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Lastet 50mg Capsule
Prescription Required
Salt Composition : Etoposide
Manufacturer : KHANDELWAL LABORATORIES PVT LTD
Origin of Medicine : India
8 Capsule(s) In A Bottle
Introduction to Lastet 50mg Capsule
Lastet 50mg capsule is an anticancer drug with the ingredient Etoposide. It belongs to the medication class known as cytostatic. It is used to treat certain types of cancers such as testicular cancer, small-cell lung cancer, acute myeloid leukemia (blood cancer), tumor in the lymphatic system (Hodgkin’s lymphoma, non-Hodgkin’s lymphoma), and ovarian cancer in adults.
Talk to your doctor if you had or currently having radiotherapy or chemotherapy. Report to your doctor if you have any infections or low levels of protein (albumin) in your blood. Lastet 50mg capsule should not be taken if you have recently been vaccinated with yellow fever or any live vaccines. Before starting treatment with this medicine, it is very important to tell your physician if you currently or previously had any medical conditions of kidney problems or liver disorders.
Both women and men should use effective birth control during the treatment and at least 6 months after the last dose. In men, it is recommended not to father a child during and up to 6 months after the treatment. So it is advised to get suggestions about fertility concerns from your doctor. Administration of the Lastet 50mg capsule may cause a reduction in the level of blood cells and increase the risk of developing infections. So, your doctor may perform blood tests regularly to monitor your kidney and liver function. It is unknown whether it is safe to use on a child.
Uses of Lastet 50mg Capsule
- Testicular cancer
- Small-cell lung cancer
- Acute myeloid leukemia (blood cancer)
- Hodgkin’s lymphoma and non-Hodgkin’s lymphoma
- Ovarian cancer
Therapeutic Effects of Lastet 50mg Capsule
Lastet 50mg works by inhibiting the activity of topoisomerase II (essential for cell replication) and DNA synthesis, which will prevent cancer cells from growing and multiplying, ultimately leading to cell death.
Interaction of Lastet 50mg Capsule with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications such as Ciclosporin, Phenytoin, Phenobarbitone, Warfarin, Anthracyclines, Aspirin, and Fosphenytoin may interact with Lastet 50mg and reduce effectiveness by causing undesirable side effects.
More Information about Lastet 50mg Capsule
- Keep Lastet 50mg out of sight and reach of children.
- Store at a controlled room temperature between 15°C to 30°C.
- Store in the original package
- Do not refrigerate or freeze.
How to consume Lastet 50mg Capsule
Lastet 50mg capsule is taken on an empty stomach with a glass of water. Avoid chewing, breaking, or crushing it. Your physician will choose the dosage based on your medical condition because it differs for each person.
Safety Advices for Lastet 50mg Capsule
Pregnancy
Do not take this Lastet 50mg if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment.
Breast Feeding
It is unsafe to breastfeed while taking Lastet 50mg because it can cause toxicity to the baby. Please consult your physician for more advice.
Lungs
Consult your doctor if you experience any lung-related symptoms like; shortness of breath or lung inflammation while taking an Lastet 50mg capsule.
Liver
You need to tell your doctor if you have any liver disorders before taking Lastet 50mg capsule. Your doctor may perform blood tests regularly to monitor your condition. Consult your doctor for more information.
Alcohol
It is unknown if drinking alcohol while taking an Lastet 50mg capsule is safe. Please speak with your physician.
Driving
Driving while taking an Lastet 50mg capsule is unsafe because this medicine can cause tiredness, lightheadedness, or dizziness.
Side Effects of Lastet 50mg Capsule
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Severe allergic reactions (swelling of tongue, or throat, breathing difficulties, rash, flushing, fast heartbeat)
- Irregular heartbeat (arrhythmia)
- Blood disorder
- Hepatotoxicity (damage to the liver)
- Acute leukemia
Common
- Nausea, vomiting
- Loss of appetite
- Abdominal pain
- Constipation, diarrhea
- Changes in skin color
- Weakness
- Asthenia (feeling weak)
- Temporary hair loss
- High or low blood pressure
- Dizziness
- Redness of the skin
- Sore lips, throat, or mouth ulcers
Word of Advice
Discuss your fertility problem with the doctor since, in men, it is advised not to father a child during and after the 6 months of treatment. So it is advised to get suggestions about fertility concerns. Avoid planning for the pregnancy. If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Notify your doctor immediately if you have undergone or are taking or planning any radiotherapy or chemotherapy. Inform your doctor immediately if you took any vaccines inducing yellow fever and live vaccine and other medications before starting with Lastet 50mg because it might reduce the effectiveness of this medicine and may cause side effects. Inform your doctor if you have or had any history of heart disease, kidney problems, or liver problems.
FAQs
Q 1. What should I tell my doctor before starting Lastet 50mg?
Before starting Lastet 50mg, you should tell your doctor about any medical conditions you have, especially kidney or liver problems, and any medications you are taking, including over-the-counter drugs and supplements. Inform your doctor if you had or are currently planning to take radiotherapy or chemotherapy. If you have low levels of protein (albumin) in your blood, it has to be notified to the doctor.
Q 2. How often do I need to have blood tests while on Lastet 50mg?
You will need regular blood tests while taking Lastet 50mg to monitor your liver and kidney function.
Q 3. Can Lastet 50mg cause skin problems?
Skin problems include a skin rash, dry skin, and itching. This usually goes back to normal when your treatment finishes.
Q 4. Should I use contraception even after the treatment with Lastet 50mg?
Yes, contraception is mandatory during and after treatment with Lastet 50mg for at least six months.
Q 5. What fertility concerns should be discussed while taking a Lastet 50mg capsule?
Discuss your fertility problem with the doctor since, in men, it is advised not to father a child during and after the 3 months of treatment. So it is advised to get suggestions about fertility concerns. Avoid planning for the pregnancy because it may affect your unborn baby.
Q 6. Why do I feel constipated while taking Lastet 50mg?
Constipation is a known side effect of Lastet 50mg treatment. It kills rapidly dividing cells, including cancer cells and some healthy cells in the body, such as those in the digestive tract. When the cells lining of the digestive tract are affected by this medicine, it can slow down or even stop the normal movement of waste products through the intestines, leading to constipation.
Fact Box of Lastet 50mg Capsule
Molecule name: Etoposide | Therapeutic class: Anti-Cancer |
Pharmacological class: Alkaloids-cytotoxic agents | Indication: 1. Small-cell lung cancer 2. Acute myeloid leukemia (blood cancer) 3. Hodgkin’s lymphoma and non-Hodgkin’s lymphoma 4. Ovarian cancer 5. Testicular cancer |
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1714 -1715.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 866.
- Neon Healthcare Limited, Electronic medicines compendium (emc), [ Revised on Sept 2022] [ Accessed on 29th - Mar- 2023 ], pil.10533.pdf (medicines.org.uk)
Disclaimer
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