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I-Dox 20mg Injection
Prescription Required
Salt Composition : Pegylated Liposomal Doxorubicin
Manufacturer : GETWELL ONCOLOGY PVT LTD
Origin of Medicine : India
1 Vial(s) Of 10ml
Introduction to I-dox 20mg Injection
I-Dox 20mg Injection is an anticancer medication that contains the active constituent doxorubicin encapsulated in a closed lipid sphere (liposome). Cancer is a disease in which cells multiply in an uncontrolled and abnormal manner. This medication treats breast cancer, ovarian cancer, multiple myeloma (cancer of white blood cells called plasma cells), and AIDS-related Kaposi’s sarcoma. Â
People with HIV infection have the highest risk of Kaposi’s sarcoma (cancer that forms in the lining of the lymph and blood vessels). I-Dox 20mg Injection may be given alone or in combination with other anticancer medicines. This medication is not recommended for adolescents and children.Â
Use effective birth control during the treatment and at least six months after the last dose. It is important to tell your doctor if you are allergic to peanuts or soya if you are receiving medicines for heart or liver disorders, has diabetes, Kaposi’s sarcoma, or have oral problems before taking I-Dox 20mg Injection.
Uses of I-dox 20mg Injection
- Breast cancer
- Ovarian cancer
- Multiple myeloma
- AIDS-related Kaposi’s sarcoma
Therapeutic Effects of I-dox 20mg Injection
Doxorubicin inhibits the activity of the enzyme topoisomerase II, which is involved in the DNA (genetic material) multiplication of cancer cells. This prevents the growth and multiplication of cancer cells.Â
The unique formulation process of I-Dox 20mg Injection increases the time this medicine is circulating in the blood. It also helps deliver drugs from blood to the cancerous tissue rather than the healthy tissue.
Interaction of I-dox 20mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutrition or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with I-Dox 20mg Injection and can cause undesirable side effects.Â
More Information about I-dox 20mg Injection
- Keep I-Dox 20mg Injection out of sight and reach of children.
- Store refrigerated at 2°C - 8°C. Do not freeze.
How to consume I-dox 20mg Injection
Your dose and frequency of administration will be decided by your physician based on your disease condition and other factors. It will be given to you by a healthcare professional. Do not self-administer.Â
Safety Advices for I-dox 20mg Injection
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Pregnancy
 ÂI-Dox 20mg Injection may harm the unborn baby. You need to tell your physician if you are pregnant or planning to get pregnant before taking this medicine.Â
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Breast Feeding
 ÂStop breastfeeding before starting treatment with I-Dox 20mg Injection. You need to tell your physician if you are breastfeeding before taking this medicine.Â
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Lungs
 ÂIt is unknown whether I-Dox 20mg Injection can be given to patients with lung diseases. Please consult your physician if you have any lung problems.Â
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Liver
 ÂYou need to tell your physician if you have any liver disorders before taking I-Dox 20mg Injection.
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Alcohol
 ÂIt is not known whether it is safe to consume alcohol with I-Dox 20mg Injection. Please consult your doctor.
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Driving
 ÂI-Dox 20mg Injection may cause tiredness or sleepiness. Avoid driving if you are unwell. Please consult your doctor for more advice.Â
Side Effects of I-dox 20mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.Â
Serious:
- Fever, tiredness, bruising or bleeding
- Severe diarrhea, sores in mouth, nausea, vomiting
- Lung infections, shortness of breath
- Severe stomach pain
- Severe weaknessÂ
Common:
- Low blood cell counts
- Hair loss
- Decreased appetite
- Skin rashes
- Pain in the muscles and joints
- Constipation
- Feeling confused, difficulty sleeping
- Headache, dizziness, sleepiness
- Change in taste
- High or low blood pressure
- Excessive sweating
- Pain when passing urine
- Weight loss
- Muscle spasms
- Fast heartbeat
Word of Advice
Inform the doctor if the patient has allergic reactions, diabetes, blood pressure, kidney, liver diseases before taking this medication. Blood glucose levels, blood pressure, liver and kidney function should be monitored regularly while taking this medication. Don't stop this medication without the proper advice of the doctor. Avoid making plans for pregnancy or during pregnancy as this medication can cause harmful effects on the developing baby. Avoid driving after taking this medication because it causes dizziness and lack of concentration.
FAQs
Q 1. What is the use of I-Dox 20mg Injection?
This medication is used to treat breast cancer, ovarian cancer, multiple myeloma (cancer of white blood cells called plasma cells) and AIDS-related Kaposi’s sarcoma.
Q 2. Is it safe to use I-Dox 20mg Injection while driving ?
No, it is unsafe to use this medication while driving and handling heavy machineries as it causes lack of concentration and alertness.
Q 3. How does I-Dox 20mg Injection work?
It damages the genetic material (DNA) of the cancer cells and stops their growth and multiplication
Q 4. What are the side effects of I-Dox 20mg Injection?
The common side effects of these medications are nausea, vomiting, rash, weakness, low blood platelets, Fatigue, Fever, Loss of appetite, Anemia, and Constipation.
Q 5. Is it safe to use I-Dox 20mg Injection during pregnancy?
It is unsafe to use this medication in patients planning for pregnancy or during pregnancy and breastfeeding mothers as it causes harmful effects for the baby.
Fact Box of I-dox 20mg Injection
Molecule Name: Liposomal Doxorubicin | Therapeutic effects: Antineoplastics |
Pharmacological class: Anthracyclines | Indications: 1. Breast cancer 2. Ovarian cancer 3. Multiple myeloma 4. AIDS-related Kaposi’s sarcoma |
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1714.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 867.
- Baxter Holding BV, European medicines agency (ema), [Revised on May 2006] [ Accessed on 4th Dec 2021], https://www.ema.europa.eu/en/documents/product-information/caelyx-pegylated-liposomal-epar-product-information_en.pdf
- Ben Venue Laboratories, Inc, US Food and Drug Administration, [Revised on May 2007] [ Accessed on 4th Dec 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/050718s029lbl.pdfÂ
Disclaimer
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