All Substitutes
Loading...
Disclaimer
Did you find this information helpful?
  Â
Endoxan 50mg Tablet
Prescription Required
Salt Composition : Cyclophosphamide
Manufacturer : ZYDUS CADILA
Origin of Medicine : India
10 Tablet(s) In A Strip
Introduction to Endoxan 50mg Tablet
Endoxan 50mg tablet is a chemotherapy drug containing the active constituent cyclophosphamide. It is used to treat various malignancies (abnormal production of cells is called cancer; if they spread, those are called malignancies). This tablet can be used to treat malignant lymphomas (cancers that start from the lymphatic system of the body- vessels, fluid, and lymphoid tissue) such as Hodgkin’s disease, lymphocytic lymphoma, and mixed-cell type lymphoma. Â
It treats leukemias, neuroblastoma, ovarian cancer, retinoblastoma, and breast carcinoma. It can also treat Minimal Change Nephrotic syndrome in pediatric patients (kidney disease in which large quantities of protein are lost in urine). Endoxan 50mg tablet is contraindicated in pregnancy, patients with acute infections, urinary tract infections, urinary outflow obstruction, and bone marrow disorders. Â
Treatment with this medicine may lead to immune suppression, bone marrow failure, cardiotoxicity, renal toxicity, pulmonary toxicity, and secondary malignancies. Inform your doctor if you have pre-existing kidney disease, immune conditions, cardiac disorders, or liver diseases.
Uses of Endoxan 50mg Tablet
- Malignant lymphomas
- Leukemias
- Retinoblastoma
- Carcinoma of breast
- Ovarian cancer
- Mycosis fungoides
- Minimal Change Nephrotic Syndrome in Pediatric Patients
Therapeutic Effects of Endoxan 50mg Tablet
Endoxan 50mg Tablet slows or stops the growth of cancer cells by damaging the hereditary material (DNA and RNA) of the cancer cells. In nephrotic syndrome, it works by suppressing the body’s immune system.
Interaction of Endoxan 50mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Endoxan 50mg tablet and cause potential side effects.Â
More Information about Endoxan 50mg Tablet
Keep Endoxan 50mg Tablet out of sight and reach of children. Store tablets below or at 25°C. Do not freeze.
How to consume Endoxan 50mg Tablet
Take Endoxan 50mg Table in the dose and duration prescribed by your physician. Swallow the tablets whole and intact. Do not chew or crush the tablets. Avoid exposure to broken tablets; if contact occurs, wash your hands immediately.
Safety Advices for Endoxan 50mg Tablet
 Â
Pregnancy
 Â
Endoxan 50mg Tablet may cause fetal harm when administered to a pregnant woman. Inform your physician if you are pregnant or planning to get pregnant before taking this medication. Your physician will instruct you to take it when it is necessary.
 Â
Breast Feeding
 ÂAvoid Endoxan 50mg tablet medication if you are breastfeeding. Ask for a doctor’s advice.
 Â
Lungs
 Â
It is unknown whether Endoxan 50mg tablet can be given to lung failure patients. Inform your doctor if you have any lung diseases.Â
 Â
Liver
  Endoxan 50mg Tablet should be used with caution in patients with liver disease. A dose adjustment of this Tablet may be needed. Please consult your doctor.
 Â
Alcohol
 ÂIt is unsafe to consume alcohol with Endoxan 50mg Tablet. Please consult your doctor for more advice.Â
 Â
Driving
  The patient undergoing treatment with this medicine may have dizziness, and blurred vision. Consult your doctor before driving and handling heavy machines.
Side Effects of Endoxan 50mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.Â
Serious:
- Infections
- Immune suppression
- Blood disorders
- Allergic reactions
- Abnormal liver function
- Inflammation of the bladder
- Kidney diseases
- blood in urine
- sterility
- impaired wound healing
Common:
- Nausea, vomiting
- Low white blood cell count
- Diarrhea
- Hair loss
- Fever
- Weakness
- Inflammation
- Dizziness
- Blurred vision
- amenorrhea
Word of Advice
Inform the doctor if the patient has any kidney, liver, or heart problems and medication taken for different medical conditions. It causes immune suppression, and hence inform the doctor if there are any immunity-related problems. Endoxan 50mg Tablet should be avoided in pregnant women and breastfeeding mothers. The patient undergoing treatment with this medicine may have dizziness and blurred vision. Consult your doctor before driving and handling heavy machines.
FAQs
Q 1. Can Endoxan 50mg Tablet cause infertility?
Yes, Endoxan 50mg Tablet can cause infertility in both men and women and hence consult the doctor before taking this medication.
Q 2. Is Endoxan 50mg Tablet a chemotherapy medication?
Yes, Endoxan 50mg Tablet is a chemotherapy medicine, and it works by killing cancer cells. It prevents the spreading of cancer cells to different parts.
Q 3. Can Endoxan 50mg Tablet cause weight loss?
Yes, Endoxan 50mg Tablet causes weight loss due to reduced appetite, and consult the doctor if there is excessive weight loss.
Q 4. Can Endoxan 50mg Tablet be used during pregnancy?
No, it is highly unsafe to use Endoxan 50mg Tablet during pregnancy as they can cause harmful effects on the developing baby.
Q 5. Can Endoxan 50mg Tablet cause hair loss?
Yes, Endoxan 50mg Tablet can cause hair loss, and consult the doctor if there is excessive hair loss.
Q 6. Can I take Endoxan 50mg Tablet while driving?
No, it is not recommended while driving because it cause dizziness and patients may lack concentration and alertness.
Fact Box of Endoxan 50mg Tablet
| Molecule Name: Cyclophosphamide | Therapeutic Class: 1. Anti-cancer 2. Antirheumatic 3. Immunomodulators |
| Pharmacological Class: Alkylating agent | Indications: 1. Malignant lymphomas 2. Treat certain cancers such as eye, blood, breast, and ovarian cancer. 3. Minimal Change Nephrotic Syndrome in Pediatric Patients
|
References
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.
- Baxter, Electronic medicines compendium (emc), [ Revised on Dec 2016] [ Accessed on 8th April 2021], https://www.medicines.org.uk/emc/product/1813/smpc
- Baxter, US Food and Drug Administration, [ Revised on May 2013] [ Accessed on 7th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
