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Encoxel 60mg Injection
Prescription Required
Salt Composition : Enoxaparin
Manufacturer : CELON LABORATORIES LTD
Origin of Medicine : India
1 Prefilled Syringe(s) Of 0.6ml
Introduction to Encoxel 60mg Injection
Encoxel 60mg Injection is an anticoagulant drug belonging to the category of low molecular weight heparin (LMWH). It contains the active ingredient Enoxaparin. It is used to treat severe blood clots. This drug also prevents the occurrence of deep vein thrombosis in abdominal surgery, hip replacement surgery, knee replacement surgery, and in people with severe movement restrictions. This injection prevents further heart complications in patients with unstable angina and non-Q wave myocardial infarction.
Encoxel 60mg Injection is not recommended for patients with active bleeding, hypersensitivity, or allergies to the active compound, as well as those with a history of heparin-induced thrombocytopenia before taking Encoxel 60mg Injection, tell your physician if you are allergic to Enoxaparin, heparin, benzyl alcohol, or pork products.Â
Your healthcare provider will regularly monitor you for signs of bleeding. Inform your healthcare practitioner if you are diagnosed with kidney problems. It is not recommended for use in children and adolescents below 18 years.Â
Encoxel 60mg Injection is not recommended if you undergo procedures like neuraxial anaesthesia or spinal puncture. It is recommended to monitor older adults and patients with low weight for increased risk of bleeding.
Tell your physician if you suspect pregnancy, breastfeeding, or planning to have a baby. Encoxel 60mg Injection may increase the chance of bleeding in pregnant women with artificial heart valves, and hence, close monitoring must be done.Â
Consult your doctor for more advice before starting Encoxel 60mg Injection medication, it is recommended not to take any hemostatic drugs unless absolutely necessary. It is needed to inform your physician about all the drugs you are taking, including herbal and vitamin supplements.
Uses of Encoxel 60mg Injection
Encoxel 60mg Injection is used in the treatment of the following:
- Deep vein thrombosis
- Prophylaxis of venous thrombo-embolism
- Unstable angina
- ST-segment Elevation Myocardial Infarction (STEMI)
- Prevention of blood clots during surgeries
Therapeutic Effects of Encoxel 60mg Injection
Encoxel 60mg Injection binds to the antithrombin to form a complex. Antithrombin is a protein that blocks the formation of abnormal blood clots. This drug mainly prevents the activation of factor Xa, eventually preventing clot formation. It is commonly used for the prevention and treatment of conditions associated with increased risk of blood clots.Â
Interaction of Encoxel 60mg Injection with other drugs
Some medicinal products that affect haemostasis should be discontinued before starting Encoxel 60mg Injection therapy unless absolutely necessary. If a combination is required, Encoxel 60mg Injection should be used with careful clinical and laboratory monitoring.Â
These products include systemic salicylates, acetylsalicylic acid at anti-inflammatory doses, NSAIDs like ketorolac, other thrombolytics such as alteplase, reteplase, streptokinase, tenecteplase, urokinase, and other anticoagulants.Â
Always inform your doctor about any medicines or supplements you are taking, as they may interact with Encoxel 60mg Injection.
More Information about Encoxel 60mg Injection
- Store Encoxel 60mg Injection below 25 °C.
- Do not freeze
- Keep it out of reach from children.
- Protect them from light and moisture.
How to consume Encoxel 60mg Injection
Encoxel 60mg Injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered as an intravenous injection into a vein. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Safety Advices for Encoxel 60mg Injection
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Pregnancy
 ÂBefore beginning therapy with Encoxel 60mg Injection, tell your doctor if you are pregnant, suspect you are pregnant, or are planning to become pregnant. It is not known that Encoxel 60mg Injection interferes with pregnancy.
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Breast Feeding
 ÂIt is unknown if Encoxel 60mg Injection is excreted unaltered in breast milk. Please consult your doctor before breastfeeding.
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Lungs
 ÂIt is unknown whether Encoxel 60mg Injection is safe for patients with lung problems. Consult your doctor if you have lung disease before starting the treatment.
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Liver
 ÂInform your doctor if you have liver disease because of Encoxel 60mg Injection should be used cautiously with a liver condition.
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Alcohol
 ÂIt is unknown if consuming alcoholic beverages while taking Encoxel 60mg Injection is safe. Please consult with your physician.
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Driving
 ÂIt is safe to travel, drive a car, or operate heavy machinery after receiving Encoxel 60mg Injection. Encoxel 60mg Injection does not impair alertness or coordination.
