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NOR EPINEPH INJECTION_1
NOR EPINEPH INJECTION_2
NOR EPINEPH INJECTION_3
NOR EPINEPH INJECTION_1
48% Off

NOR Epineph Injection

Prescription Required

Salt Composition : Noradrenaline

Manufacturer : THEMIS MEDICARE

Origin of Medicine : India

MRP: ₹57.53
Price : ₹30
You Save : ₹28 (48%)

1 Ampoule(s) Of 2ml

Not for Sale
Pincode
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Introduction to Nor Epineph Injection

Nor epineph injection contains an active component of Noradrenaline. It is a neurotransmitter and hormone that plays a crucial role in various physiological functions, including regulating blood pressure and the "fight or flight" response.  It is used as a medication for various problems like hypotension (low blood pressure), septic shock, cardiac arrest, anaphylactic shock, bradycardia, cardiogenic shock, regional anesthesia, and nasal congestion. Septic shock is a life-threatening condition characterized by a severe systemic infection that causes a drop in blood pressure, organ dysfunction, and inadequate blood flow to vital organs of the body. Cardiogenic shock is a critical condition where the heart's ability to pump blood is severely compromised, leading to inadequate blood flow to organs and tissues, often resulting from a heart attack or severe heart failure. 

The Nor epineph injection can cause sensitivity reactions, ranging from skin problems to severe allergic responses. It should be used cautiously and avoided if someone is allergic to it. People with a specific adrenal gland tumor called pheochromocytoma shouldn't use Nor epineph injection, as it could worsen their condition. To ensure Nor epineph injection is used safely and effectively, it's important to consider these factors and talk to a doctor specializing in treating children before giving it to them. Similarly, involving a doctor specializing in senior care is important for older adults. They will focus on finding the right dose, slowly adjusting it, considering other medications the person is taking, and keeping a close watch on their health. This is crucial because how the body responds to medications can change as we age.

Uses of Nor Epineph Injection

Nor epineph injection is used in the following:

  • Hypotension management
  • Septic shock treatment
  • Cardiac arrest and bradycardia
  • Anaphylactic shock intervention
  • Cardiogenic shock support
  • Regional anesthesia augmentation
  • Nasal decongestion

Therapeutic Effects of Nor Epineph Injection

Nor epineph injection acts as a neurotransmitter and hormone. It binds to adrenergic receptors on target cells, particularly α1 and α2 adrenergic receptors, leading to vasoconstriction, increased heart rate, and enhanced cardiac contractility. This results in elevated blood pressure and improved perfusion in critical situations.

Interaction of Nor Epineph Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Nor epineph injection, reducing effectiveness by causing undesirable side effects. 

More Information about Nor Epineph Injection

  • Store at room temperature, up to 20°C to 25°C.
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Nor Epineph Injection

Nor epineph injection is primarily administered intravenously (IV). It's typically given as a continuous infusion through a dedicated IV line under the supervision of trained medical personnel. The IV route allows for precise control of the medication's effects and rapid dosage adjustment in critical situations. This medication requires careful monitoring of vital signs and the patient's response to ensure its safety and efficacy.

Safety Advices for Nor Epineph Injection

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Pregnancy

  

Nor epineph injection's effect on pregnancy is not extensively studied so it is important to consult a healthcare provider before use during pregnancy.

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Breast Feeding

  

It is important to consult a healthcare professional before using it during pregnancy.

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Lungs

  

Patients with lung conditions like chronic obstructive pulmonary disease (COPD) or asthma should consult a healthcare provider before taking Nor epineph injection.

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Liver

  

Patients with liver dysfunction should consult a healthcare provider before taking Nor epineph injection. 

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Alcohol

  

Alcohol consumption should be avoided while receiving Nor epineph injection treatment as it is unsafe during treatment. Alcohol can interact with Nor epineph injection, potentially leading to adverse effects like increased blood pressure and heart rate. 

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Driving

  

Nor epineph injection can cause side effects like increased heart rate and changes in blood pressure, which could affect concentration and alertness. So it is unsafe to drive while taking this medication. 

Side Effects of Nor Epineph Injection

Nor epineph injection causes some side effects like all medications, although not everyone will experience them. 

Serious

  • Hypertensive crisis
  • Arrhythmias
  • Ischemia
  • Extravasation
  • Pulmonary hypertension

Common

  • Increased heart rate
  • Increased blood pressure
  • Headache
  • Nervousness and anxiety
  • Nausea and vomiting
  • Pale or cool skin
  • Dizziness
  • Shortness of breath

Word of Advice

There are important steps to follow when using Nor epineph injection for safety. Patients require close monitoring by healthcare professionals while taking this medication. In some cases, dose adjustment is required based on the person's age and how they react. Patients should check closely things like heart rate, blood pressure, and how their body responds. Consider potentially serious effects like high blood pressure or heart rhythm problems. Take care when putting the IV line in and avoid leaks. Patients should be aware of any side effects and contact their doctor if they face any difficulty during treatment.

FAQs

Q 1. What should I do if I miss a dose of Nor epineph injection?

Nor epineph injection is usually given as a continuous infusion, so missed doses are less likely. However, if there's any interruption, notify your healthcare provider immediately to prevent sudden drops in blood pressure.

Q 2. Can Nor epineph injection be self-administered at home?

No, Nor epineph injection requires skilled medical administration and monitoring, usually in a hospital or clinical setting. It's not suitable for self-administration.

Q 3. Can Nor epineph injection cause dependency?

Under proper medical supervision, Nor epineph injection used for medical purposes is not known to cause dependency.

Q 4. Can I eat or drink while receiving Nor epineph injection?

Your healthcare provider will guide you on dietary restrictions, if any, during Nor epineph injection treatment. Sometimes, oral intake might be restricted depending on the medical situation.

Q 5. Can Nor epineph injection cause mental health changes?

While Nor epineph injection primarily affects cardiovascular functions, its stimulating effects might contribute to feelings of nervousness or anxiety in some individuals. If you notice significant mental health changes, discuss them with your healthcare provider.

Q 6. Can certain individuals be more prone to side effects of Nor epineph injection?

Individuals with preexisting heart conditions, hypertension, or other medical issues might be more sensitive to Nor epineph injection's effects and more prone to experiencing side effects.

Fact Box of Nor Epineph Injection

Molecule name:  Noradrenaline

Therapeutic class: vasopressor

Pharmacological class: Alpha-adrenergic agonists

Indications: 

1. Hypotension management

2. Septic shock treatment

3. Cardiac arrest and bradycardia

4. Anaphylactic shock intervention

5. Cardiogenic shock support

6. Regional anesthesia augmentation

7. Nasal decongestion

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Adrenergic agonists and antagonists, 12th edition, 2011, 287.
  2. KD Tripathi, Essentials of Medical Pharmacology, Adrenergic system and drugs, 7th edition, 2013, 133.
  3. Hospira UK Limited, Electronic medicines compendium (EMC), [Revised on 18 Aug 2022] [Accessed on 14th August 2023], https://www.medicines.org.uk/emc/product/4115/pil
  4. Baxter Healthcare Corporation, US Food and Drug Administration, [Revised on Jan 2021] [Accessed on 14th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/214313s000lbl.pdf

Disclaimer

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