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  ÂLasinone 5mg Capsule
Prescription Required
Salt Composition : Nitisinone
Manufacturer : LAURUS LABS LTD
Origin of Medicine : India
60 Capsule(s) In A Bottle
Introduction to Lasinone 5mg Capsule
Lasinone 5mg Capsule is a metabolic disorders drug with an active ingredient called Nitisinone. It belongs to the family class known as enzyme inhibitors. This medicine is used to treat a rare disease called hereditary tyrosinemia type 1 (adults, adolescents, and children of all ages) and alkaptonuria (adults). It works by blocking the breakdown of the amino acid tyrosine and preventing the accumulation of harmful substances. Your physician may ask you to follow a specialized diet while taking Nitisinone for hereditary tyrosinemia type 1 (HT-1) or alkaptonuria (AKU) to manage the conditions effectively.
Lasinone 5mg Capsule should not be consumed if you are allergic to Nitisinone or any of its ingredients in the medication. Before taking this medicine, it is important to consult with your doctor. Inform your doctor if you have or have a history of any liver or kidney conditions. Notify your doctor if you have leukopenia (reduced WBC in the blood) or thrombocytopenia (reduced plated count in the blood). Your doctor will monitor platelet and white blood cell counts before initiating the treatment.Â
During the treatment, regular eye examinations will be conducted to monitor for any potential effects on the eyes. Blood samples will be taken to assess the treatment's effectiveness and detect any possible blood disorders. Regular liver check-ups will be performed if you receive Lasinone 5mg Capsule for hereditary tyrosinemia type 1. Follow-up appointments with your doctor every six months are recommended, and shorter intervals may be necessary if you experience any side effects.
Uses of Lasinone 5mg Capsule
- Hereditary tyrosinemia type 1 (adults, adolescents, and children)
- Alkaptonuria (adults)
Therapeutic Effects of Lasinone 5mg Capsule
Lasinone 5mg Capsule works by blocking the breakdown of the amino acid tyrosine, preventing its buildup in the body. This mechanism helps in the treatment of conditions such as hereditary tyrosinemia type 1 (HT-1) and alkaptonuria (AKU).
Interaction of Lasinone 5mg Capsule with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Lasinone 5mg Capsule and can cause undesirable side effects.Â
More Information about Lasinone 5mg Capsule
- Keep out of sight and reach of pets and children.
- Do not freeze the medicine.
- Do not store above 30°C.
- Always check the expiry date before consuming it.
How to consume Lasinone 5mg Capsule
Take the Lasinone 5mg Capsule as your physician advises. Usually, this capsule will be taken once a day. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the capsule if your doctor advises you to stop.
Safety Advices for Lasinone 5mg Capsule
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Pregnancy
 ÂTaking Lasinone 5mg Capsule while pregnant may be unsafe because it may affect the unborn child. Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant.
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Breast Feeding
 ÂIt is unsafe to breastfeed while taking Lasinone 5mg Capsule. Before starting the treatment, inform your doctor if you are breastfeeding.
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Lungs
 ÂIt is unknown whether Lasinone 5mg Capsule is safe for patients with lung problems. Notify your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
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Liver
 ÂLasinone 5mg Capsule should be used cautiously in liver patients. Before starting the treatment, inform your physician about pre-existing liver conditions.Â
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Alcohol
 ÂIt is unknown whether it is safe to consume alcohol while taking Lasinone 5mg Capsule. Please consult your doctor for more information.
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Driving
 ÂLasinone 5mg Capsule could alter the driving ability or operating machinery capacity by causing dizziness, headaches, nausea, and tiredness.
Side Effects of Lasinone 5mg Capsule
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Common
- Elevated levels of tyrosine
- Reduced platelet count
- Decreased lymphocyte count
- Conjunctivitis (eye inflammation)
- Corneal opacity (clouding of the cornea)
- Photophobia (sensitivity to light)
- Eye irritation (keratopathy)
- Eyelid inflammation
- Cataract (clouding of the eye's lens)
- Reduced granulocyte count
- Itching
Word of Advice
Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Liver and kidney patients should take Lasinone 5mg Capsule cautiously and inform their doctor about all the underlying medical conditions.Â
Dose adjustments will be made based on age, weight, and underlying medical conditions. Do not breastfeed while taking Lasinone 5mg Capsule. Notify your doctor if you experience any serious side effects. Contact your doctor for more information.
FAQs
Q 1. How to manage the side effects of Lasinone 5mg Capsule?
To manage the side effects of Lasinone 5mg Capsule, follow the prescribed dosage, and report side effects promptly. Stay hydrated, and monitor blood pressure regularly. Maintain a healthy lifestyle, and attend follow-up appointments.
Q 2. Can Lasinone 5mg Capsule cause vision problems?
Lasinone 5mg Capsule may cause vision problems as a side effect, including other visual disturbances, pain, irritation, and inflammation. If you experience any changes in your eye while taking Lasinone 5mg Capsule, notify your doctor immediately.
Q 3. Can you take Lasinone 5mg Capsule when pregnant?
Consult your medical professional regarding the use of Lasinone 5mg Capsule during pregnancy. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.
Q 4. What are the side effects of Lasinone 5mg Capsule?
Common side effects of Lasinone 5mg Capsule include elevated levels of tyrosine, reduced platelet count, decreased lymphocyte count, conjunctivitis (eye inflammation), corneal opacity (clouding of the cornea), and other visual problems. It is mandatory to consult your doctor for any concerns or persistent side effects.
Q 5. What should I do if I miss a dose of Lasinone 5mg Capsule?
If you miss a capsule dose, take it as soon as possible. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose the Lasinone 5mg Capsule.
Fact Box of Lasinone 5mg Capsule
Molecule Name: Nitisinone | Therapeutic class: Metabolic disorders |
Pharmacological class:Â Enzyme inhibitors | Indications:Â 1. Hereditary tyrosinemia type 1 (adults, adolescents, and children)Â 2. Alkaptonuria (adults) |
References
- LogixX Pharma Ltd, Electronic Medicines Compendium (EMC), [Revised on December 2022] [Accessed on 1st June 2023], pil.14734.pdf (medicines.org.uk)
- Apotek Produktion & Laboratorier, US Food and Drug Administration, [ Revised on November 2021] [ Accessed on 1st June 2023], https://www.orfadin.com/pdf/full-prescribing-information.pdf
- European medicines agency, [ Accessed on 1st June 2023], Orfadin | European Medicines Agency (europa.eu)
Disclaimer
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