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Imbruvica 140mg Capsule 90's
Prescription Required
Salt Composition : Ibrutinib
Manufacturer : JOHNSON & JOHNSON PVT LTD
Origin of Medicine : United States of America
90 Capsule(s) In A Bottle
PAP Information : Buy 1, get 1 Free. Contact us for latest updates.
Program Overview: JOHNSON & JOHNSON PVT Limited, is dedicated to helping patients in need of Imbruvica 140mg capsule. The program aims to provide eligible patients with access to the medication at a more affordable cost.
Program Benefits: This program covers two conditions, CLL (Chronic Lymphoid Leukemia) and NCL. Purchase one bottle of Imbruvica 140mg capsule, and you will receive 1 free additional bottle of Imbruvica 140mg capsule. Therefore, if eligible, you will have to pay only Rs. 3,65,759 for two bottles, which is Rs. 1,82,880 per bottle.
With MrMed's MRP discount of Rs. 70,241 per bottle and Johnson & Johnson’s PAP program, the overall savings is over Rs. 5.6 lakhs per purchase.
Eligibility Criteria: To qualify for Johnson & Johnson’s Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for Ibrutinib 140mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.
Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].
Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by Johnson & Johnson can avail of it without having to purchase the medication from MrMed.
Patient Assistance Programs
Program Overview: JOHNSON & JOHNSON PVT Limited, is dedicated to helping patients in need of Imbruvica 140mg capsule. The program aims to provide eligible patients with access to the medication at a more affordable cost.
Program Benefits: This program covers two conditions, CLL (Chronic Lymphoid Leukemia) and NCL. Purchase one bottle of Imbruvica 140mg capsule, and you will receive 1 free additional bottle of Imbruvica 140mg capsule. Therefore, if eligible, you will have to pay only Rs. 3,65,759 for two bottles, which is Rs. 1,82,880 per bottle.
With MrMed's MRP discount of Rs. 70,241 per bottle and Johnson & Johnson’s PAP program, the overall savings is over Rs. 5.6 lakhs per purchase.
Eligibility Criteria: To qualify for Johnson & Johnson’s Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for Ibrutinib 140mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.
Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].
Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by Johnson & Johnson can avail of it without having to purchase the medication from MrMed.
Introduction to Imbruvica 140mg Capsule 90's
Imbruvica 140mg capsule consists of the active ingredient Ibrutinib. It is indicated to treat blood cancers such as mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (CLL), Waldenstrom’s macroglobulinemia, and Marginal zone lymphoma (MZL). These are cancers of the white blood cells called lymphocytes that are part of the immune system. They differ from each other by the location where the cancer occurs, the type of lymphocytes affected, and certain other factors.
Imbruvica 140mg capsule is also used to treat chronic graft versus host disease (cGVHD) after the failure of systemic therapy. During allogeneic stem cell transplantation, the patient receives stem cells from the donor. GVHD occurs when donor cells view the patient’s cells as foreign and attack them. Before taking Imbruvica 140mg Capsule, you need to talk with your physician if you have bleeding problems, infection, liver problems, heart problems, or intolerance to some sugars. This medication is not recommended for adolescents and children.
It is vital to let the physician know if you have recently had or are about to have any surgical procedure. Your physician may stop the Imbruvica 140mg capsule for any planned surgical or medical procedure. Use effective birth control during the treatment and for at least one month after the final dose. Avoid having grapefruit or oranges in any form during this treatment; they may raise the amount of drug in the blood. Drink plenty of fluid to prevent dehydration. Inform your physician if you have diarrhea that does not go away.
Uses of Imbruvica 140mg Capsule 90's
Imbruvica 140mg capsule is used in the treatment of:
- Mantle cell lymphoma
- Chronic lymphocytic leukemia (Blood cancer)
- Small lymphocytic lymphoma
- Waldenstrom’s macroglobulinemia
- Chronic graft vs. host disease after failure of systemic therapy
Therapeutic Effects of Imbruvica 140mg Capsule 90's
The mechanism of action of Imbruvica 140mg Capsule involves blocking a specific protein called Bruton's tyrosine kinase (BTK), which plays a key role in the survival and growth of cancer cells. By inhibiting BTK, Imbruvica 140mg Capsule prevents the cancer cells from receiving the signals they need to grow and divide, leading to their eventual death.
Interaction of Imbruvica 140mg Capsule 90's with other drugs
Inform your healthcare professional about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications that interact with Imbruvica 140mg Capsule may reduce its effectiveness by causing undesirable side effects.
More Information about Imbruvica 140mg Capsule 90's
- Store the capsules in the original packaging at room temperature (20-25°C).
How to consume Imbruvica 140mg Capsule 90's
Consume this medicine at the same time each day. While taking Imbruvica 140mg Capsule, do not consume grapefruit or orange in any form during the treatment. Drink plenty of fluid to prevent dehydration.
