All Substitutes
Loading...
Disclaimer
Author Details
- Reviewed By
- Dr. Tejashwin Adiga
- MBBS
Last updated Fri, 21 Mar 2025 12:11 UTC
Did you find this information helpful?
Megpro 160mg Tablet
Prescription Required
Salt Composition : Megestrol
Manufacturer : HOSPIMAX HEALTHCARE PVT LTD
Origin of Medicine : India
10 Tablet(s) In A Strip
Introduction to Megpro 160mg Tablet
Megpro 160mg Tablet contains Megestrol, a synthetic derivative of the naturally occurring hormone progesterone. It belongs to a class of medications known as progestogens and is primarily used in the management of hormone-dependent breast cancer in patients whose disease has advanced despite conventional anti-estrogen therapy. Before prescribing this medication, your physician may assess the estrogen receptor (ER) status to determine if the cancer is driven by estrogen. In addition to its use in breast cancer, Megpro 160mg Tablet is also indicated for the treatment of cachexia (muscle wasting), anorexia (loss of appetite), and unexplained weight loss in patients with cancer or weakened immune systems.
Megpro 160 uses extend beyond oncology. It helps improve appetite and restore body weight in individuals experiencing severe malnutrition due to chronic conditions. While this medication is generally well-tolerated, caution is advised in individuals with a history of thrombosis, diabetes, or adrenal insufficiency. Common side effects may include weight gain, fluid retention, and fatigue. It is essential to use this medication under the supervision of a healthcare provider, as prolonged use may lead to hormonal imbalances.
Patients taking Megpro tablets should be aware of potential contraindications, particularly in those with known hypersensitivity to Megestrol or a history of thromboembolic disorders. Proper monitoring during treatment helps mitigate the risk of adverse effects and ensures optimal therapeutic outcomes.
Uses of Megpro 160mg Tablet
Megpro 160mg tablet uses are:
- Treatment of hormone-dependent breast cancer in advanced or recurrent stages.
- Management of endometrial cancer in certain cases.
- Treatment of cachexia (muscle wasting), anorexia (loss of appetite), and unexplained weight loss in patients with acquired immunodeficiency syndrome (AIDS) or cancer.
- Supportive therapy to improve nutritional status and enhance quality of life in individuals with chronic debilitating conditions.
Therapeutic Effects of Megpro 160mg Tablet
Megpro 160mg Tablet works by mimicking the actions of natural progesterone, a hormone involved in regulating the growth of certain tissues. It slows the progression of hormone-sensitive cancers, such as breast and endometrial cancer, by inhibiting the effects of estrogen. This action prevents the cancer cells from multiplying and spreading.
In cases of cachexia and anorexia, it enhances appetite and promotes weight gain by affecting the hypothalamus (the part of the brain that controls hunger). Additionally, it alters the metabolism of proteins and fats, which helps restore body mass in patients experiencing severe weight loss due to chronic illness. By addressing both hormonal and metabolic imbalances, this medication plays a critical role in improving patients' overall condition.
Interaction of Megpro 160mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Megpro 160mg Tablet and reduce its effectiveness by causing undesirable side effects.
More Information about Megpro 160mg Tablet
- Store below 25°C.
- Protect from light and moisture.
- Keep away from children and pets.
How to consume Megpro 160mg Tablet
Megpro 160mg Tablet is taken orally and should be used exactly as prescribed by your doctor. The typical dosage for treating breast or endometrial cancer is 160 mg per day, which may be administered as a single dose or divided into smaller doses based on medical advice. It can be taken with or without food, but taking it at the same time each day ensures consistent absorption. The tablet should be swallowed whole with water, without crushing or breaking it. If a dose is missed, it should be taken as soon as possible unless it is close to the next scheduled dose. Dosage adjustments may be required depending on the patient’s response and medical condition.
Safety Advices for Megpro 160mg Tablet
Pregnancy
This medicine is unsafe to consume during pregnancy. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.
Breast Feeding
Consult your physician before taking this tablet if you are a breastfeeding mother.
Lungs
Inform your physician before starting this treatment if you have lung diseases.
Liver
Inform your physician before starting this treatment if you have liver problems. Your physician will monitor your liver functions regularly.
Alcohol
It is recommended to avoid alcohol during taking this medication as it reduces effectiveness of medication and enhances changes of side effects.
Driving
Avoid driving or using machinery if you experience side effects.
Side Effects of Megpro 160mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Swelling of the face, lips, tongue
- Skin rash
- Breathing difficulty
- Blood clot in the lungs
- Heart problems
Common:
- Weight gain and increased appetite
- Hot flushes
- High BP
- High blood sugar levels
- Rounded face
- Constipation
- Swelling of vein
- Mood changes
- Hair loss
- Diarrhea
- Tiredness and weakness
- Impotence
- Passing wind
- Frequent urination
- Nausea, vomiting
- Fluid accumulation
- Pain
Word of Advice
Inform the doctor if the patient has any history of kidney, liver, allergic reactions before starting this medication. Kidneys,liver, blood pressure and blood glucose levels should be monitored while taking this medication and avoid taking this medication while planning for pregnancy or during pregnancy as it causes harmful effects on developing babies. This medication should not be stopped without proper advice from the doctor because it can worsen the situation. Inform the doctor immediately if there are any signs of swelling and pain in the limbs, shortness of breath, chest pain, severe headache, or changes in vision.
FAQs
Q 1. Does Megpro 160mg Tablet cause weight gain?
Yes, it is a common side effect which is caused due to an increase in appetite. It leads to an increase in fat and body mass. If there is excessive weight gain patients are advised to consult the doctor.
Q 2. Does Megpro 160mg Tablet stop periods?
No, it doesn't stop periods and it can cause excessive bleeding. consult the doctor if there is any excessive bleeding.
Q 3. What are the side effects of Megpro 160mg Tablet?
The common side effects of Megpro 160mg Tablet are weight gain, increase in appetite, high blood pressure, constipation, rounded face, mood changes, hair loss, tiredness and weakness, nausea, vomiting, swelling of the vein.
Q 4. How should I take Megpro 160mg Tablet?
Megpro 160mg Tablet should be taken as prescribed by the doctor and it can be taken with or without food, preferably at the same time daily. It is important to take this medicine even when the patient is feeling well and don't stop this medication without the proper advice of the doctor as it will worsen the condition.
Fact Box of Megpro 160mg Tablet
| Molecule: Megestrol | Therapeutic class: Hormones and Hormone Antagonists
|
| Pharmacological class: Progestin | Indications: 1. Hormone-dependent cancer (endometrial cancer, breast cancer) 2. Cachexia |
References
- Bausch and Lomb UK Ltd., Electronic Medicines Compendium (EMC), [Revised on Sep 2020] [Accessed on 17th Jul 2021], https://www.medicines.org.uk/emc/files/pil.11135.pdf
- alniche Life Sciences Pvt Ltd., [Revised on 2021] [Accessed on 19th Jul 2021], https://www.alniche.com/product/megahenz/
- Bines et al., Activity of megestrol acetate in postmenopausal women with advanced breast cancer after nonsteroidal aromatase inhibitor failure: a phase II trial, Annals of Oncology, 2014, 25(4), 831-836, https://www.annalsofoncology.org/action/showPdf?pii=S0923-7534%2819%2936501-9
- G.G. Dark, A.R. Abdul Razak, Oncology, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 259-282.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
