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Nitroplus 50mg Injection
Prescription Required
Salt Composition : Nitroglycerin
Manufacturer : NEON LABORATORIES LTD
Origin of Medicine : India
1 Ampoule(s) Of 10ml
Introduction to Nitroplus 50mg Injection
Nitroplus 50mg injection contains an active ingredient called Nitroglycerin which belongs to the group of medicines called nitrates. This medication is used in various conditions, including heart failure and acute myocardial infarction (heart attack). It is also effective in treating angina attacks and can help lower blood pressure during surgery. Additionally, it is used to control blood pressure during and after cardiac surgery, providing vital support to the heart. This medicine works by relaxing the muscles around blood vessels; it eases the heart's workload and provides relief from angina pain.
Do not take this medicine if you are allergic to nitroglycerin or any other nitrates or if you are taking medication for erectile dysfunction such as sildenafil (Viagra), vardenafil, or tadalafil. Combining Nitroplus 50mg injection with these medicines can cause a dangerous drop in blood pressure, leading to collapse and even fatality. Avoid using this medicine if you are in shock or have severe anemia, low blood pressure, low blood volume, or low blood oxygen. It is also not recommended if you have certain heart conditions, fluid accumulation in the lung, or a history of head injuries or cerebral hemorrhage. Additionally, if you are using riociguat for treating pulmonary hypertension, avoid taking this.Â
Always consult your doctor before using Nitroplus 50mg injection to ensure it is safe and suitable for your health. Before taking medicine, inform your doctor if you have certain heart conditions (acute left-sided heart failure, heart attack), liver or kidney problems, thyroid issues, hypothermia, or if you are pregnant or breastfeeding. It is advised not to be used in children.
Uses of Nitroplus 50mg Injection
- Heart failure and acute myocardial infarction (heart attack).
- Angina attack.
- Lowering blood pressure during surgery.
- Controlling blood pressure during and after cardiac surgery.
Therapeutic Effects of Nitroplus 50mg Injection
Nitroplus 50mg injection works by relaxing and widening the blood vessels, which improves blood flow, reduces the heart's workload, and relieves the chest pain (angina).
Interaction of Nitroplus 50mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications such as sildenafil (Viagra), vardenafil, tadalafil) may interact with Nitroplus 50mg injection and can cause undesirable side effects.Â
More Information about Nitroplus 50mg Injection
- Keep out of sight and reach of pets and children.
- Store the medicine below 25°C.
- Always check the expiry date before consuming it.
How to consume Nitroplus 50mg Injection
Nitroplus 50mg injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered in a vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Safety Advices for Nitroplus 50mg Injection
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Pregnancy
 ÂLimited information is available on the usage of Nitroplus 50mg injection during pregnancy. Before starting the treatment, inform your doctor if you are pregnant or planning to get pregnant or think you may be pregnant.Â
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Breast Feeding
 ÂLimited information is available on the usage of Nitroplus 50mg injection during breastfeeding. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.Â
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Lungs
 ÂIt is unknown whether Nitroplus 50mg injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
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Liver
 ÂNitroplus 50mg injection should be used cautiously in patients with liver conditions. Before starting the treatment, inform your physician about pre-existing liver conditions.Â
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Alcohol
 ÂAvoid alcohol while using Nitroplus 50mg injection as it can cause a drop in blood pressure, leading to dizziness or fainting.
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Driving
 ÂIt is unknown whether Nitroplus 50mg injection alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.Â
Side Effects of Nitroplus 50mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Common
- Sleepiness
- Low blood pressure (hypotension)
- Light-headedness
- Dizziness
- Drowsiness
- Rapid heartbeat
Word of Advice
Patients with liver, heart, and kidney conditions should take Nitroplus 50mg injection cautiously and should inform the doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.Â
FAQs
Q 1. Can I use Nitroplus 50mg injection if I’m pregnant?
Consult your medical professional regarding the use of Nitroplus 50mg injection during pregnancy. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.
Q 2. Can I take Nitroplus 50mg injection with medications for erectile dysfunction?
No, Nitroplus 50mg injection should not be taken with medicines for erectile dysfunction (e.g. Viagra) as it can cause a severe drop in blood pressure, leading to a medical emergency. Contact your doctor for more information.
Q 3. Can I drink alcohol while using Nitroplus 50mg injection?
It is advisable to avoid alcohol while using Nitroplus 50mg injection, as it can cause a drop in blood pressure, leading to dizziness or fainting.
Q 4. What should I do if I have a bad reaction to Nitroplus 50mg injection?
If you have a bad reaction to Nitroplus 50mg injection, such as a severe headache, dizziness, or fainting, stop taking the medication and contact your doctor right away. Your doctor may reduce the next dose or prescribe any over counter medicine to manage the side effects.
Q 5. What happens if I take Nitroplus 50mg injection too often?
Taking Nitroplus 50mg injection too often can lead to tolerance, where the medication becomes less effective over time. If you suspect you are using it excessively, consult your doctor for proper guidance.
Fact Box of Nitroplus 50mg Injection
Molecule Name: Nitroglycerin | Therapeutic class: Antianginal agents |
Pharmacological class: Nitrates | Indications: 1. Heart failure and acute myocardial infarction (heart attack). 2. Angina attack. 3. Lowering blood pressure during surgery. 4. Controlling blood pressure during and after cardiac surgery |
References
- Hameln Pharma Ltd, Electronic medicines compendium (emc), [Revised on April 2021] [ Accessed on 24th July 2023], https://www.medicines.org.uk/emc/files/pil.6296.pdfÂ
- Baxter, US Food and Drug Administration, [Revised on Oct 2014] [ Accessed on 24th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/019970s015lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Treatment of myocardial ischemia and hypertension, 12th edition, 2011, 753.
- KD Tripathi, Essentials of Medical Pharmacology, Antianginal and other anti-ischaemic drugs, 7th edition, 2013, 543.
Disclaimer
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