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Gufistra 2mg Tablet
Prescription Required
Salt Composition : Estradiol
Manufacturer : GUFIC BIOSCIENCE LTD
Origin of Medicine : India
28 Tablet(s) In A Strip
Introduction to Gufistra 2mg Tablet
Gufistra 2mg Tablet contains an active ingredient called estradiol which belongs to a group of medicines called vaginal Hormone Replacement Therapy (HRT). It falls within the category of hormones known as estrogens and shares identical properties with the naturally occurring Gufistra 2mg Tablet is synthesised by women's ovaries. It is indicated to treat menopausal symptoms such as 'vaginal atrophy' (dryness or irritation of the vagina) in elderly women who have passed the stage of menopause.
It is not recommended to use Gufistra 2mg Tablet if you are allergic to the active compound estradiol and its constituents. It is not advised to use Gufistra 2mg Tablet if you have breast cancer or any type of cancer that is oestrogen receptor sensitive. It is not recommended to use Gufistra 2mg Tablet if you have a clotting disorder or blood clot in veins (lungs or legs) and unexplained vaginal bleeding.
It is not advised to consume Gufistra 2mg Tablet if you have a heart attack, stroke, angina or abnormal liver function tests. It is not given to patients with a rare inherited blood disorder called porphyria. The risk of gallbladder disease is elevated by estrogen intake. Stop using estrogen if you experience cholestatic jaundice, severe hypertriglyceridemia, severe hypercalcemia, or vision loss. It is advised to keep an eye on women receiving thyroid replacement treatment.
Inform your doctor if you have vaginal bleeding, heart, kidney, lung or liver problems, diabetes, asthma, high blood pressure, or hearing disorder. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding. Speak with your doctor about your medical history to the doctor. It is necessary to inform your healthcare provider about all the medicines you are taking, including herbal, vitamin, and over-the-counter medicines.
Uses of Gufistra 2mg Tablet
- Relieve menopausal symptoms of 'vaginal atrophy' (in the vagina such as dryness or irritation)
- Treatment for hypogonadism, castration, or primary ovarian failure-related hypoestrogenism
- Preventing osteoporosis after menopause
Therapeutic Effects of Gufistra 2mg Tablet
Gufistra 2mg Tablet primarily acts by binding to estrogen receptors (ERs) present on the surface of target cells upon binding to its receptor, Gufistra 2mg Tablet induces a conformational change in the receptor, leading to its activation. Gufistra 2mg Tablet replaces estrogen (female sex hormone) and prevents the symptoms of menopause, like vaginal irritation or dryness.
Interaction of Gufistra 2mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Gufistra 2mg Tablet and can cause undesirable side effects.
More Information about Gufistra 2mg Tablet
- Protect from moisture
- Store Gufistra 2mg Tablet at 25˚C
- Keep children away from the sight and reach of this medication.
How to consume Gufistra 2mg Tablet
Take Gufistra 2mg Tablet exactly as prescribed by your healthcare provider. Do not adjust the dosage or frequency without consulting your doctor. Take your Gufistra 2mg Tablet at the same time each day to maintain a consistent level of hormones in your body. Swallow the Gufistra 2mg Tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this may affect its effectiveness or increase the risk of side effects.
Safety Advices for Gufistra 2mg Tablet
Pregnancy
Gufistra 2mg Tablet is not recommended for pregnant women. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant.
Breast Feeding
It is unknown whether Gufistra 2mg Tablet is excreted in breast milk. Consult your doctor before using it. Seek your doctor for more information.
Lungs
Inform your physician about any underlying lung disorders before taking Gufistra 2mg Tablet, as this medication should be used cautiously in lung disease patients.
Liver
Inform your physician about any underlying liver disorders before taking Gufistra 2mg Tablet, as this medication should be used cautiously in liver disease patients.
Alcohol
It is unknown whether it is safe to consume alcohol under medication. So, it is recommended to consult your doctor before taking medicine.
Driving
It is unknown whether Gufistra 2mg Tablet alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Side Effects of Gufistra 2mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Common
- Headache
- Stomach pain
- Vaginal bleeding
- Discharge or discomfort.
Serious:
- Ovarian cancer
- Blood clots
- Heart attack
- Breast lumps
- Stroke
Word of Advice
It is recommended to examine your breast (mammogram) to avoid the risk of breast cancer caused by the drug and inform your doctor if you have any changes in skin colour. Don't apply it on your breast, eye, or other part of the body apart from the application site. Inform your doctor if you have uterus cancer or a history of blood clots. Regularly monitoring liver function tests, thyroid tests, bone mineral density, and blood pressure is advised as treatment with Gufistra 2mg Tablet can alter these values.
FAQs
Q 1. What are the precautions I need to take while taking Gufistra 2mg Tablet?
Inform your medical history to the doctor. It will be useful for him to treat you based on your health. Inform your doctor if you have kidney, liver, or heart disease, diabetes, gallbladder problems, or asthma before starting to use the medicine.
Q 2. Can I suddenly stop taking Gufistra 2mg Tablet?
Stopping your Gufistra 2mg Tablet treatment suddenly without first talking to your doctor is not advised. When estrogen medication is abruptly stopped, withdrawal symptoms and maybe rebound effects might occur. Talk to your healthcare practitioner about stopping or altering your therapy so that a safe and gradual plan may be created.
Q 3. Can I take Gufistra 2mg Tablet if I have a history of allergies to it?
Consult your doctor if you are allergic to Gufistra 2mg Tablet or any of the ingredients should be used before starting the medicine.
Q 4. What happens if a pregnant woman takes Gufistra 2mg Tablet?
Gufistra 2mg Tablet is not recommended for premenopausal women or pregnant women, as it may cause undesirable side effects if it is used during the period of pregnancy.
Q 5. Is there any possibility of having breast cancer when I use Gufistra 2mg Tablet?
Yes, Gufistra 2mg Tablet may cause breast cancer as a side effect. So, it is advised that you examine your breasts while under medication.
Fact Box of Gufistra 2mg Tablet
Molecule name: Estradiol
| Therapeutic class: Hormones |
Pharmacological class: Androgens | Indications: 1. Relieve menopausal symptoms of 'vaginal atrophy' (in the vagina such as dryness or irritation) 2. Treatment for hypogonadism, castration, or primary ovarian failure-related hypoestrogenism 3. Preventing osteoporosis after menopause |
Dosage form: Tablet | Habit forming: No
|
References
- Mercury Pharmaceuticals Limited, Electronics Medicines Compendium (EMC), [Revised on Jan 2024], [Accessed on 13th March 2024] , https://www.medicines.org.uk/emc/files/pil.11779.pdf
- Ther-Rx Corporation, US Food and Drug Administration,[Revised on April 2008], [Accessed on 13th March 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022014s001lbl.pdf
- Pfizer, [Revised on Feb 2024], [Accessed on 13th March 2024], https://labeling.pfizer.com/ShowLabeling.aspx?id=595
- Novartis Pharmaceuticals Corporation, [Revised on October 2021], [Accessed on 13th March 2024], https://www.novartis.com/us-en/sites/novartis_us/files/Vivelle_DOT.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Androgens and drugs for erectile dysfunction, 7th edition, 2013, 296-300.
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