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Nordiflex 10mg Injection
Prescription Required
Salt Composition : Somatropin/recombinant Human Growth Hormone
Manufacturer : NOVO NORDISK INDIA PVT LTD
Origin of Medicine : Denmark
1 Prefilled Syringe(s) Of 1.5ml
Introduction to Nordiflex 10mg Injection
Nordiflex 10mg injection is a hormonal drug in the human growth hormone (hGH) agonist category, containing the active ingredient Somatropin. It treats growth failure in children due to deficiency of growth hormone, Turner’s syndrome, small for gestational age, and short stature of unknown cause. Apart from treating growth hormone deficiency, treatment with this medication also helps improve muscle mass, exercise capacity, bone mineral density and decreases fat mass.
This drug is contraindicated in severe obesity, acute critical illness, upper airway obstruction, sleep apnea, cancer, diabetes, impaired glucose tolerance, hypersensitivity, hypothyroidism, hypoadrenalism, scoliosis, and pancreatitis. Contact your doctor immediately if you experience breathlessness, rapid heartbeat, severe rash, swelling of arms or legs, or any other anaphylactic reactions. During treatment with Nordiflex 10mg injection, your doctor may periodically monitor your blood count, blood sugar, thyroid, and other vital parameters to prevent serious complications.Â
Report to your doctor if you have had a history of diabetes, heart problems, hypothyroidism, pancreatitis, cancer, obesity, or acute illnesses. It is not known whether treatment with this drug alters fertility. Consult your doctor for more advice. Nordiflex 10mg injection is not safe to be used during pregnancy. Report to your doctor if you are pregnant, suspecting, or planning for the pregnancy before starting the treatment. It is highly advised to use this injection with caution during breastfeeding.
Uses of Nordiflex 10mg Injection
- Growth failure due to growth hormone deficiency
Therapeutic Effects of Nordiflex 10mg Injection
Nordiflex 10mg injection is equivalent to the human pituitary hormone that helps in growth. It regulates the amount of insulin-like growth factor-I (IGF-I) and improves linear growth in patients with growth hormone deficiency.
Interaction of Nordiflex 10mg Injection with other drugs
Inform your physician about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Nordiflex 10mg injection and cause undesirable side effects.
More Information about Nordiflex 10mg Injection
- Store Nordiflex 10mg injection in a refrigerator (2°C-8°C).
- Do not freeze.
How to consume Nordiflex 10mg Injection
Nordiflex 10mg injection will be given under the skin (subcutaneously). Your doctor, nurse, or other healthcare professional will show you how to inject the medicine. Do not try to administer the medicine if you are well-trained. Your physician will decide the injection dose based on your disease condition and severity.
Safety Advices for Nordiflex 10mg Injection
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Pregnancy
 ÂNordiflex 10mg injection is not safe to be used during pregnancy. Report to your doctor if you are pregnant, suspecting, or planning for the pregnancy before starting the treatment.
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Breast Feeding
 ÂNordiflex 10mg injection is used with caution in breastfeeding women. Consult with your physician for advice.
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Lungs
 ÂIt is unknown whether Nordiflex 10mg injection is safe for patients with lung problems. Contact your doctor for more advice.
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Liver
 ÂIt is unknown whether Nordiflex 10mg injection is safe for patients with liver problems. Contact your doctor for more advice.
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Alcohol
 ÂIt is unknown whether consuming alcohol while taking a Nordiflex 10mg injection is safe. Please speak with your physician.
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Driving
 ÂNordiflex 10mg injection does not affect your ability to drive and operate heavy machines.
Side Effects of Nordiflex 10mg Injection
Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them.
Serious
- Visual changes
- Intracranial hypertension
Common
- Swelling
- Arthralgia
- Upper respiratory tract infection
- Pain
- Edema
- Paraesthesia
- Headache
- Stiffness
- Tiredness
- Muscle pain
- Back pain
Word of Advice
You should avoid driving or handling machines if you experience dizziness, tiredness, or any visual disturbances. Maintain adequate nutrition and fluid intake. Avoid consuming carbonated drinks and alcohol while on treatment with Nordiflex 10mg injection.
FAQs
Q 1. How does Nordiflex 10mg injection work?
Nordiflex 10mg injection stimulates the production of insulin-like growth factor-1 (IGF-1) in the liver and other tissues. IGF-1 promotes growth and development by stimulating the growth of bones, cartilage, and muscles.
Q 2. How is Nordiflex 10mg injection administered?
Nordiflex 10mg injection is administered as a subcutaneous injection, which is injected just under the skin. The injection site can vary, but common areas include the thigh, buttocks, or abdomen. A physician should provide specific dosage and administration instructions.
Q 3. Is Nordiflex 10mg injection available over the counter?
No, Nordiflex 10mg injection is a prescription medication and is not available over the counter. It requires a prescription from a physician, and its use should be closely monitored.
Q 4. What are the side effects of Nordiflex 10mg injection?
Common side effects of Nordiflex 10mg injection can include injection site reactions, headache, joint pain, muscle pain, swelling of the hands or feet, and high blood sugar levels.
Q 5. Are there any risks associated with Nordiflex 10mg injection use?
While Nordiflex 10mg injection is generally safe when used as prescribed, some risks are associated with its use. Excessive doses or long-term use can lead to acromegaly (excessive growth of the hands, feet, and face), increased risk of diabetes, fluid retention, and increased pressure within the skull. Close monitoring is necessary to minimize the risk.
Fact Box of Nordiflex 10mg Injection
Molecule Name: Somatropin/Recombinant Human Growth Hormone | Therapeutic class:Â Growth Hormones |
Pharmacological class: Human growth hormone (hGH) agonist | Indications: Growth failure due to growth hormone deficiency |
References
- Ipsen Pharma, Electronic Medicines Compendium (EMC), [Revised on March 2022], [Accessed on 28th June 2023] Available at: https://www.medicines.org.uk/emc/files/pil.58.pdf
- Norditropin Injection - food and drug administration (FDA). [Revised on Feb 2018], [Accessed on 28th June 2023] Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021148s037s038lbl.pdf
- Goodman & Gilman’s Pharmacological Basis of Therapeutics, Introduction to Endocrinology: The Hypothalamic-Pituitary Axis, 2018, 13th Edition, 771-786.
- KD Tripathi, Essentials of Medical Pharmacology, Anterior pituitary hormones, 7th edition, 2013, 237.
Disclaimer
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