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Honvan 120mg Tablet
Prescription Required
Salt Composition : Fosfestrol
Manufacturer : ZYDUS CADILA
Origin of Medicine : India
10 Tablet(s) In A Strip
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Introduction to Honvan 120mg Tablet
Honvan 120mg Tablet is a hormonal chemotherapy medication containing the active constituent Fosfestrol. It is a synthetic estrogen-like medication that has been used to treat certain types of advanced prostate and breast cancer. The Prostate is a gland surrounding the urethra just below the bladder. The prostate produces the seminal fluid which nourishes the sperm. In prostate cancer, patients experience trouble urinating, blood in urine and semen, bone pain, weight loss, and erectile dysfunction. Honvan 120mg Tablet can be a useful treatment option for men who are unable to undergo surgery or radiation therapy, or who have not responded well to other forms of chemotherapy.
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Honvan 120mg Tablet may also be used in combination with other medications or treatments to further improve outcomes for patients. Tell your doctor if you have a history of heart disorders, liver impairment, diabetes, or hypertension, before taking this medication. Do not skip or double the dose. Discontinue the medication if you experience any hypersensitive reactions. It is vital to tell your doctor if you have any blood clot disorders. Tell your doctor about all medications you are taking before the treatment.
Uses of Honvan 120mg Tablet
Honvan 120mg Tablet is indicated to treat the following conditions:Â
- Prostate cancer
- Breast cancer
Therapeutic Effects of Honvan 120mg Tablet
The therapeutic effect of Honvan 120mg Tablet is its ability to slow down the growth and spread of prostate cancer in men by blocking the effects of testosterone, which can stimulate the growth of prostate cancer cells. By doing so, this medication can help to shrink tumors, relieve symptoms such as pain and difficulty urinating, and improve the overall quality of life for men with advanced prostate cancer.
Interaction of Honvan 120mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Honvan 120mg Tablet and reduce effectiveness by causing undesirable side effects.
More Information about Honvan 120mg Tablet
- Honvan 120mg Tablet should be stored at room temperature, between 20°C to 25°C (68°F to 77°F).
- Protected from light.
- Keep it in its original packaging until it is ready to be used.
- Keep out of the reach of children and pets.
- Should be disposed of properly.
How to consume Honvan 120mg Tablet
Honvan 120mg Tablet is an oral medication usually taken once a day, at approximately the same time each day, with or without food. It should be taken as prescribed by a doctor or other healthcare provider. These capsules should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect the way the medication is absorbed and decrease its effectiveness. You should not take a double dose to make up for the second dose.
Safety Advices for Honvan 120mg Tablet
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Pregnancy
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Honvan 120mg Tablet is unsafe during pregnancy as it can cause fetal harm. It is recommended to avoid this medication during pregnancy.
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Breast Feeding
 ÂHonvan 120mg Tablet can excrete in human milk and cause potential harm to a nursing infant. So it is not safe during pregnancy.
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Lungs
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Safety and efficacy are not well known for lungs while using Honvan 120mg Tablet. So patients should consult their healthcare provider if they have any concerns or any pre-existing lung disease.
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Liver
  Honvan 120mg Tablet is primarily metabolized in the liver, so inform your healthcare provider if you have any liver problems or diseases. This medication may also increase liver enzymes, which can be a sign of liver damage or inflammation. Patients taking this medication require regular blood tests to monitor liver function.
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Alcohol
 ÂIt is recommended to avoid consuming alcohol while taking Honvan 120mg Tablet, as alcohol can increase the risk of certain side effects associated with the medication, such as stomach ulcers or gastrointestinal bleeding.
