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Halaven 0.5mg Injection
Prescription Required
Salt Composition : Eribulin
Manufacturer : EISAI PHARMACEUTICALS INDIA PVT LTD
Origin of Medicine : Japan
1 Vial(s) Of 2ml
EISAI PHARMACEUTICALS INDIA PVT LTD offers a Patient Assistance Program on Halaven 0.5mg Injection for its Indian patients to help reduce the cost of their medications. Eligibility for PAP may vary. Click ‘Know More About PAP’ to get a call from us!
Introduction to Halaven 0.5mg Injection
Halaven 0.5mg Injection is a chemotherapy drug that contains the active substance eribulin, which belongs to the class of antineoplastic agents. Halaven 0.5mg Injection is used in adults for advanced breast cancer or liposarcoma (a type of cancer originating from fat tissue) when other treatments have stopped working.
It is not recommended to take Halaven 0.5mg Injection if you are allergic to Eribulin or any of its other ingredients. Consult your doctor if you believe this applies to you. It is not recommended for children and adolescents younger than 18 years since the effects of Halaven 0.5mg Injection in this population are unknown. Before starting the treatment, you should inform your physician if you have fever, infections, liver, or heart problems. Before starting the treatment, give a detailed account of your medical history and medications.
Uses of Halaven 0.5mg Injection
- Advanced breast cancer
- Liposarcoma
Therapeutic Effects of Halaven 0.5mg Injection
Eribulin stops the growth and spread of cancer cells, specifically targeting the growth phase of microtubules, which are structures that help cells divide. It prevents them from growing without interfering with their shrinking phase. Additionally, it causes tubulin, a protein essential for cell division, to clump together in a way that disrupts cell division. This ultimately leads to the blockage of the cell cycle (G2/M phase), disrupting the formation of structures necessary for cell division (mitotic spindles) and triggering cell death through apoptosis.
Interaction of Halaven 0.5mg Injection with other drugs
Inform your doctor about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Halaven 0.5mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Halaven 0.5mg Injection
- Store Halaven 0.5mg Injection in the refrigerator between 25°C.
- Keep it in its original packaging.
- Protect it from light and moisture.
- Keep it out of the reach of children and pets.
How to consume Halaven 0.5mg Injection
Halaven 0.5mg Injection will be given to you by your healthcare provider. It is injected directly into a vein (intravenous infusion) in a cycle. Your healthcare provider determines the dose, duration, and frequency based on your age, body weight, and severity of your condition. If you forget or miss your Halaven 0.5mg Injection cycle dose, make another appointment as soon as possible. Do not wait until your next planned visit. Do not stop the treatment without physician advice.
Safety Advices for Halaven 0.5mg Injection
Pregnancy
Halaven 0.5mg Injection is unsafe for pregnant women as it may cause fetal harm. Inform your doctor promptly if you are pregnant, planning for pregnancy, or think you may get pregnant before starting the treatment with Halaven 0.5mg Injection.
Breast Feeding
Halaven 0.5mg Injection is not recommended while breastfeeding since it is unknown whether it passes through breast milk. Inform your doctor if you are breastfeeding or planning to breastfeed before starting the treatment with Halaven 0.5mg Injection.
Lungs
Halaven 0.5mg Injection can cause side effects like blood clots in the lungs and inflammation of the lungs. Inform your doctor if you have ever had lung disorders before starting the treatment, as its symptoms may worsen with Halaven 0.5mg Injection.
Liver
Halaven 0.5mg Injection can affect the liver's normal functioning, causing abnormalities in liver function tests. Hence, you should inform your healthcare provider if you have pre-existing liver problems before starting this treatment.
Alcohol
Halaven 0.5mg Injection contains small amounts of alcohol. Hence, it is generally recommended that patients taking Halaven 0.5mg Injection avoid or limit their alcohol intake, as alcohol can enhance the risk of liver damage and exacerbate any liver-related side effects of Halaven 0.5mg Injection.
