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MESNA 200MG INJECTION_1
MESNA 200MG INJECTION_2
MESNA 200MG INJECTION_3
MESNA 200MG INJECTION_1

Mesna 200mg Injection

Prescription Required

Salt Composition : Mesna

Manufacturer : ZYDUS CADILA

Origin of Medicine : India

MRP: ₹28
Price : ₹28
You Save : ₹0 (0%)

1 Ampoule(s) Of 2ml

Pincode
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Introduction to Mesna 200mg Injection

Mesna 200mg injection contains the active substance Mesna. It is a cytoprotective drug that belongs to the class of hemorrhagic cystitis inhibitors. This medicine reduces the risk of hemorrhagic cystitis (a condition that causes bladder inflammation and can result in serious bleeding) in people who receive ifosfamide (a medication used for treating cancer). It protects against some of the harmful effects of certain chemotherapy medications.  

Do not take this injection if you are allergic to Mesna 200mg injection or any other ingredients of this medicine. This medicine can cause serious allergic reactions and skin reactions. Inform your doctor if you face any symptoms of fever, swelling of your face, lips, mouth, or tongue, trouble breathing or wheezing, itching, burning, skin rash or hives, skin redness, or swelling after taking this medicine.  

Notify your physician if you are pregnant or breastfeeding or have severe liver and bladder problems. Female patients should use effective contraception during the treatment with Mesna 200mg injection in combination with other anticancer medication and for 6 months after the last dose. The most common side effects are nausea, vomiting, constipation, decreased platelets and WBC levels, tiredness, fever, abdominal pain, headache, hair loss, and difficulty sleeping.

Uses of Mesna 200mg Injection

  • Hemorrhagic cystitis

Therapeutic Effects of Mesna 200mg Injection

Mesna 200mg injection reduces ifosfamide (cancer medication) induced hemorrhagic cystitis by binding to certain metabolites, inhibiting their toxic effects on the bladder. 

Interaction of Mesna 200mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Mesna 200mg injection and reduce their effectiveness by causing undesirable side effects.

More Information about Mesna 200mg Injection

  • Store Mesna 200mg injection in the refrigerator (20°C to 25°C)
  • Do not freeze
  • keep the injection away from the reach of children and pets.
  • If you have missed any dosing appointments, inform your doctor and schedule immediately.

How to consume Mesna 200mg Injection

It should only be administered by a trained doctor or nurse experienced in administering chemotherapy. The medicine will be given as an infusion into a vein. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors. 

Safety Advices for Mesna 200mg Injection

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Pregnancy

  

There are limited human studies on the safety of Mesna 200mg injection during pregnancy. Consult your doctor if you are pregnant, suspecting, or planning for pregnancy. 

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Breast Feeding

  

Breastfeeding is not recommended in patients taking Mesna 200mg injection because the medicine secrete into the breast milk in small amounts and may harm your baby. 

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Lungs

  

It is unknown whether Mesna 200mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

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Liver

  

Mesna 200mg injection should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary. Inform your physician if you have liver problems before initiating the therapy.  

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Alcohol

  

It is unknown whether consuming alcohol will affect the effectiveness of Mesna 200mg injection. Consult your doctor for more advice. 

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Driving

  

Mesna 200mg injection affects the ability to drive or operate heavy machines. It is unsafe to drive or operate heavy machinery. 

Side Effects of Mesna 200mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. 

Common 

  • Chest pain
  • Swelling in the face, feet, and hands
  • Hair loss
  • Excessive sweating
  • Decreased potassium levels
  • Abdominal pain
  • Constipation
  • Diarrhea, loss of appetite
  • Nausea, vomiting
  • Anemia
  • Changes in the blood count levels
  • Backache
  • Confusion, dizziness, headache
  • Fever, tiredness

Serious 

  • Rash
  • Hypersensitivity reactions

Word of Advice

Drink more fluids so you will urinate more often and help prevent kidney problems. Drink 1 to 2 liters of fluid each day. Male patients with female partners should use an effective form of birth control during treatment and for 3 months after the last dose. Do not breastfeed during the treatment with this medicine and for 1 week after the last dose. Your physician may take regular lab tests to check for the effectiveness of the therapy and monitor you for any unwanted effects of the medicine. 

FAQs

Q 1. What if Mesna 200mg injection does not work for me?

There are alternative medicines that may work for you based on your disease condition and other factors. Your doctor will decide the alternative treatment that works best for you.

Q 2. Is there any special diet that I should follow while taking Mesna 200mg injection?

There are no special restrictions on the diet. If your doctor or any other healthcare professional tells you to avoid certain food, then avoid it. Diet restrictions may vary from patient to patient. Consult your doctor for more advice.

Q 3. Why is Mesna 200mg injection contraindicated in neonates, premature and low-birth-weight babies?

The preservative benzyl alcohol added in the Mesna 200mg injection has been associated with serious adverse reactions and death in neonates and premature infants. Consult your doctor for more information.

Q 4. Can old-age patients take Mesna 200mg injection?

Dose selection should be cautiously made in older age people receiving Mesna 200mg injection. Your physician will decide the dose and duration of the therapy.

Q 5. What are the precautions I should follow while receiving Mesna 200mg injection?

Drink 1 to 2 liters of fluid each day during the therapy with Mesna 200mg injection. Inform your physician of any symptoms of bleeding or skin reactions.

Fact Box of Mesna 200mg Injection

Molecule name: Mesna

Therapeutic class: Cytoprotectants

Pharmacological class: Hemorrhagic cystitis inhibitor 

Indications: Prevent hemorrhagic cystitis

References

  1. HIGHLIGHTS OF PRESCRIBING INFORMATION - Mesna [revised on 2014] [cited 2023 Apr 6]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/019884s013lbl.pdf
  2. Boehringer-Ingelheim, Mesna  [Revised on March 2014] [ Accessed on 06 April 2023], https://docs.boehringer-ingelheim.com/Prescribing%20Information/PIs/Ben%20Venue_Bedford%20Labs/55390-045-01%20MSN%201G/5539004501
  3. V Reddy, Winston NR; Mesna; NCBI Bookshelf; [Revised on Nov 2020] [Accessed on 06th April 2023], https://www.ncbi.nlm.nih.gov/books/NBK556021/

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