Side Effects of Encoxel 60mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious side effects of Encoxel 60mg Injection are:
- Severe allergic reactions (swelling of lips, tongue, or throat, difficulty breathing, or swallowing)
- Too much bleeding (weakness, being pale, dizziness with headache, or unexplained swelling)
- Blockage of blood vessels (pain, redness, or swelling in the legs, or coughing up blood)
- Rash of dark red spots under the skin
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Common side effects of Encoxel 60mg Injection are:
- Bleeding
- Bruising more easily
- Low blood cell counts
- Headache
- Itchy red skin
- Edema
- Pain at the injection site
- Pink patches on the skin
Word of Advice
Encoxel 60mg Injection can cause bleeding and many undesirable side effects; hence it is advised to get adequate rest during the treatment. Eat a well-balanced diet. Apply a cool compress at the injection site to reduce pain and irritation. Encoxel 60mg Injection should not be stopped suddenly without first talking to your doctor because doing so may raise your risk of blood clots.Â
Aspirin and other non-steroidal anti-inflammatory medicines (NSAIDs) may increase the risk of bleeding when combined with Encoxel 60mg Injection, so it is not recommended to take them without first talking to your doctor. Keep away from activities that put you at higher risk of bleeding or getting hurt, like contact sports and activities.Â
Foods high in Vitamin K may have an impact on blood clotting and may interfere with the way anticoagulant drugs like Encoxel 60mg Injection. It is recommended to eat leafy green vegetables, asparagus, Brussels sprouts and soybean oil in moderation. It is advised to monitor your platelet count regularly.
FAQs
Q 1. Who should not take Encoxel 60mg injection?
Encoxel 60mg Injection is not recommended for people suffering from active major bleeding or a history of hypersensitivity to Encoxel 60mg Injection, heparin, Benzyl alcohol, or pork products. This drug is also not advised for people with a history of heparin-induced thrombocytopenia in the past hundred days.
Q 2. What should you not take with Encoxel 60mg injection?
When taking Encoxel 60mg Injection, it's important to avoid certain medications, supplements, and activities that may increase the risk of bleeding or interact with the anticoagulant effects of Encoxel 60mg Injection includes other anticoagulants, non-steroidal anti-inflammatory drugs, and anti-platelets.
Q 3. Is there any most common side effects of Encoxel 60mg injection?
The most common adverse reactions of Encoxel 60mg injection are bleeding, anemia, thrombocytopenia, diarrhea, nausea, fever, edema, breathlessness, confusion, and pain at the injection site.
Q 4. How long should Encoxel 60mg Injection treatment continue?
The duration of Encoxel 60mg Injection treatment depends on the underlying condition being treated, the risk of clotting, and individual patient factors. Treatment may be short-term (e.g., during hospitalisation or surgical procedures) or long-term for chronic conditions such as DVT or PE.
Q 5. When should you report to the doctor while using Encoxel 60mg Injection?
Contact your physician directly if you experience severe allergic reactions like the spelling of lips, tongue, throat, difficulty breathing or swallowing, unexplained swelling, painful Rash, chest pain, or blood in the cough during the treatment with Encoxel 60mg Injection.
Q 6. How should Encoxel 60mg Injection be stored?
Encoxel 60mg Injection should be stored at room temperature (between 68°F to 77°F or 20°C to 25°C) away from light and moisture. It should be kept out of the reach of children and not be frozen. Unused portions of Encoxel 60mg Injection solution should be discarded according to the manufacturer's instructions.
Fact Box of Encoxel 60mg Injection
Molecule Name: Enoxaparin | Therapeutic class: Anticoagulant |
Pharmacological class: Low molecular weight heparin (LMWH) | Indications: Treat and prevent blood clot |
References
- Rovi Biotech Limited, European Medicine Consortium (EMC), [Revised on Nov 2018], Available at: https://www.medicines.org.uk/emc/files/pil.9330.pdf [Accessed on 27th May 2023].
- Sanofi, [Revised on Apr 2022] [Accessed on 27th May 2023], https://products.sanofi.us/lovenox/lovenox.pdf
- Clexane® syringes 100MG/ML solution for Injection - HPRA. [Revised on May 2022], Available at: https://www.hpra.ie/img/uploaded/swedocuments/7900ad74-3eb7-41a2-be4c-3b757cb841ec.pdf [Accessed on 27th May 2023].
- KD Tripathi, Essentials of Medical Pharmacology, Drugs Affecting Coagulation, Bleeding and Thrombosis, 8th Edition, 2019, 659-681.
- https://www.ema.europa.eu/en/documents/product-information/inhixa-epar-product-information_en.pdf
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