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Kenadion 1mg Injection
Prescription Required
Salt Composition : Phytomenadione
Manufacturer : SAMARTH LIFE SCIENCES PVT LTD
Origin of Medicine : India
1 Ampoule(s) Of 0.5ml
Introduction to Kenadion 1mg Injection
Kenadion 1mg injection contains an active component as Kenadion 1mg injection. It plays an important role in blood clotting and bone health. It also helps in the synthesis of various clotting factors in the liver. This medication is often used in emergencies to reverse the effects of anticoagulant medications like warfarin. This medication is given to newborn infants who are at risk of bleeding disorders due to their low vitamin K levels at birth. It can be used to treat and prevent coumarin-induced skin necrosis. This medication is believed to play a role in bone health by supporting the synthesis of proteins involved in bone mineralization. It is used in individuals with certain malabsorption disorders, such as celiac disease, cystic fibrosis, and certain bile duct disorders. Celiac disease is an autoimmune disorder affecting the digestive system's response to gluten. Cystic fibrosis is a genetic condition causing mucus buildup in the lungs and digestive tract.
Individuals with known hypersensitivity or allergy to Kenadion 1mg injection or any of its components should avoid its use. It is involved in blood clotting, and its use might be cautioned in individuals with certain hypercoagulable states. It might interact with certain blood disorders or diseases, and its use should be discussed with a healthcare provider to determine its safety. Do not take this medication in cases of current blood clots (thrombosis). In rare cases, excessive use of this can interfere with red blood cell function and can cause hemolytic anemia. Always consult your healthcare provider before taking this medication. For older adults, it is essential to use Kenadion 1mg injection under the guidance of a qualified healthcare provider.Ā
Uses of Kenadion 1mg Injection
Kenadion 1mg injection is used in the following:
- Blood clotting regulation
- Warfarin reversal
- Newborns and hemorrhagic disease
- Malabsorption disorders
- Liver disease and clotting abnormalities
- Bone health and osteoporosis
- Gastrointestinal bleeding
- Coumarin-induced skin necrosis
Therapeutic Effects of Kenadion 1mg Injection
Kenadion 1mg injection operates through its vital role as a cofactor for the enzyme gamma-glutamyl carboxylase, which is responsible for adding carboxyl groups to specific amino acid residues in vitamin K-dependent proteins. This carboxylation process is essential for activating clotting factors such as prothrombin, VII, IX, and X, enabling them to participate in the coagulation cascade. These activated clotting factors, in turn, contribute to the formation of stable blood clots in response to injuries, preventing excessive bleeding and ensuring proper hemostasis.
Interaction of Kenadion 1mg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Kenadion 1mg injection, reducing effectiveness by causing undesirable side effects.Ā
More Information about Kenadion 1mg Injection
- Store at room temperature, around 20-25Ā°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Kenadion 1mg Injection
Kenadion 1mg injection administered as intravenous injection, by healthcare provider. The specific route chosen depends on the patient's condition, urgency of treatment, and healthcare provider's recommendation.Ā
Safety Advices for Kenadion 1mg Injection
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Pregnancy
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If you are pregnant or planning for pregnancy, it is important to consult a healthcare provider before using Kenadion 1mg injection.
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Breast Feeding
Ā ĀIf you are breastfeeding women, it is important to consult a healthcare provider before starting Kenadion 1mg injection.
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Lungs
Ā Ā For individuals with liver conditions, such as liver disease or impairment, it is important to consult your healthcare provider before using Kenadion 1mg injection.Ā
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Liver
Ā Ā If you have lung conditions, discussing Kenadion 1mg injection with a healthcare provider is advisable.
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Alcohol
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It is recommended to avoid excessive alcohol consumption and considered unsafe, as it can potentially interfere with the effectiveness of the Kenadion 1mg injection.
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Driving
Ā Ā If you experience any side effects like dizziness, confusion, or drowsiness while taking the medication, you should take Kenadion 1mg injection.
Side Effects of Kenadion 1mg Injection
Kenadion 1mg injection causes some side effects like all medications, although not everyone will experience them.Ā
Serious
- Allergic reactions
- Unusual bleeding or bruising
Common
- Injection site discomfort
- Mild gastrointestinal symptoms
Word of Advice
Inform your healthcare provider of allergies, medical history, and medication use before starting Kenadion 1mg injection. Discuss potential allergic reactions, unusual bleeding, or bruising. Pregnant or breastfeeding individuals should seek medical advice. Caution is advised for those with liver or lung conditions, and any interactions with alcohol should be discussed. Dosage, particularly for children and older adults, should be followed as directed by the healthcare professional. Before surgeries or dental procedures, inform professionals about your medication use. Regular monitoring and communication with healthcare providers are important for those taking anticoagulants. Avoid discontinuation without professional guidance. While sunlight exposure is not directly affected, sun protection remains important. Ultimately, consult your healthcare provider for personalized advice, ensuring safe and effective usage of this medication.
FAQs
Q 1. How long does it take for Kenadion 1mg injection to work?
The onset of action varies based on the route of administration and the specific medical condition. Intravenous administration typically works faster than oral or intramuscular administration.
Q 2. Can Kenadion 1mg injection cause vitamin K toxicity?
Kenadion 1mg injection is generally safe when used as directed. However, excessive use over a prolonged period could potentially lead to vitamin K toxicity. Always follow healthcare provider recommendations.
Q 3. Is Kenadion 1mg injection used for cosmetic purposes?
Kenadion 1mg injection has been explored for cosmetic use to reduce the appearance of dark circles under the eyes. However, such uses are not established and should be discussed with a healthcare provider.
Q 4. Can I take Kenadion 1mg injection with other vitamins?
Kenadion 1mg injection is a specific form of vitamin Kā. While it can be taken alongside other vitamins, informing your healthcare provider about your complete supplement regimen is essential.
Q 5. Can I adjust my Kenadion 1mg injection dosage on my own?
No, do not adjust the dosage of Kenadion 1mg injection without consulting your healthcare provider. Changes in dosage should be made under professional guidance.
Q 6. Should Kenadion 1mg injection be discontinued abruptly?
No, you should not discontinue Kenadion 1mg injection without consulting your healthcare provider. Abrupt discontinuation could affect blood clotting function.
Fact Box of Kenadion 1mg Injection
Molecule name: Phytomenadione | Therapeutic class:Ā Hemostatic Agent |
Pharmacological class:Ā Fat-Soluble Vitamin | Indications:Ā 1. Blood clotting regulation 2. Warfarin reversal 3. Newborns and hemorrhagic disease 4. Malabsorption disorders 5. Liver disease and clotting abnormalities 6. Bone health and osteoporosis 7. Gastrointestinal bleeding 8. Coumarin-induced skin necrosis |
References
- Neon Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on 16 Feb 2022] [Accessed on 19th August 2023],Ā https://www.medicines.org.uk/emc/product/9755/smpc#gref
- Valdepharm, US Food, and Drug Administration, [Revised on May 2018] [Accessed on 19th August 2023],Ā https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/012223s042lbl.pdf
- P. Hanlon, M. Byers, J.P.H. Wilding and H.M. Macdonald, Environmental and nutritional factors in disease, Davidsonās Principles and Practice of Medicine, 22nd Edition, 2014, 97-132.
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