All Substitutes
Loading...
Disclaimer
Did you find this information helpful?
  Â
Endoxan N 1gm Injection
Prescription Required
Salt Composition : Cyclophosphamide
Manufacturer : ZYDUS CADILA
Origin of Medicine : India
1 Vial(s)
Introduction to Endoxan N 1gm Injection
Endoxan N 1gm Injection is a widely used chemotherapy medication that contains cyclophosphamide as its active constituent. Classified under alkylating agents, this injection plays a pivotal role in the treatment of various cancers, including lymphomas, leukaemias, and certain solid tumours. Additionally, it is employed in managing autoimmune disorders like lupus and rheumatoid arthritis, demonstrating its versatility in medical applications.
Endoxan N 1gm Injection works by interfering with the DNA replication process, thereby halting the growth of rapidly dividing cancer cells. While highly effective, its administration requires careful medical supervision due to potential side effects. Commonly experienced adverse reactions include nausea, hair loss, and reduced immunity. It is essential to discuss preventive measures with your healthcare provider, such as staying hydrated and monitoring blood counts regularly.
Patients should use this injection strictly under a doctor’s guidance, as it carries specific warnings and contraindications. It is not recommended for individuals with severe kidney or liver impairment, active infections, or hypersensitivity to cyclophosphamide. Pregnant or breastfeeding women should also avoid its use due to potential harm to the fetus or infant. Always consult your healthcare provider for tailored advice before starting treatment with Endoxan N 1gm Injection.
Uses of Endoxan N 1gm Injection
- Malignant lymphomas
- Leukemias
- Retinoblastoma
- Carcinoma of breast
- Ovarian cancer
- Mycosis fungoides
- Minimal Change Nephrotic Syndrome in Pediatric Patients
Therapeutic Effects of Endoxan N 1gm Injection
Endoxan N 1gm Injection slows or stops the growth of cancer cells by damaging the hereditary material (DNA and RNA) of the cancer cells. In nephrotic syndrome, it works by suppressing the body’s immune system.
Interaction of Endoxan N 1gm Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Endoxan NÂ 1gm Injection and cause potential side effects.Â
More Information about Endoxan N 1gm Injection
- Store the medication at a temperature between 2°C - 8°C to prevent possible sintering or the formation of lumps.
- Keep the medication protected from light to maintain its stability and effectiveness.
How to consume Endoxan N 1gm Injection
Dissolve the contents of the medication in 50 ml of Sterile Water for Injections IP and shake until fully dissolved. The solution should be used immediately after preparation. It is usually administered via the intravenous route. Do not self-administer.
Safety Advices for Endoxan N 1gm Injection
 Â
Pregnancy
 Â
Endoxan NÂ 1gm Injection can cause fetal harm when administered to a pregnant woman. Inform your physician if you are pregnant or planning to get pregnant before taking this medication. Your physician will instruct you to take it when it is necessary.
 Â
Breast Feeding
 ÂAvoid Endoxan N 1gm Injection if you are breastfeeding. Consult your doctor for potential risks and benefits.
 Â
Lungs
 Â
It is unknown whether Endoxan NÂ 1gm Injection can be given in lung failure patients. Inform your doctor if you have any lung diseases.Â
 Â
Liver
  Endoxan N 1gm Injection should be used with caution in patients with liver disease. Please consult your doctor.
 Â
Alcohol
 ÂIt is unsafe to consume alcohol with Endoxan N 1gm Injection. Please consult your doctor for more advice.
 Â
Driving
  It is not recommended while driving because it causes dizziness, and patients may lack concentration and alertness.
Side Effects of Endoxan N 1gm Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.Â
Serious
- Infections
- Immune suppression
- Blood disorders
- Allergic reactions
- Abnormal liver function
- Inflammation of the bladder
- Kidney diseases
- blood in urine
- sterility
- impaired wound healing
Common
- Nausea, vomiting
- Low white blood cell count
- Diarrhea
- Hair loss
- Fever
- Weakness
- Inflammation
- Dizziness
- Blurred vision
- amenorrhea
Word of Advice
Inform the doctor if the patient has any kidney, liver, or heart problems and medication taken for different medical conditions. It causes immune suppression and hence inform the doctor if there are any immune problems. Avoid this medication if the patient is pregnant or breastfeeding mother. The patient undergoing treatment with Endoxan NÂ 1gm Injection may have dizziness, and blurred vision. Consult your doctor before driving and handling heavy machines.
FAQs
Q 1. Can Endoxan N 1gm Injection cause infertility?
Yes, Endoxan N 1gm Injection can cause infertility in both men and women hence consult the doctor before taking this medication.
Q 2. Is Endoxan N 1gm Injection chemotherapy medication?
Yes, Endoxan N 1gm Injection is a chemotherapy medicine, and it works by killing cancer cells. It prevents the spreading of cancer cells to different parts.
Q 3. Can Endoxan N 1gm Injection cause weight loss?
Yes, Endoxan N 1gm Injection causes weight loss due to reduced appetite, and consult the doctor if there is excessive weight loss.
Q 4. Can Endoxan N 1gm Injection be used during pregnancy?
No, it is highly unsafe to use this medication during pregnancy as it can cause harmful effects on the developing baby.
Q 5. Can Endoxan N 1gm Injection cause hair loss?
Yes, Endoxan N 1gm Injection can cause hair loss, and consult the doctor if there is excessive hair loss.
Q 6. Can I take Endoxan N 1gm Injection while driving?
No, it is not recommended while driving because it makes patients dizzy, and patients may lack concentration and alertness.
Fact Box of Endoxan N 1gm Injection
| Molecule Name: Cyclophosphamide | Therapeutic Class: 1. Anti-cancer 2. Antirheumatic 3. Immunomodulators |
| Pharmacological Class: Alkylating agent | Indications: 1. Malignant lymphomas 2. Treat certain types of cancers such as eye, blood, breast, and ovarian cancer. 3. Minimal Change Nephrotic Syndrome in Pediatric Patients |
References
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.
- Baxter, Electronic medicines compendium (emc), [ Revised on June 2016] [ Accessed on 8th April 2021], https://www.medicines.org.uk/emc/product/1815/smp
- Baxter, US Food and Drug Administration, [ Revised on May 2013] [ Accessed on 7th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