Driving
Halaven 0.5mg Injection causes tiredness and dizziness, which may impair your ability to drive, cycle, or operate machinery. Avoid doing so until the treatment.
Side Effects of Halaven 0.5mg Injection
Side effects are unwanted symptoms that occur due to medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Sepsis (severe infection)
- Severe allergic reaction
- Serious skin conditions (Stevens-Johnson syndrome)
Common
- Decrease in the number of white blood cells or red blood cells
- Tiredness or weakness
- Nausea, vomiting, constipation, diarrhea
- Numbness, tingling or prickling sensations
- Fever
- Loss of appetite, weight loss
- Difficulty breathing, cough
- Pain in the joints, muscles, and back
- Headache
- Hair loss
Word of Advice
Your doctor will monitor your liver function via blood tests and assess your heart function before and during treatment. If you are a woman who could become pregnant, ensure reliable birth control while taking Halaven 0.5mg Injection and for at least three months after stopping it. Consult your doctor for guidance on alternative contraception methods to avoid pregnancy during this treatment. Talk to your oncologist if you need dental treatment. Always tell your dentist you are having cancer treatment. This treatment can affect fertility in men and women. If you are worried about this, it is important to talk with your doctor before you start treatment.
If you experience diarrhea while taking Halaven 0.5mg Injection, try to drink at least 2 liters of fluids daily and avoid alcohol, caffeine, milk products, and high-fat and high-fiber foods. If constipation occurs, increase your fluid intake, consume high-fiber foods, and engage in regular gentle exercise. Contact the hospital for advice; your doctor may prescribe laxatives to help constipation. If you notice a loss of appetite, don't worry if it lasts for a day or two, but if it persists or if you're losing weight, inform your nurse or dietitian for guidance. They may recommend supplements, dietary changes, or adjustments to eating habits to address these issues.
FAQs
Q 1. What is the most important information I should know while taking Halaven 0.5mg Injection?
Halaven 0.5mg Injection can cause serious adverse effects such as low white blood cell count, numbness, tingling, and pain in the hands and feet. Inform your physician immediately if you face any of these symptoms.
Q 2. Does Halaven 0.5mg Injection cause infertility?
Yes, Halaven 0.5mg Injection causes infertility in men and women. It is necessary to use effective birth control methods during the treatment and for three weeks (females) and 14 weeks (males) after the final dose of the injection.
Q 3. Is hair loss caused by Halaven 0.5mg Injection reversible?
Hair loss is a common side effect of Halaven 0.5mg Injection Injection. It is reversible, but it depends totally on the severity of the hair loss and varies from person to person. Consult your doctor if you have severe hair loss.
Q 4. Do I have to follow any special dietary requirements while taking Halaven 0.5mg Injection?
It depends upon the severity of the disease condition. You can have a normal diet until your physician tells you to follow any special food or diet chart. Check with your doctor if you have any nutrition concerns.
Q 5. What should I do if I miss taking Halaven 0.5mg Injection?
It is important to get the injection at the right time. If you missed your appointment, contact your healthcare provider and schedule your dosing immediately. Keep follow-ups on your next schedule.
Fact Box of Halaven 0.5mg Injection
Molecule name: Eribulin
| Therapeutic class: Anticancer |
Pharmacological class: Monoclonal antibody-drug conjugate | Indications: 1. Advanced breast cancer 2. Liposarcoma |
Dosage form: Injections | Habit forming: No
|
References
- Eisai Europe Limited, Electronic medicines compendium (EMC), [Revised on Jan 2023] [Accessed on Feb 2024], https://www.medicines.org.uk/emc/files/pil.4517.pdf
- Genentech, Inc, US Food and Drug Administration (FDA), [Revised on Jan 2016], [Accessed on Feb 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/201532s015lbl.pdf
- Goodman & Gilman's Pharmacological Basis of Therapeutics, Pharmacotherapy of neoplastic drugs, 13th edition, 2018, 1187.
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