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Driving
  Patients receiving Honvan 120mg Tablet should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
Side Effects of Honvan 120mg Tablet
Like all medications, Honvan 120mg Tablet can cause side effects, although not everyone who takes it will experience them.Â
Serious:
- Blood clots
- Stroke
- Allergic reactions
- Liver damage
- Changes in vision
- Seizures or convulsions
- Increase the risk of osteoporosis
Common:
- Hot flashes
- Impotence (inability to achieve or maintain an erection)
- Decreased libido (sex drive)
- Nausea and vomiting
- Diarrhea or constipation
- Headache
- Dizziness
- Weakness or fatigue
- Injection site reactions (such as pain, redness, or swelling)
- Fluid retention and swelling in the legs and feet.
Word of Advice
If you are receiving treatment with Honvan 120mg Tablet, report any side effects or concerns promptly. To reduce your risk of falls and fractures, you should take steps such as using assistive devices, wearing appropriate footwear, and participating in regular physical activity as recommended by your healthcare provider. If you are pregnant or planning to become pregnant, or if you are breastfeeding, it is important to discuss the risks and benefits with your healthcare provider. Reproductive-age women should use effective birth control during the treatment and for at least two weeks after their last dose. Making lifestyle changes, such as quitting smoking, maintaining a healthy weight, and eating a healthy diet, can also help support your overall health and reduce the risk of complications associated with cancer.
FAQs
Q 1. Can Honvan 120mg Tablet be used in children?
No, Honvan 120mg Tablet has not been studied in pediatric populations and is not approved for use in children.
Q 2. Can Honvan 120mg Tablet cause weight gain?
Weight gain is not a commonly reported side effect of Honvan 120mg Tablet. However, if you experience unexplained weight gain or swelling, you should consult your healthcare provider.
Q 3. Can Honvan 120mg Tablet cause changes in hair growth?
Hair loss or changes in hair growth are not commonly reported side effects of Honvan 120mg Tablet. However, if you experience hair loss or changes in hair growth, you should discuss this with your healthcare provider.
Q 4. Can Honvan 120mg Tablet affect fertility?
Honvan 120mg Tablet may cause temporary or permanent infertility in some patients, particularly in men receiving high doses. If you are concerned about fertility, you should discuss this with your healthcare provider.
Q 5. Can Honvan 120mg Tablet be used in patients with kidney disease?
Honvan 120mg Tablet should be used with caution in patients with kidney disease as it is eliminated from the body primarily through the kidneys. Your healthcare provider may need to adjust your Honvan 120mg Tablet dose or monitor your kidney function more closely if you have pre-existing kidney disease.
Q 6. Can Honvan 120mg Tablet be used in patients with heart disease?
Honvan 120mg Tablet should be used with caution in patients with heart disease as it may increase the risk of blood clots or cardiovascular events. Your healthcare provider may need to monitor your heart function more closely if you have pre-existing heart disease.
Q 7. Can I take Honvan 120mg Tablet if I am diabetic?
Honvan 120mg Tablet should be used with caution in diabetic patients. It can increase the risk of high blood sugar levels. Therefore, regular monitoring of blood sugar levels in diabetic patients.
Fact Box of Honvan 120mg Tablet
Molecule name: Fosfestrol  | Therapeutic class: Antineoplastic |
Pharmacological class: Non-selective estrogen receptor agonist
| Indications: Â 1. Prostate cancer 2. Breast cancer |
References
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 872.
- Chabner, B. A., & Longo, Cancer Chemotherapy and Biotherapy: Principles and Practice, 6 edition, 2019, 700-701.
- Kaye, S. B., Kerr, D. J., & Tait, D, Textbook of Medical Oncology, 4th edition, 2015, 305-306.
- DeVita, V. T., Lawrence, T. S., & Rosenberg: Principles & Practice of Oncology, 10th edition, 2015, 922-923.
- Mauro Orlando et al; Low-dose continuous oral Honvan 120mg Tablet is highly active in 'hormone-refractory' prostate cancer; Annals of Oncology; [Published on March 2000]; [Accessed on 22 April 2023], https://www.researchgate.net/publication/12554273_Low-dose_continuous_oral_Fosfestrol_is_highly_active_in_'hormone-refractory'_prostate_cancer
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