Safety Advices for Imbruvica 140mg Capsule 90's
Pregnancy
This medicine can harm the unborn baby. Do not take Ibrutinib 140mg Capsule unless your physician instructs you to take it. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.
Breast Feeding
Do not breastfeed while you are under Imbruvica 140mg capsule and for at least one week after the last dose. Consult your physician for risks and benefits.
Lungs
Imbruvica 140mg capsule may cause interstitial lung disease. So if you have any respiratory disorder, inform your doctor before starting the treatment.
Liver
Inform your physician before starting this treatment if you have liver problems, including hepatitis B infection. Imbruvica 140mg capsule could cause the reactivation of the hepatitis B virus, which makes the condition fatal.
Alcohol
It is unknown whether it is safe to consume alcohol with the Imbruvica 140mg capsule. Please consult your doctor.
Driving
Imbruvica 140mg capsule may cause dizziness or tiredness. Avoid driving or operating machines if you feel dizzy or tired.
Side Effects of Imbruvica 140mg Capsule 90's
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Bleeding problems
- Infections
- Decrease in blood cell counts
- Heart problems
- High BP
- Secondary cancer
- Tumor lysis syndrome
- Severe allergic reactions
Common:
- Nausea, vomiting, diarrhea
- Tiredness
- Muscle and bone pain
- Rash and bruising
- Mouth sores
- Pneumonia
- Fever, chills
- Breathlessness
- Constipation
- Dizziness
- Body pain
- Swollen ankles and feet
- Increased creatinine levels in the blood
- Heavier periods and blood in urine
- Blurred vision
- Weakness and numbness
Word of Advice
Contact your doctor immediately if you experience bleeding, infection, shortness of breath, or chest discomfort. Report to your doctor if you have had a history of heart failure or hepatitis infection. It is not recommended to take this medicine before or after surgery as it causes a delay in wound healing. Discuss effective contraceptive options with your healthcare provider and use them during treatment and for a month after the last dose of Imbruvica 140mg capsule.
FAQs
Q 1. Can I take Imbruvica 140mg Capsule to prevent getting cancer in the future?
Imbruvica 140mg Capsule is not approved for use as a cancer prevention medication, and its long-term effects on healthy individuals are not fully understood. If you are concerned about your risk of developing cancer, you should speak with your doctor about appropriate cancer screening and prevention strategies.
Q 2. Can Imbruvica 140mg Capsule be taken with other medications?
Imbruvica 140mg Capsule can interact with other medications, so it is important to inform your doctor of all medications you are taking, including prescription, over-the-counter, and herbal supplements.
Q 3. How long do I need to take Imbruvica 140mg Capsule?
The length of treatment with Imbruvica 140mg Capsule will depend on your specific condition and response to the medication. Your doctor will monitor your progress and determine the duration of treatment.
Q 4. Can I drink alcohol while taking Imbruvica 140mg Capsule?
Alcohol consumption should be avoided while taking Imbruvica 140mg Capsule, as it may increase the risk of certain side effects, such as liver damage. You should talk to your doctor about any concerns you have regarding alcohol use.
Q 5. Can Imbruvica 140mg Capsule cure all types of cancer?
Imbruvica 140mg Capsule has been shown to be effective in treating certain types of blood cancers, but its efficacy in other types of cancer is still being studied. It is important to remember that cancer is a complex disease with many different causes and factors, and there is no single cure that works for all types of cancer. If you have been diagnosed with cancer, it is important to work with your doctor to determine the best treatment options for your specific case.
Q 6. Should I use contraception while under this Imbruvica 140mg capsule?
Yes, It is necessary to use contraception during and even after the last dose of the Ibrutinb 140mg capsule. Inform your doctor if you are pregnant or think you might be or if you are planning to get pregnant.
Fact Box of Imbruvica 140mg Capsule 90's
Molecule name: Ibrutinib
| Therapeutic class: Anti Neoplastics |
Pharmacological class: Bruton's tyrosine kinase (BTK) inhibitors | Indications: 1. Chronic lymphocytic leukemia (Blood cancer) 2. Small lymphocytic lymphoma 3. Waldenstrom’s macroglobulinemia 4. Chronic graft vs. host disease after failure of systemic therapy 5. Mantle cell lymphoma |
References
- Janssen-Cilag International Ltd, Electronic Medicines Compendium (EMC), [Revised on Dec 2021] [Accessed on 18th March 2023], https://www.medicines.org.uk/emc/files/pil.10040.pdf
- Janssen Biotech, Inc, US Food and Drug Administration, [Revised on May 2022] [ 18th March 2023], https://www.imbruvica.com/files/prescribing-information.pdf
- H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
- Sapna Parmar, Khilna Patel, Javier Pinilla-Ibarz, Ibrutinib (Imbruvica): A Novel Targeted Therapy for Chronic Lymphocytic Leukemia, Drug Forecast, Published on July 2014; Accessed on 18th March 2023]; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103574/pdf/ptj3907483.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
