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Lapenem 300mg Injection
Prescription Required
Salt Composition : Biapenem
Manufacturer : LA RENON HEALTHCARE PVT LTD
Origin of Medicine : India
1 Vial(s)
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Introduction to Lapenem 300mg Injection
Lapenem 300mg Injection contains the active component Biapenem. It is a broad-spectrum antibiotic that belongs to the carbapenem class of drugs. Carbapenems are highly effective against a wide range of bacteria, including both Gram-positive and Gram-negative bacteria. They are often used as a last resort when other antibiotics fail or when multidrug-resistant bacteria cause the infection. Due to its potent activity against a broad range of bacteria, Lapenem 300mg Injection can be used to treat severe infections, such as complicated intra-abdominal infections, pneumonia, urinary tract infections, and septicemia.Â
While individual responses to medications can vary, most patients generally well-tolerated this medication. Common side effects may include gastrointestinal disturbances, skin rash, and headache. If you have a known hypersensitivity or allergic reaction to Lapenem 300mg Injection, other carbapenems, or any component of the medication, it would be contraindicated to use this medication. Caution is needed when this medication is administered to individuals with a history of seizures or epilepsy. is eliminated primarily through the kidneys. If you have severe renal impairment or end-stage renal disease, the Lapenem 300mg Injection dose may need to be adjusted or alternative treatment options considered.
Uses of Lapenem 300mg Injection
- Complicated intra-abdominal infections
- Pneumonia
- Urinary tract infections (UTIs)
- Septicemia
- Skin and soft tissue infections
- Bone and joint infections
- Meningitis
- Hospital-acquired infections
Therapeutic Effects of Lapenem 300mg Injection
Lapenem 300mg Injection exerts a therapeutic effect by inhibiting the growth and spread of bacterial infections. As a broad-spectrum carbapenem antibiotic, it demonstrates potent activity against many Gram-positive and Gram-negative bacteria. By binding to specific bacterial enzymes called penicillin-binding proteins (PBPs), this medication disrupts the synthesis of the bacterial cell wall, leading to cell lysis and death. Its broad coverage makes it effective against various multidrug-resistant bacteria, offering a valuable treatment option in severe or complicated infections.
Interaction of Lapenem 300mg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Lapenem 300mg Injection, reducing effectiveness by causing undesirable side effects.
More Information about Lapenem 300mg Injection
- Stored at controlled room temperature, between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Lapenem 300mg Injection
Lapenem 300mg Injection is typically administered through injection by a healthcare professional. The dosage and duration of treatment depend on the specific infection being treated, the severity of the infection, and individual patient factors such as age and overall health.
Safety Advices for Lapenem 300mg Injection
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Pregnancy
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The use of Lapenem 300mg Injection during pregnancy should be discussed with the healthcare provider. They will consider the specific circumstances, the patient's medical history, and individual factors to make an informed decision.
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Breast Feeding
 ÂLimited information regarding the safety of Lapenem 300mg Injection during breastfeeding is available. Breastfeeding individuals who require treatment should consult with their healthcare provider.Â
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Lungs
  Suppose you have a pre-existing lung condition or are concerned about the safety of the Lapenem 300mg Injection in your lungs. Consulting with your healthcare provider for personalized advice is recommended in that case.
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Liver
  Before starting Lapenem 300mg Injection, it is important to inform your healthcare provider about any existing liver conditions or impairments.
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Alcohol
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Alcohol consumption may increase the risk of certain side effects associated with Lapenem 300mg Injection, such as dizziness or stomach irritation.
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Driving
  Lapenem 300mg Injection may cause dizziness or drowsiness in some individuals. If you experience these side effects, avoiding activities requiring mental alertness, such as driving or operating machinery, is important.
Side Effects of Lapenem 300mg Injection
Lapenem 300mg Injection cause some side effects like all medications, although not everyone will experience them.Â
Serious:
- Gastrointestinal disturbances (nausea, vomiting, diarrhea)
- Skin reactions (rashes, itching, hives)
- Headache
- Injection site reactions (pain, swelling, redness)
Common:
- Allergic reactions (anaphylaxis)
- Central nervous system effects (seizures, encephalopathy)
- Changes in liver function
Word of Advice
Regarding your health and medication usage, it is important to prioritize open communication with your healthcare provider. Make sure to provide them with a comprehensive overview of your medical history, including any existing conditions, medications you are currently taking, or any allergies you may have. Elderly individuals may be more sensitive to the effects of Lapenem 300mg Injection. Monitor if you see any infusion-related problems. Age-related changes in metabolism reduce cardiac reserve, and other factors can increase the risk of adverse reactions. Close monitoring and appropriate dose adjustments are necessary for the elderly. Individuals with liver or kidney impairment should be closely monitored during treatment. Pregnant and breastfeeding women should consult a doctor before taking it. Lastly, use caution in pediatric patients and discuss the potential risks and benefits with a healthcare professional.
FAQs
Q 1. Can Lapenem 300mg Injection be self-administered at home?
Lapenem 300mg Injection is typically administered intravenously in a healthcare setting, such as a hospital or clinic, by trained healthcare professionals. Self-administration at home is not recommended and should only be done under a healthcare professional's strict guidance and supervision.
Q 2. Are there any specific dietary restrictions while taking Lapenem 300mg Injection?
There are generally no specific dietary restrictions associated with the use of Lapenem 300mg Injection. However, it is always advisable to maintain a balanced and healthy diet to support overall well-being and recovery from infections.
Q 3. Can Lapenem 300mg Injection cause interactions with laboratory tests?
Lapenem 300mg Injection, like other antibiotics, can interfere with certain laboratory tests, such as blood glucose tests or tests that assess kidney or liver function. If you are undergoing any laboratory tests while taking them, inform the healthcare professional conducting them to ensure an accurate interpretation of the results.
Q 4. Can Lapenem 300mg Injection be used in patients with kidney or liver disease?
Lapenem 300mg Injection should be used cautiously in patients with impaired kidney or liver function, as dosage adjustments may be necessary. It is important to provide detailed information about your medical history, including any kidney or liver conditions, to your healthcare provider to ensure safe and appropriate use.
Q 5. What are the side effects of Lapenem 300mg Injection?
Lapenem 300mg Injection can cause common side effects like gastrointestinal disturbances, skin reactions, headaches, and injection site reactions. Serious but rare side effects may include allergic reactions, seizures, and changes in liver function. Promptly report any concerning symptoms to your healthcare provider.
Fact Box of Lapenem 300mg Injection
Molecule name: Biapenem | Therapeutic class: Antibiotic |
Pharmacological class: Carbapenems
| Indications: 1. Complicated intra-abdominal infections 2. Pneumonia 3. Urinary tract infections (UTIs) 4. Septicemia 5. Skin and soft tissue infections 6. Bone and joint infections 7. Meningitis 8. Hospital-acquired infections |
References
- Sanford Guide, The Medical Management of Infectious Diseases, 7th Edition. Year 2022, 1100-1101
- Caroline M Perry; Biapenem; Drugs; [Published on 2002]; [Accessed on 8th June 2023], https://pubmed.ncbi.nlm.nih.gov/12381221/
- Amit Kaushik et al.; In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosis; Journal of Antimicrobial Chemotherapy; [Published on 01/06/2017]; [Accessed on 8/06/2023]; https://academic.oup.com/jac/article/72/8/2320/3859855
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