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Murinact 4gm Injection
Prescription Required
Salt Composition : Fosfomycin
Manufacturer : FUSION HEALTH CARE PVT LTD
Origin of Medicine : India
1 Ampoule(s)
Introduction to Murinact 4gm Injection
Murinact 4gm Injection belongs to a class of drugs called phosphonic antibiotics containing the active ingredient Fosfomycin. It is used to treat bacterial infections, particularly uncomplicated urinary tract infections (UTIs) in women caused by susceptible bacteria. It is effective against a wide range of gram-negative and gram-positive bacteria. This drug is also used to prevent possible infections before prostate surgical procedures in adult men. Administering the medication before the surgery can help reduce the risk of post-operative infections.
If you have a history of experiencing diarrhea after taking antibiotics, you must inform your physician before initiating the treatment. Certain antibiotics, including this drug, can sometimes cause gastrointestinal side effects like diarrhea, and this information helps your doctor assess any potential risks or alternatives. Murinact 4gm Injection is generally not recommended for use in children under 12 years old. The safety and efficacy of this drug in younger children have not been well-established, and therefore, it is usually avoided in this age group.
Some formulations of this drug contain sucrose. If you have a known intolerance to certain sugars, such as lactose or sucrose, it's important to inform your doctor. They can check the medication's ingredients to ensure it is safe for you to use. Contact your physician immediately if you develop any unexpected side effects or adverse reactions while taking this drug. If you are pregnant, breastfeeding, or planning for the pregnancy, consult your physician for more advice before taking Murinact 4gm Injection. Physicians may prescribe this medicine only when it is needed.
Uses of Murinact 4gm Injection
- Treat uncomplicated urinary tract infections (UTIs)
Therapeutic Effects of Murinact 4gm Injection
Murinact 4gm Injection works by inhibiting the synthesis of bacterial cell walls, leading to the death of susceptible bacteria.
Interaction of Murinact 4gm Injection with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Murinact 4gm Injection and reduce effectiveness by causing undesirable side effects.
More Information about Murinact 4gm Injection
- Keep Murinact 4gm Injection out of reach of children and pets.
- Protect from light and moisture.
How to consume Murinact 4gm Injection
Murinact 4gm Injection is administered directly into the vein intravenously (IV). It is available as a powder for reconstitution, and a physician will prepare and administer the medication through a vein. The IV infusion is usually given over a period of one to two hours.
Safety Advices for Murinact 4gm Injection
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Pregnancy
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If you are pregnant, suspecting, or planning for the pregnancy, consult your physician for more advice before taking Murinact 4gm Injection. Physicians may prescribe this medicine only when it is needed.
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Breast Feeding
 ÂIf you are a breastfeeding mother, it's important to consult with your doctor before taking Murinact 4gm Injection.
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Lungs
  It is unknown whether Murinact 4gm Injection is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.
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Liver
  It is unknown whether Murinact 4gm Injection is safe for patients with liver problems. Inform your physician if you have liver disease before starting the treatment.
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Alcohol
 ÂIt is unknown whether consuming alcohol while taking Murinact 4gm Injection is safe. Please speak with your physician.
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Driving
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Some side effects of Murinact 4gm Injection may impair your ability to drive or operate machinery safely. It is unsafe to consume this drug.
Side Effects of Murinact 4gm Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Serious allergic reactions (sudden onset of itching, rash or hives on the skin, shortness of breath and wheezing)
- Swelling of the face, lips, tongue or throat
- Moderate to severe abdominal cramps
- Bloody stools
- Fever
Common
- Headache
- Dizziness
- Diarrhea
- Nausea
- Indigestion
- Abdominal pain
- Infection of the female genital organs
Word of Advice
Take Murinact 4gm Injection exactly as your physician prescribes and complete the full course of treatment, even if you start feeling better before the medication is finished. Incomplete courses of antibiotics can contribute to antibiotic resistance and the recurrence of infections. If you suspect you have a bacterial infection or UTI symptoms, it's necessary to consult your physician for proper evaluation and treatment recommendations.
FAQs
Q 1. What infections does Murinact 4gm Injection treat?
Murinact 4gm Injection is primarily used to treat uncomplicated urinary tract infections (UTIs) caused by certain susceptible bacteria, particularly Escherichia coli (E. coli), which is a common pathogen responsible for UTIs. It may also be prescribed for other bacterial infections, but its use is generally limited to UTIs.
Q 2. How is Murinact 4gm Injection administered?
Murinact 4gm Injection is available in several forms, including oral granules, sachets, and intravenous (IV) preparations. For uncomplicated UTIs, it is often given as a single oral dose. A course of IV treatment may be prescribed for more severe or complicated infections.
Q 3. Can Murinact 4gm Injection be used to prevent UTIs?
Murinact 4gm Injection is primarily used for the treatment of UTIs, not for prevention. If you experience recurrent UTIs, your physician may suggest other preventive measures or medications.
Q 4. Is Murinact 4gm Injection effective against antibiotic-resistant bacteria?
Murinact 4gm Injection can still be effective against some antibiotic-resistant bacteria, including certain strains of multidrug-resistant E. coli. However, susceptibility testing is necessary to determine if the specific bacterial strain causing the infection is susceptible to this drug.
Q 5. Can I drink alcohol while taking Murinact 4gm Injection?
It is generally recommended to avoid alcohol consumption while taking antibiotics, including Murinact 4gm Injection. Alcohol can interfere with the effectiveness of antibiotics and may also exacerbate certain side effects.
Fact Box of Murinact 4gm Injection
Molecule name: Fosfomycin | Therapeutic class: Urinary anti-infectives |
Pharmacological class:Â Phosphonic antibiotics | Indications: Treat uncomplicated urinary tract infections (UTIs) |
References
- Parapharm Development Limited, Electronic medicines compendium (EMC), [Revised on June 2023] [ Accessed on 19th August 2023], https://www.medicines.org.uk/emc/files/pil.12553.pdf
- Zambon Switzerland Ltd, US Food and Drug Administration, [Revised on July 2007] [ Accessed on 19th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050717s005lbl.pdf
- Fosfomycin for injection - pdf.hres.ca. [Revised on May 2019] [Accessed on 19th August 2023] https://pdf.hres.ca/dpd_pm/00050889.PDF
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Agents for Urinary Tract Infections, 12th edition, 2011, 1467.
- Bertram G. Katzung, Lange's Basic and Clinical Pharmacology, Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics, 14th Edition, 2018, 811.
Disclaimer
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