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Nefrosave Forte Tablet
Prescription Required
Salt Composition : Acetylcysteine,pyridoxamine Dihydrochloride
Manufacturer : FOURRTS INDIA PVT LTD
Origin of Medicine : India
15 Tablet(s) In A Strip
Introduction to Nefrosave Forte Tablet
Nefrosave forte tablet consists of the active substances N-acetylcysteine 300mg and pyridoxamine dihydrochloride 50mg. It is used in the management of diabetic nephropathy and as an antidote for paracetamol poisoning. Diabetic nephropathy is a crucial factor leading to end-stage kidney disease. It is a result of various factors such as poor glycaemic control, prolonged diabetes, hypertension, family history, and other complications. This medicine protects the kidney from injury caused by contrast media, ischemia and toxins. It also detoxifies the body from the effects of over-dosage of paracetamol.
Individuals with allergic reactions to the ingredients and severe infections should consult their doctor before taking the nefrosave forte tablet . Talk to your doctor immediately if you have any allergic reaction (difficulty with breathing, chest tightness rash, itching, hives, swelling lips, tongue, or face), infection (short- or long-term), tuberculosis, intestinal ulcers or diverticulitis (small bulging pouches developed in the digestive tract), liver disease, cancer, kidney function problems, and persistent headaches. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding.
Uses of Nefrosave Forte Tablet
- Diabetic nephropathy
- Paracetamol poisoning
- Radiocontrast induced nephropathy
Therapeutic Effects of Nefrosave Forte Tablet
Nefrosave forte tablet works by preventing the excretion of protein in urine. Pyridoxamine dihydrochloride is derived from Vitamin B6. It inhibits the formation of advanced glycation end products (AGE) and helps delay the progression of diabetic nephropathy to end-stage renal disease.
Interaction of Nefrosave Forte Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with nefrosave forte tablet and can cause undesirable side effects.
More Information about Nefrosave Forte Tablet
- Protect from light and moisture
- Store at 25°C
- Keep children away from the sight and reach of this medication.
How to consume Nefrosave Forte Tablet
Take nefrosave forte tablet as your physician advises. Swallow the tablets whole and intact. This capsule should be taken with food. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the medicine if your doctor advises you to stop.
Safety Advices for Nefrosave Forte Tablet
Pregnancy
Consult your healthcare provider if you plan to get pregnant. However, the medication has not been given to expectant mothers, and it should only be used when the projected advantages outweigh any possible hazards to the fetus.
Breast Feeding
It is unknown whether nefrosave forte tablet is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Consult your doctor for more information.
Lungs
It is unknown whether nefrosave forte tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Liver
Inform your physician about any underlying liver disorders before taking nefrosave forte tablet, as this medication should be used cautiously in liver disease patients.
Alcohol
It is unknown whether it is safe to consume alcohol under medication. So, it is recommended to consult your doctor before taking medicine.
Driving
It is not known whether it is safe to drive while taking a nefrosave forte tablet. Consult your doctor for more information.
Side Effects of Nefrosave Forte Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Allergic reaction (difficulty with breathing, chest tightness, rash, itching, hives, swelling in the lips, tongue, or face)
- Fever and chills
- Mouth or skin blisters
- Stomach ache.
Common
- Nausea
- Vomiting
- Diarrhea
Word of Advice
Talk to your doctor if you have recently been vaccinated or are planning a vaccination because a certain vaccination (live vaccine) should not be given while taking nefrosave forte tablet medicine. Your doctor will advise you to check the blood if you have low white blood cells, platelets, or elevated liver enzymes before giving you the medicine. Drink plenty of water and take electrolytes to compensate for the water loss due to vomiting.
FAQs
Q 1. Can I take nefrosave forte tablet for paracetamol poisoning?
Yes, you can take nefrosave forte tablet. It detoxes the body from the effects of overdosage of paracetamol. It is recommended to consult your doctor.
Q 2. Do I have vomiting while taking nefrosave forte tablet?
Yes, you may have vomiting during the Nefrosave forte tablet medication. Drink plenty of water and take electrolytes to compensate for the water loss due to vomiting.
Q 3. What is the use of nefrosave forte tablet?
Nefrosave forte tablet is used in the management of diabetic nephropathy and as an antidote for paracetamol poisoning.
Q 4. How to consume a nefrosave forte tablet?
Take Nefrosave forte tablet as your physician advises. Swallow the tablets whole and intact. This capsule should be taken with food. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the medicine if your doctor advises you to stop.
Q 5. Can I take nefrosave forte tablet If I am allergic to it?
You should consult the doctor if you are allergic to Nefrosave forte tablet before using it.
Fact Box of Nefrosave Forte Tablet
Molecule name: Acetylcysteine + pyridoxamine dihydrochloride | Therapeutic class: Anti-diabetic nephropathy |
Pharmacological class: Advanced glycation end products (AGE) inhibitor | Indications: 1. Diabetic nephropathy 2. Paracetamol poisoning 3. Radiocontrast-induced nephropathy |
References
- Alniche Life Sciences Pvt Ltd., [Revised on 2021] [Accessed on 29th Jul 2021], https://www.alniche.com/product/renosave/
- Panpharma GmbH. Electronic Medicines Compendium (EMC), [Revised on December 2019] [Accessed on Nov 2023], pil.3447.pdf (medicines.org.uk)
- Parvin Mazraati and Mohsen Minaiyan, Hepatoprotective Effect of Metadoxine on Acetaminophen-induced Liver Toxicity in Mice, Published on 24 april 2014, [Accessed on Nov 2023], https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952541/
- E.R. Pearson, R.J. McCrimmon, Diabetes mellitus, Davidson's Principles & Practice of Medicine, 22nd Edition, 2014, 797-836.
Disclaimer
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