment of Ematra capsule?
To avoid unwanted pregnancy, it is advised to use effective contraception. Inform your doctor if you become pregnant while under the treatment of Ematra capsule; your doctor may pick the right treatment. Also, it is better to discuss effective contraception with your doctor.
Q 2. What are the different forms of Ematra capsule available?
Ematra capsule is primarily available in two forms such as topical creams and gels and oral capsules.
Q 3. Do Ematra capsule cream and capsules have the same medical use and impact?
No, Ematra capsule cream is used as a topical medicine to treat skin conditions (acne, rashes, etc.), whereas the capsule is used to reduce the number of abnormal cells.
Q 4. Should I double-dose Ematra capsule if I missed the dose?
No, you should not double-dose the Ematra capsule even if you missed the regular dose. If you forgot to take the dose, take one as soon as you remember. If you double-dose the medicine, contact your doctor immediately.
Q 5. Is that okay to take Ematra capsule for kidney disease?
Only limited information is available about the usage of Ematra capsule in kidney patients. So it is advised to inform the patient of the history with your doctor before starting the treatment.
Fact Box of Ematra Softgel Capsule
| Molecule Name: Tretinoin | Therapeutic class: Anti-neoplastics |
| Pharmacological class: Retinoids | Indications: Acute promyelocytic leukemia |
References
- Neon Healthcare Ltd, Electronic Medicines Compendium(EMC), [Revised on Dec 2020], [Accessed on 26th April 2023], Tretinoin 10mg soft capsules - Patient Information Leaflet (PIL) - (emc) (medicines.org.uk)
- Glenmark Pharmaceuticals, [Revised on Dec 2018] [Accessed on 26th April 2023], https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=264138c1-9e5f-45ef-be87-79ca97c989d9&type=display
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
Disclaimer
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