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ENDOXAN N 500MG INJECTION_1
ENDOXAN N 500MG INJECTION_2
ENDOXAN N 500MG INJECTION_1
10% Off

Endoxan N 500mg Injection

Prescription Required

cold-chain

Salt Composition : Cyclophosphamide

Manufacturer : ZYDUS CADILA

Origin of Medicine : India

MRP: ₹84
Price : ₹76
You Save : ₹8 (10%)

1 Vial(s)

Prepaid Only. Non-Returnable
Out of Stock
Pincode
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Introduction to Endoxan N 500mg Injection

Endoxan N 500mg Injection is a chemotherapy drug containing the active constituent cyclophosphamide. It is used to treat various malignancies (abnormal production of cells is called cancer, and if they spread to other organs, they are called malignancies). Endoxan N 500mg Injection can be used to treat malignant lymphomas (cancers that start from the lymphatic system of the body- vessels, fluid, and lymphoid tissue) such as Hodgkin’s disease, lymphocytic lymphoma, and mixed-cell type lymphoma. 

It is used to treat leukemias, neuroblastoma, ovarian cancer, retinoblastoma, and breast carcinoma. It can also treat Minimal Change Nephrotic syndrome in pediatric patients (kidney disease in which large quantities of protein are lost in urine). Endoxan N 500mg Injection is contraindicated in pregnancy, patients with acute infections, urinary tract infections, urinary outflow obstruction, and bone marrow disorders.  

Treatment with this medicine may lead to immune suppression, bone marrow failure, cardiotoxicity, renal toxicity, pulmonary toxicity, and secondary malignancies. Inform your doctor if you have pre-existing kidney disease, immune conditions, cardiac disorders, or liver diseases.

Uses of Endoxan N 500mg Injection

  • Malignant lymphomas
  • Leukemias
  • Retinoblastoma
  • Carcinoma of breast
  • Ovarian cancer
  • Mycosis fungoides
  • Minimal Change Nephrotic Syndrome in Pediatric Patients

Therapeutic Effects of Endoxan N 500mg Injection

Endoxan N 500mg Injection Injection slows or stops the growth of cancer cells by damaging the hereditary material (DNA and RNA) of the cancer cells. In nephrotic syndrome, it works by suppressing the body’s immune system.

Interaction of Endoxan N 500mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Endoxan N 500mg Injection and cause potential side effects. 

More Information about Endoxan N 500mg Injection

Keep out of sight and reach of children. Store vials below or at 25°C.

How to consume Endoxan N 500mg Injection

Endoxan N 500mg Injection will be administered intravenously by healthcare professionals experienced in cancer chemotherapy. Do not self-administer. 

Safety Advices for Endoxan N 500mg Injection

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Pregnancy

  

Endoxan N 500mg  Injection can cause fetal harm when administered to a pregnant woman. Inform your physician if you are pregnant or planning to get pregnant before taking this medication. Your physician will instruct you to take it when it is necessary.

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Breast Feeding

  

Avoid Endoxan N 500mg Injection if you are breastfeeding. Consult your doctor for potential risks and benefits.

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Lungs

  

It is unknown whether Endoxan N 500mg Injection can be given in lung failure patients. Inform your doctor if you have any lung diseases. 

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Liver

  

Endoxan N 500mg Injection should be used with caution in patients with liver disease. Please consult your doctor.

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Alcohol

  

It is unsafe to consume alcohol with Endoxan N 500mg Injection. Please consult your doctor for more advice.

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Driving

  

It is not recommended while driving because it causes dizziness, and patients may lack concentration and alertness.

Side Effects of Endoxan N 500mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. 

Serious

  • Infections
  • Immune suppression
  • Blood disorders
  • Allergic reactions
  • Abnormal liver function
  • Inflammation of the bladder
  • Kidney diseases
  • blood in urine
  • sterility
  • impaired wound healing

Common

  • Nausea, vomiting
  • Low white blood cell count
  • Diarrhea
  • Hair loss
  • Fever
  • Weakness
  • Inflammation
  • Dizziness
  • Blurred vision
  • amenorrhea

Word of Advice

Inform the doctor if the patient has any kidney, liver, or heart problems and medication taken for different medical conditions. It causes immune suppression and hence inform the doctor if there are any immune problems. Avoid this medication if the patient is pregnant or breastfeeding mother. The patient undergoing treatment with Endoxan N 500mg  Injection may have dizziness, and blurred vision. Consult your doctor before driving and handling heavy machines.

FAQs

Q 1. Can Endoxan N 500mg Injection cause infertility?

Yes, Endoxan N 500mg Injection can cause infertility in both men and women hence consult the doctor before taking this medication.

Q 2. Is Endoxan N 500mg Injection chemotherapy medication?

Yes, Endoxan N 500mg Injection is a chemotherapy medicine, and it works by killing cancer cells. It prevents the spreading of cancer cells to different parts.

Q 3. Can Endoxan N 500mg Injection cause weight loss?

Yes, Endoxan N 500mg Injection causes weight loss due to reduced appetite, and consult the doctor if there is excessive weight loss.

Q 4. Can Endoxan N 500mg Injection be used during pregnancy?

No, it is highly unsafe to use this medication during pregnancy as it can cause harmful effects on the developing baby.

Q 5. Can Endoxan N 500mg Injection cause hair loss?

Yes, Endoxan N 500mg Injection can cause hair loss, and consult the doctor if there is excessive hair loss.

Q 6. Can I take Endoxan N 500mg Injection while driving?

No, it is not recommended while driving because it makes patients dizzy, and patients may lack concentration and alertness.

Fact Box of Endoxan N 500mg Injection

Molecule Name: Cyclophosphamide 

Therapeutic Class:

1. Anti-cancer

2. Antirheumatic

3. Immunomodulators

Pharmacological Class: Alkylating agent

Indications: 

1.  Malignant lymphomas

2. Treat certain types of cancers such as eye, blood, breast, and ovarian cancer.

3. Minimal Change Nephrotic Syndrome in Pediatric Patients

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.
  2. Baxter, Electronic medicines compendium (emc), [ Revised on June 2016] [ Accessed on 8th April 2021], https://www.medicines.org.uk/emc/product/1815/smp
  3. Baxter, US Food and Drug Administration, [ Revised on May 2013] [ Accessed on 7th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.